Protein Alignment Ir68b and gria2b

DIOPT Version :9

• Sequence 1: NP_648548.1
• Gene: Ir68b / 39378
• FlyBaseID: FBgn0036250
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: XP_005157361.1
• Gene: gria2b / 170451
• ZFINID: ZDB-GENE-020125-4
• Length: 897
• Species: Danio rerio
• Alignment Length: 732
• Identity: 124/732 - (16%)
• Similarity: 223/732 - (30%)
• Gaps: 292/732 - (39%)

  Fly    96 EKGDSLVRRIL-DMLNPHQRR---------------------KHMHKYLFVWPNAGRHQLLRLFR 138
            |:.|...|.:. |:.|..:||                     :|:..|.::..|.|       |.
Zfish   185 ERKDEAYRSLFQDLENKKERRVILDCEQDKVKDIMEQVITIGRHVKGYHYIIANLG-------FV 242

  Fly   139 GSWAKKLLYGLA-ITGRENGTFDFDPFA------WGGL-----------------------QVI- 172
            .....|:.||.| ::|.:...|| ||..      |..|                       ||:
Zfish   243 DGDLSKIQYGGANVSGFQIVDFD-DPLVSKFDQRWEALEEKEYPGADSKIRYTSALTYDAVQVMT 306

  Fly   173 --------QRLD-------GE------VPYA------RKVKDLR-----------GYPLRFSMFT 199
                    ||:|       |:      ||:|      |.:|.:|           .|..|.: :|
Zfish   307 EAFRYLHKQRIDISRRANNGDCLANPAVPWAQGVEIERALKQVRVDGLTGNIQFDQYGKRVN-YT 370

  Fly   200 DPLMAMPRSPVETAGY-QAVDGVAAR-----------------VVGEMLNASVTYVFPE------ 240
            ..:|.:..:.....|| ..||.:...                 :|..:|.|  .||..:
Zfish   371 VNVMELKSNGAVKIGYWNEVDKMVVTKSDLFPNDTMGLENKTVIVTTILEA--PYVMLKKNADLF 433

  Fly   241 -DNESY-GRCLP-------------------NGNY----------TGVVSDIVGGHTHFAPNSRF 274
             |||.| |.|:.                   :|.|          .|:|.::|.|....|.....
Zfish   434 MDNERYEGYCVDLAAEIAKHCGFKYQLKIVGDGKYGARDAETKIWNGMVGELVYGKADIAVAPLT 498

  Fly   275 VLDCIWPAVEVLYPYTRRNLHLVV--PASAIQPEYLIFVRVFRRTVWYLLLVTLLVVVLVFWVMQ 337
            :.......::...|:....:.:::  |..: :|....|:......:|..::...:.|.:|.:::.
Zfish   499 ITLVREEVIDFSKPFMSLGISIMIKKPQKS-KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVS 562

  Fly   338 RLQRRIPRRGVIQFQATWYEILEMFGKTHVGEPAGRLSSFSSMRTFLMG---------------- 386
            |.       ...::....||    .|:....|.......|:|: .|.:|
Zfish   563 RF-------SPYEWHTEEYE----DGQIQTNESTNEFGIFNSL-WFSLGAFMRQGCDISPRSLSG 615

  Fly   387 ------WILFSYVLSTIYFAKLESGFVRPSYEEQVDRVDDLVHLDVHIYAVTTMYDAVRSALTEH 445
                  |..|:.::.:.|.|.|.:..........::..:||                  :..||.
Zfish   616 RIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL------------------AKQTEI 662

  Fly   446 QYGLLENRSRQLPLGIATSYYQPVVRRRDRRAAFIMRDFHARDFLAI-----TYDSQAERPAYHI 505
            .||.|::.|                          .::|..|..:|:     ||...|| |:..:
Zfish   663 AYGTLDSGS--------------------------TKEFFRRSKIALFDKMWTYMKGAE-PSVFV 700

  Fly   506 ---AREYLRSMICTYILPRGSPFLHRLESLYSGFLEHGFFEHWRQMDLITRVGASPDAEEF---- 563
               |...:|      :......:.:.|||..:.::|.      |:.....:||.:.|::.:
Zfish   701 KTTAEGVMR------VRKSKGKYAYLLESTMNEYIEQ------RKPCDTMKVGGNLDSKGYGIAT 753

  Fly   564 ----------------LEDLG-----------DQTDTDSGSNELAIRNKKVVLTLDILQGAFYLW 601
                            |.:.|           |:.:..||..:  .:.|...|:|..:.|.||:.
Zfish   754 PKGSSLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGD--SKEKTSALSLSNVAGVFYIL 816

  Fly   602 SVGIGISCLGFAVEHAH 618
            ..|:|::.|...||..:
Zfish   817 VGGLGLAMLVALVEFCY 833

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68b	NP_648548.1	Lig_chan	333..607	CDD:278489	52/334 (16%)
gria2b	XP_005157361.1	PBP1_iGluR_AMPA_GluR2	27..395	CDD:107384	43/218 (20%)
		ANF_receptor	55..377	CDD:279440	39/200 (20%)
		PBP2_iGluR_AMPA	410..790	CDD:270433	68/451 (15%)
		Lig_chan	542..820	CDD:278489	54/348 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591893
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930