Protein Alignment Ir68b and grin3bb

DIOPT Version :9

• Sequence 1: NP_648548.1
• Gene: Ir68b / 39378
• FlyBaseID: FBgn0036250
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: XP_017213803.2
• Gene: grin3bb / 100333101
• ZFINID: ZDB-GENE-131122-77
• Length: 1114
• Species: Danio rerio
• Alignment Length: 771
• Identity: 146/771 - (18%)
• Similarity: 243/771 - (31%)
• Gaps: 242/771 - (31%)

  Fly    10 QWYLPGIYALAEIACRIAVEQNVQVTYLYRCASCPAS---FDAD--------YSALEL------- 56
            ||:|.....|:....|:|...:....:.....|.|||   |.||        .||.:|
Zfish   215 QWHLRAALNLSHSTARMANISDFLSEHFNLDHSPPASVLLFGADPECASSVLRSAHDLGLTLPTV 279

  Fly    57 ----------DLYRCVGSRLPVITRNMEAHELEPFRRTDSLSIFQIPAAEKGDSLVR-------- 103
                      |....:|..|.::......|:...|..:|:|.:  |..|....::||
Zfish   280 HWIMGHPLSPDALHSIGLPLGLLAYGEVDHKPLDFYISDALQL--INRAVTAATVVRPDLALIQN 342

  Fly   104 --RILDMLNPHQ------------------------------RRKHMHKYLFVW----PNAGRHQ 132
              ...|..|.|:                              .|.|....:.:|    ...|:..
Zfish   343 MVNCFDKPNKHELPSSGQYIARFLSNTSFVGLTGPVIVQRNLSRVHTSHKVHIWSLRRDAVGQPT 407

  Fly   133 LLRLFRGSWAKKLLYGLAITGRENGTFDFDPFAWGGLQVIQRLDGEVPYARKVKDLR-GYP---- 192
            .:.:  |||.     |..:...|.|       .|.|....||.:|::  .|:.:..| |:|
Zfish   408 WVTV--GSWE-----GGRLNVEEQG-------LWQGSSPRQRTEGQM--GREGRRWRAGFPVSGS 456

  Fly   193 -LRFSMFTDPLMAMPRSPVE----TAGYQAVDG------VAARVVGEMLNASVTYVFPEDNE-SY 245
             ||.....:......|...|    .||...:|.      ....:..|....:.:::.|:.:: .|
Zfish   457 RLRVVTLVEHPFVFTREVDEDGNCPAGQYCLDAGTNSSETLDHLYAERAQGNKSFLPPDYSKCCY 521

  Fly   246 GRCL---------------------------PNGNYTGVVSDIVGGHTHFAPNSRFVLDCIWPAV 283
            |.|:                           ..|.:||:|.|::.|....|..|..:.......:
Zfish   522 GYCIDLLEKLSEDMNFEFDLYIVGDGKYGAVKGGQWTGLVGDLLSGVADMAVTSFSINSARSKVI 586

  Fly   284 EVLYPYTRRNLHLVVPASAIQPEYLIFVRVFRRTVWYLLLVTLLVVVLVFWVMQRLQRRIPRRGV 348
            :...|:...:|.::|.:.........|:.....::|..:.|.|.:..|..
Zfish   587 DFTSPFFSTSLGILVRSKDTAAPIGAFMWPLHWSMWMGIFVALHITALFL--------------- 636

  Fly   349 IQFQATWYEILEMFGKTHVGEPAGRLSSFSSM----------RT------------FLMG-WILF 390
                 |.||....||.|..|....::.|:||.          ||            |||. |.:|
Zfish   637 -----TLYEWKSPFGMTPHGRNRVKVFSYSSALNLCYAILFGRTVSSKTPKCWTGRFLMNLWAIF 696

  Fly   391 SYVLSTIYFAKLESGFVRPSYEEQVDRVDDLVHLDVHIYAVTTMYDAVRSALTE----------H 445
            ..::.:.|.|.|.:..|.....|:|..:.|   ..:|..:....:..||.:..|          |
Zfish   697 CLLVLSSYTANLAAVMVGEKTFEEVSGIHD---AKLHHPSQGFRFGTVRESSAEDYMKKSFPEMH 758

  Fly   446 QYGLLENRSRQLPLGIATSYYQPVVRRRDRRAAFIMRDFHARDFLAITYDSQAE-----RP---- 501
            :| :.:......|.|:||....|     .:..|||| |....|: .::.|:..:     :|
Zfish   759 EY-MRKFNEPTTPDGVATLKTDP-----PQLDAFIM-DKALLDY-EVSIDADCKLLTVGKPFAIE 815

  Fly   502 AYHIAREYLRSMICTYILPRGSPFLHRLESLYSGFLEHGFFEHWRQMDLITRVGASPDAEEFLED 566
            .|.|.            ||:.||....:....|.:...|:      ||::      .|....:..
Zfish   816 GYGIG------------LPQNSPLTSNISEFVSRYKSDGY------MDML------HDKWYKVVP 856

  Fly   567 LGDQTDTDSGSNELAIRNKKVVLTLDILQGAFYLWSVGIGISCLGFAVEHAHWFWR 622
            .|.:....:.:.::.||:         ..|.|.|..||:..:.|..|.|||  |:|
Zfish   857 CGKRVFAVTETLQMGIRH---------FSGLFVLLCVGVTGALLTLAGEHA--FYR 901

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68b	NP_648548.1	Lig_chan	333..607	CDD:278489	62/315 (20%)
grin3bb	XP_017213803.2	PBP1_iGluR_NMDA_NR3	29..428	CDD:107372	40/228 (18%)
		PBP2_iGluR_NMDA_Nr3	457..852	CDD:270438	82/449 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591838
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930