DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rols and AT1G10340

DIOPT Version :9

Sequence 1:	NP_729778.1	Gene:	rols / 39368	FlyBaseID:	FBgn0041096	Length:	1900	Species:	Drosophila melanogaster
Sequence 2:	NP_563867.1	Gene:	AT1G10340 / 837573	AraportID:	AT1G10340	Length:	578	Species:	Arabidopsis thaliana

Alignment Length:	478	Identity:	107/478 - (22%)
Similarity:	169/478 - (35%)	Gaps:	125/478 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1381 ILCIAAHEGILPMVSLLLEFGAD-VGLTNSQGCTPLILAAMRGHCDVVRPLVAAGSSL-GQLDIT 1443
            :|.:||..|...:||.::|.... |...|:...|||.|||:.|..::|..::..|..: ...:|.
plant    40 VLHMAAKFGHRELVSKIIELRPSLVSSRNAYRNTPLHLAAILGDVNIVMQMLETGLEVCSARNIN 104

  Fly  1444 QRCALVHAARMGHLSVVKYLLACDWSPRPHSQDVTRSVALQQALIGAAAQAHC---KILEDLLDL 1505
            ....|..|.|...:...: |:|          :.|:|:.|.:.::..::.:..   .|||...||
plant   105 NHTPLHLACRSNSIEAAR-LIA----------EKTQSIGLGELILAISSGSTSIVGTILERFPDL 158

  Fly  1506 NETEFDLDVNGMEPSSGELALTAAARHGCIDVVGIL--LSRGAQIDARNRQGYSALWLAVKEGHW 1568
            ...|..:    :|..|....|..|...|..::..||  |.:|.: :|.|..|.|.|.|||..|..
plant   159 AREEAWV----VEDGSQSTLLHHACDKGDFELTTILLGLDQGLE-EALNPNGLSPLHLAVLRGSV 218

  Fly  1569 SVVEHLLQRGALLDEPLGQTRKTPLMIAAEEGHLELVDLLLARGAQREAQDHEGFTALSWACLRG 1633
            .::|..|.             |.||..::.....|.|..|.||....:|
plant   219 VILEEFLD-------------KVPLSFSSITPSKETVFHLAARNKNMDA---------------- 254

  Fly  1634 HLAAAKTLIEHGCNR----HHEDHNGRTALDLAAYQGAASLVIYILEQGGNLEHIDVHGMRPLDR 1694
            .:..|::|   |.|.    ...|.:|.|.|.:||                     .|....||.|
plant   255 FVFMAESL---GINSQILLQQTDESGNTVLHIAA---------------------SVSFDAPLIR 295

  Fly  1695 AIACRNIQAVQVFLRKGAKLGPTTWSMAMGKPEILVILLNKLLEDGNVLYRKNRF-----QEAAH 1754
            .|..:||    |.:....|:|...:.           ||.:..:|..:|.|..||     ||.
plant   296 YIVGKNI----VDITSKNKMGFEAFQ-----------LLPREAQDFELLSRWLRFGTETSQEL-- 343

  Fly  1755 RYQYALRKISGLEQLLERNAIFAQLRTNLLLNLSRCKRKLNELDASIDLATQAIAQKPHSYEGYY 1819
                      ..|..:|::....::....||.:             |.:.|..||::..|.|...
plant   344 ----------DSENNVEQHEGSQEVEVIRLLRI-------------IGINTSEIAERKRSKEQEV 385

  Fly  1820 ARAKARMELGALNEALVDANEAM 1842
            .|.:..:|.....|||.:|...:
plant   386 ERGRQNLEYQMHIEALQNARNTI 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rols	NP_729778.1	zf-RING_5	327..364	CDD:291308
		Ank_5	1363..1418	CDD:290568	12/37 (32%)
		ANK	1378..1503	CDD:238125	30/126 (24%)
		ANK repeat	1382..1408	CDD:293786	8/26 (31%)
		ANK repeat	1410..1441	CDD:293786	9/31 (29%)
		Ank_2	1415..1552	CDD:289560	32/142 (23%)
		ANK	1486..1609	CDD:238125	31/127 (24%)
		ANK repeat	1486..1518	CDD:293786	6/34 (18%)
		ANK repeat	1521..1552	CDD:293786	9/32 (28%)
		Ank_2	1526..1619	CDD:289560	27/94 (29%)
		ANK	1549..1675	CDD:238125	30/129 (23%)
		ANK repeat	1554..1586	CDD:293786	9/31 (29%)
		ANK repeat	1591..1619	CDD:293786	8/27 (30%)
		Ank_2	1593..1685	CDD:289560	17/95 (18%)
		ANK repeat	1621..1652	CDD:293786	4/34 (12%)
		ANK repeat	1654..1685	CDD:293786	5/30 (17%)
		Ank_2	1659..1735	CDD:289560	15/75 (20%)
		ANK repeat	1687..1712	CDD:293786	7/24 (29%)
		TPR_11	1736..1812	CDD:290150	15/80 (19%)
		TPR repeat	1736..1768	CDD:276809	7/36 (19%)
		TPR repeat	1773..1810	CDD:276809	5/36 (14%)
		TPR_11	1783..1843	CDD:290150	14/60 (23%)
		TPR repeat	1815..1843	CDD:276809	7/28 (25%)
AT1G10340	NP_563867.1	ANK	38..152	CDD:238125	27/122 (22%)
		ANK repeat	38..68	CDD:293786	8/27 (30%)
		Ank_2	41..131	CDD:289560	25/100 (25%)
		ANK repeat	70..102	CDD:293786	9/31 (29%)
		Ank_2	136..227	CDD:289560	26/108 (24%)
		ANK repeat	170..202	CDD:293786	9/32 (28%)
		ANK	173..285	CDD:238125	35/144 (24%)
		Ank_2	209..309	CDD:289560	34/156 (22%)
		ANK repeat	238..274	CDD:293786	10/54 (19%)
		PGG	399..509	CDD:290670	4/10 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1009
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000