Protein Alignment Ir68b and gria2b

DIOPT Version :10

• Sequence 1: NP_648548.1
• Gene: Ir68b / 39378
• FlyBaseID: FBgn0036250
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: XP_068069253.1
• Gene: gria2b / 170451
• ZFINID: ZDB-GENE-020125-4
• Length: 944
• Species: Danio rerio
• Alignment Length: 760
• Identity: 129/760 - (16%)
• Similarity: 222/760 - (29%)
• Gaps: 301/760 - (39%)

  Fly    96 EKGDSLVRRIL-DMLNPHQRR---------------------KHMHKYLFVWPNAGRHQLLRLFR 138
            |:.|...|.:. |:.|..:||                     :|:..|.::..|.|       |.
Zfish   185 ERKDEAYRSLFQDLENKKERRVILDCEQDKVKDIMEQVITIGRHVKGYHYIIANLG-------FV 242

  Fly   139 GSWAKKLLYGLA-ITGRENGTFDFDPFA------WGGL-----------------------QVI- 172
            .....|:.||.| ::|.:...|| ||..      |..|                       ||:
Zfish   243 DGDLSKIQYGGANVSGFQIVDFD-DPLVSKFDQRWEALEEKEYPGADSKIRYTSALTYDAVQVMT 306

  Fly   173 --------QRLD-------GE------VPYA------RKVKDLR-----------GYPLRFSMFT 199
                    ||:|       |:      ||:|      |.:|.:|           .|..|.: :|
Zfish   307 EAFRYLHKQRIDISRRANNGDCLANPAVPWAQGVEIERALKQVRVDGLTGNIQFDQYGKRVN-YT 370

  Fly   200 DPLMAMPRSPVETAGY-QAVDGVAAR-----------------VVGEMLNASVTYVFPE------ 240
            ..:|.:..:.....|| ..||.:...                 :|..:|.|  .||..:
Zfish   371 VNVMELKSNGAVKIGYWNEVDKMVVTKSDLFPNDTMGLENKTVIVTTILEA--PYVMLKKNADLF 433

  Fly   241 -DNESY-GRCLP-------------------NGNY----------TGVVSDIVGGHTHFAPNSRF 274
             |||.| |.|:.                   :|.|          .|:|.::|.|....|.....
Zfish   434 MDNERYEGYCVDLAAEIAKHCGFKYQLKIVGDGKYGARDAETKIWNGMVGELVYGKADIAVAPLT 498

  Fly   275 VLDCIWPAVEVLYPYTRRNLHLVV--PASAIQPEYLIFVRVFRRTVWYLLLVTLLVVVLVFWVMQ 337
            :.......::...|:....:.:::  |..: :|....|:......:|..::...:.|.:|.:::.
Zfish   499 ITLVREEVIDFSKPFMSLGISIMIKKPQKS-KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVS 562

  Fly   338 RLQRRIPRRGVIQFQATWYEILEMFGKTHVGEPAGRLSSFSSMRTFLMG---------------- 386
            |.       ...::....||    .|:....|.......|:|: .|.:|
Zfish   563 RF-------SPYEWHTEEYE----DGQIQTNESTNEFGIFNSL-WFSLGAFMRQGCDISPRSLSG 615

  Fly   387 ------WILFSYVLSTIYFAKLESGFVRPSYEEQVDRVDDLVHLDVHIYAVTTMYDAVRSALTEH 445
                  |..|:.::.:.|.|.|.:..........::..:||                  :..||.
Zfish   616 RIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL------------------AKQTEI 662

  Fly   446 QYGLLENRSRQLPLGIATSYYQPVVRRRDRRAAF-----IMRDFHARDFLAITYD------SQAE 499
            .||.|::       |....::     ||.:.|.|     .|:......|:..|.:      ....
Zfish   663 AYGTLDS-------GSTKEFF-----RRSKIALFDKMWTYMKGAEPSVFVKTTAEGVMRVRKSKG 715

  Fly   500 RPAYHIAREYLRSMICTYI-----------------------LPRGSPFLHRLESLYSGFLEHGF 541
            :.||     .|.|.:..||                       .|:||...:.:........|.|.
Zfish   716 KYAY-----LLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGL 775

  Fly   542 FEH-----W------------------RQMD------LITRVGASPDAEEFLE----DLGDQTDT 573
            .:.     |                  .|.|      .:.::......::...    |.|:....
Zfish   776 LDKLKNKWWYDKGECGSGGGDSKVSPREQSDGTPVNLAVLKLSEQGTLDKLKNKWWYDKGECGAK 840

  Fly   574 DSGSNELAIRNKKVVLTLDILQGAFYLWSVGIGISCLGFAVEHAH 618
            ||||.|     |...|:|..:.|.||:...|:|::.|...||..:
Zfish   841 DSGSKE-----KTSALSLSNVAGVFYILVGGLGLAMLVALVEFCY 880

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68b	NP_648548.1	None
gria2b	XP_068069253.1	PBP1_iGluR_AMPA_GluR2	27..397	CDD:380612	43/220 (20%)
		PBP2_iGluR_AMPA	410..790	CDD:270433	66/429 (15%)