DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6793 and Crtp

DIOPT Version :9

Sequence 1:	NP_648541.1	Gene:	CG6793 / 39369	FlyBaseID:	FBgn0036242	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_524736.1	Gene:	Crtp / 44276	FlyBaseID:	FBgn0029501	Length:	745	Species:	Drosophila melanogaster

Alignment Length:	577	Identity:	142/577 - (24%)
Similarity:	252/577 - (43%)	Gaps:	103/577 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PVVISNKRFQRIRAHATQAAKQEQLHQQQLREEADEKLRIGGEELLRKFAGRNLCITREEECARE 84
            |||||.|||..|:..:.|..|..|:...:......:.|:.|.|.|...|...|        ..:.
  Fly    24 PVVISAKRFAAIKGRSRQDEKHAQMEAVEEERRYRQYLKDGNELLCSLFTDPN--------APKV 80

  Fly    85 LKQLQAEQLEAKRLAEEESKAARLEHQKNRKKRIEAAQKLLEQLRPGPRELQCARLQSEVMRSVN 149
            .|..:|:..||..:.::..  .:|..::.||:||..|.:||:||:||||.|..|.:.||::....
  Fly    81 KKSARAQSKEAMAVVKDVD--TKLADERLRKQRILRANRLLDQLKPGPRALHQALIYSEMIHQRK 143

  Fly   150 VQREVQAEFARVNQQQKELDRKIFQEQVLR-GFEEAQQRHKEQCQQLSEHKKELLHLIAERERER 213
            ....:..|.|...:.|:..|.::....::. |....::....|..:..||.:.:...||:|.|
  Fly   144 YNEALNEEIAEAARAQERADEEMCPAALVPFGHATEEEEVARQTAKNMEHAELMRADIAQRAR-- 206

  Fly   214 QATKAKELEEALKERERNERMMKDQ----QAK---EKELQAAKQRKKKDEALASLVMSDQRQKRL 271
                       ::|.||.:|:.::|    |.|   :||.:|.|::|.:..|.......:..|::.
  Fly   207 -----------IREAEREQRVFEEQVDRAQYKCLQDKEEKALKEKKARKIAFNRKAYKEALQEKA 260

  Fly   272 QMLEEMEQVRCD----------------IHNKAKGDLEQLKRDRAKERVDQRIR---RNEKLAKE 317
            ::.|. |:: ||                :.::....::||::.|.:||..|.:|   ..:.|.|:
  Fly   261 EIAEH-ERI-CDAIDDRRNCVYIVASRNLDSRYGSHVKQLRQKRQEERELQALRVSQAQQVLQKK 323

  Fly   318 LAPRLHYSAREDEERH--KRQLEEMRKVHSAEQAKWRKSKEQAKNARLAVQREEEGLAKKSRQKA 380
            |..|    ..:.|:||  :.|:::.|:         :..:|.....|.|.|:.|.      :|.|
  Fly   324 LEER----QIDAEDRHAFETQVDDSRR---------QCEREMLAKERRAYQKLER------KQDA 369

  Fly   381 EEDRRLAEEQ------RLQNHQTNVQFKRQQREEHIQRIRKLRQDLDEQVKKRIEEETRPGTNY- 438
            |:.||..|.|      ||:|.:.|..|...|:.:..:...:||..|..|.::.:|:......|.
  Fly   370 EKLRRQQELQRFHVARRLKNAEANRFFDASQKRKRDKVKEELRNVLFGQREEFLEKRRAELMNLA 434

  Fly   439 --NREAQLEELREDAFFFDYARQLMDEAQAKGCPLKPFIRAVGQYKNDNRIGAEIRIPRHMITRL 501
              |.:..||   :|..||:.|.::|:|::..|.||.|...||.:|:..|::  ::|
  Fly   435 ACNEDPYLE---DDKKFFEQAVEIMEESRKVGRPLYPIATAVDRYERQNQL--DMR--------- 485

  Fly   502 PMGRRTQGDSQAE-------GKEKPSDKQEPNSEKLSKEEKLLRQKIDENLKKIEAL 551
            |.||..:..|..:       .|.:.:.::....||..:|:...|.:|..|..||:.|
  Fly   486 PEGRMVKRSSLRDYCWPGFFSKAELAYRKYEQREKCREEQVADRHQIYCNSVKIKKL 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6793	NP_648541.1	TPH	86..431	CDD:290579	91/379 (24%)
Crtp	NP_524736.1	PTZ00121	<243..>461	CDD:173412	55/241 (23%)
Crtp	NP_524736.1	PHA03307	575..>745	CDD:223039
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2CAYV
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR39944
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.000