DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment yps and Lin28a

DIOPT Version :9

Sequence 1:	NP_524033.2	Gene:	yps / 39377	FlyBaseID:	FBgn0022959	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_665832.1	Gene:	Lin28a / 83557	MGIID:	1890546	Length:	209	Species:	Mus musculus

Alignment Length:	150	Identity:	49/150 - (32%)
Similarity:	65/150 - (43%)	Gaps:	38/150 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 AQQQPEQQQNPPNPQEQDHEQEPLDELQGQQGQPAPPTKEVIATKVTGTVKWFNVKSGYGFINRN 81
            |::.||:.  ||:      .....||.|...|              .|..|||||:.|:||::..
Mouse    17 AEKAPEEA--PPD------AARAADEPQLLHG--------------AGICKWFNVRMGFGFLSMT 59

  Fly    82 -------DTREDVFVHQSAIARNNPKKAVRSVGDGEVVEFDVVIGEKGNEAANVTGPSGEPVRGS 139
                   |...|||||||.:    ..:..||:.:||.|||......||.|:..||||.|....||
Mouse    60 ARAGVALDPPVDVFVHQSKL----HMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGS 120

  Fly   140 QFAADKRRNFRPWMKKNRRK 159
            : ...|.:|    |:|.|.|
Mouse   121 E-RRPKGKN----MQKRRSK 135

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yps	NP_524033.2	CSD	62..131	CDD:278729	29/75 (39%)
Lin28a	NP_665832.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31		5/21 (24%)
		CSP_CDS	42..111	CDD:239905	28/72 (39%)
		Flexible linker	113..136		8/27 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	177..209
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1278
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000228
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810