DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rols and AT5G60070

DIOPT Version :9

Sequence 1:	NP_729778.1	Gene:	rols / 39368	FlyBaseID:	FBgn0041096	Length:	1900	Species:	Drosophila melanogaster
Sequence 2:	NP_200815.1	Gene:	AT5G60070 / 836129	AraportID:	AT5G60070	Length:	548	Species:	Arabidopsis thaliana

Alignment Length:	476	Identity:	121/476 - (25%)
Similarity:	187/476 - (39%)	Gaps:	111/476 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  1413 TPLILAAMRGHCDVVRPLVA----AGSSLGQLDITQRCALVHAARMGHLSVVKYLLACDWSPRPH 1473
            ||..:||        :|.|.    |....|:.:.:|   |:.|.|.|..|.||.:|    |....
plant     8 TPAPMAA--------KPTVVKKTMAKQFTGKREDSQ---LLSAVRRGDFSAVKEIL----SNHME 57

  Fly  1474 SQDVTRSVALQQ------ALIGAAAQAHCKILEDLL---DLNETEFDLDVNGMEPSSGELALTAA 1529
            |:|..|.:..:|      ||..||......::.:|:   ||.:.|.... ||.:|      ...|
plant    58 SEDELRDLLRKQNQCGETALYVAAEYGDADVVAELIKYYDLEDAETKAR-NGFDP------FHIA 115

  Fly  1530 ARHGCIDVVGILLSRGAQ----IDARNRQGYSALWLAVKEGHWSVVEHLLQ-RGALLDEPLGQTR 1589
            |:.|.:||:.:|:....:    :|..|.   :||..|..:||..|||:||: .|:.|........
plant   116 AKQGELDVLRVLMEEHPELSMTVDLSNT---TALHTAAAQGHVEVVEYLLEAAGSSLAAIAKSNG 177

  Fly  1590 KTPLMIAAEEGHLELVDLLLARGAQREAQ-DHEGFTALSWACLRGHLAAAKTLIE--------HG 1645
            ||.|..||..||.|:|..::|.......: |.:|.|.|       |:|.....|:        |.
plant   178 KTALHSAARNGHAEVVKAIVAVEPDTATRTDKKGQTPL-------HMAVKGQSIDVVVELMKGHR 235

  Fly  1646 CNRHHEDHNGRTALDLAAYQGAASLVIYIL---EQGGNLEHIDVHGMRPLDRAIACRNIQAVQVF 1707
            .:.:..|..|.|||.:|..:|...:|..:|   |...:.:.|:..|..|||.|....:.|...|.
plant   236 SSLNMADSKGNTALHVATRKGRIKIVELLLDNNETSPSTKAINRAGETPLDTAEKTGHPQIAAVL 300

  Fly  1708 LRKG---AK-LGPTTWSMAMGKPEILVILLNKLLED--GNVLYRKNRFQEAAHRYQYALRKIS-- 1764
            ..:|   || :..||...|..:       |.:.:.|  ..|.::....:|...|.|...::|:
plant   301 KTRGVPSAKAINNTTRPNAARE-------LKQTVSDIKHEVHHQLEHARETRKRVQGIAKRINKM 358

  Fly  1765 ---GLEQLLERNAIFAQLRTNLLLNLSRCKRKLNELDASIDLATQAIAQKPHSYEGYYARAKARM 1826
               ||:..:....:.|.|                       :||.|.| ...:..|.||.
plant   359 HVEGLDNAINSTTVVAVL-----------------------IATVAFA-AIFTVPGQYAD----- 394

  Fly  1827 ELGAL--NEALVDANEAMQQA 1845
            ||.:|  .::|.:||.|.:.|
plant   395 ELSSLLPGQSLGEANIADRPA 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rols	NP_729778.1	zf-RING_5	327..364	CDD:291308
		Ank_5	1363..1418	CDD:290568	2/4 (50%)
		ANK	1378..1503	CDD:238125	26/99 (26%)
		ANK repeat	1382..1408	CDD:293786
		ANK repeat	1410..1441	CDD:293786	8/31 (26%)
		Ank_2	1415..1552	CDD:289560	38/153 (25%)
		ANK	1486..1609	CDD:238125	40/130 (31%)
		ANK repeat	1486..1518	CDD:293786	10/34 (29%)
		ANK repeat	1521..1552	CDD:293786	7/34 (21%)
		Ank_2	1526..1619	CDD:289560	30/98 (31%)
		ANK	1549..1675	CDD:238125	40/135 (30%)
		ANK repeat	1554..1586	CDD:293786	12/32 (38%)
		ANK repeat	1591..1619	CDD:293786	9/28 (32%)
		Ank_2	1593..1685	CDD:289560	26/103 (25%)
		ANK repeat	1621..1652	CDD:293786	7/38 (18%)
		ANK repeat	1654..1685	CDD:293786	9/33 (27%)
		Ank_2	1659..1735	CDD:289560	21/82 (26%)
		ANK repeat	1687..1712	CDD:293786	8/27 (30%)
		TPR_11	1736..1812	CDD:290150	14/82 (17%)
		TPR repeat	1736..1768	CDD:276809	8/38 (21%)
		TPR repeat	1773..1810	CDD:276809	5/36 (14%)
		TPR_11	1783..1843	CDD:290150	14/61 (23%)
		TPR repeat	1815..1843	CDD:276809	10/29 (34%)
AT5G60070	NP_200815.1	Ank_2	36..137	CDD:403870	30/111 (27%)
		ANK repeat	36..70	CDD:293786	12/37 (32%)
		ANK repeat	73..105	CDD:293786	8/31 (26%)
		ANK repeat	107..139	CDD:293786	9/37 (24%)
		ANKYR	111..313	CDD:223738	60/217 (28%)
		Ank_2	112..202	CDD:403870	30/92 (33%)
		ANK repeat	141..174	CDD:293786	13/35 (37%)
		ANK repeat	176..208	CDD:293786	10/31 (32%)
		ANK repeat	210..242	CDD:293786	7/38 (18%)
		PGG	361..477	CDD:404788	19/84 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1009
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000