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Protein Alignment Ir68b and Grin2b

DIOPT Version :9

Sequence 1:	NP_648548.1	Gene:	Ir68b / 39378	FlyBaseID:	FBgn0036250	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_036706.1	Gene:	Grin2b / 24410	RGDID:	2738	Length:	1482	Species:	Rattus norvegicus

Alignment Length:	696	Identity:	136/696 - (19%)
Similarity:	238/696 - (34%)	Gaps:	192/696 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 QVTYLYRCASCPASFDADYSALELDLYR----CVGSRLPVITRNMEAHELE---PFRRTDSLSIF 90
            :.||::..|:........|:.:...|..    .|.|..|....::...|.:   |.|..|.::|.
  Rat   236 EATYIFEVANSVGLTGYGYTWIVPSLVAGDTDTVPSEFPTGLISVSYDEWDYGLPARVRDGIAII 300

  Fly    91 QIPAAEKGDSLVRRILDMLNPHQRRKHMHKYLFV-WPNA---GRHQLLRLFRGSWAKKLLYGLAI 151
            ...|:           |||:.|.         |: .|.:   ..|: .|:::.:...:.|..:..
  Rat   301 TTAAS-----------DMLSEHS---------FIPEPKSSCYNTHE-KRIYQSNMLNRYLINVTF 344

  Fly   152 TGRENGTFDFDPFAWGGLQVIQRLDGEVPYAR--KVKDLRGYPLRFSMFTDPLMAMPRS------ 208
            .|| |.:|..|.:......||..|:.|..:.|  |.||   ..|:...:..|.|. |.:
  Rat   345 EGR-NLSFSEDGYQMHPKLVIILLNKERKWERVGKWKD---KSLQMKYYVWPRMC-PETEEQEDD 404

  Fly   209 -----PVETAGYQAVDGV--------------AARVVGE-----------------------MLN 231
                 .:|.|.:..|:.|              ..|::.|                       .::
  Rat   405 HLSIVTLEEAPFVIVESVDPLSGTCMRNTVPCQKRIISENKTDEEPGYIKKCCKGFCIDILKKIS 469

  Fly   232 ASVTYVFP---EDNESYGRCLPNGNYTGVVSDIVGGHTHFAPNSRFVLDCIWPAVEVLYPYTRRN 293
            .||.:.:.   ..|..:|:.: ||.:.|::.::|....:.|..|..:.:.....|:...|:....
  Rat   470 KSVKFTYDLYLVTNGKHGKKI-NGTWNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETG 533

  Fly   294 LHLVVPAS--AIQPEYLIFVRVFRRTVWYLLLVTLLVV----VLVFWVMQRL-------QRRIPR 345
            :.::|..|  .:.|.  .|:..|...||.::.|.||:|    |.||.....:       ..|.|
  Rat   534 ISVMVSRSNGTVSPS--AFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYNRCLADGREP- 595

  Fly   346 RGVIQF---QATWYEILEMFG-----KTHVGEPAGRLSSFSSMRTFLMGWILFSYVLSTIYFAKL 402
             |...|   :|.|.    ::|     ...|..|.|..|     :..:..|..|:.:....|.|.|
  Rat   596 -GGPSFTIGKAIWL----LWGLVFNNSVPVQNPKGTTS-----KIMVSVWAFFAVIFLASYTANL 650

  Fly   403 ESGFVRPSYEEQVDRVDDLVHLDVHIYAVTTMYDAVRSALTE----------HQY-GLLENRSRQ 456
            .:..::..|.:||..:.|......:.::....:..|.:..||          |.| |....|
  Rat   651 AAFMIQEEYVDQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNNYAEMHAYMGKFNQR--- 712

  Fly   457 LPLGIATSYYQPVVRRRDRRAAFIMRDFHARDFLAITYDSQAERPAYHIAREYLRSMICTYILPR 521
               |:..:.......:.|   |||             ||                :.:..|:..|
  Rat   713 ---GVDDALLSLKTGKLD---AFI-------------YD----------------AAVLNYMAGR 742

  Fly   522 GSPFLHRLESLYSG--FLEHGF------FEHW-RQMDL-ITRVGASPDAEEFLEDLGDQTDTDSG 576
            ....  :|.::.||  |...|:      ...| ||:|| |.::....:.|| ||.|.......:.
  Rat   743 DEGC--KLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEE-LEALWLTGICHNE 804

  Fly   577 SNELAIRNKKVVLTLDILQGAFYLWSVGIGISCLGFAVEHAHWFWR 622
            .||:....    |.:|.:.|.||:....:.:|.:.|..||. ::|:
  Rat   805 KNEVMSSQ----LDIDNMAGVFYMLGAAMALSLITFICEHL-FYWQ 845

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.