DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rols and AT5G54710

DIOPT Version :9

Sequence 1:	NP_729778.1	Gene:	rols / 39368	FlyBaseID:	FBgn0041096	Length:	1900	Species:	Drosophila melanogaster
Sequence 2:	NP_001332664.1	Gene:	AT5G54710 / 835560	AraportID:	AT5G54710	Length:	643	Species:	Arabidopsis thaliana

Alignment Length:	390	Identity:	91/390 - (23%)
Similarity:	151/390 - (38%)	Gaps:	90/390 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  1373 TDYMGGAPILCIAAHEGILPMVSLLLEFG-ADVGLTNSQGCTPLILAAMRGHCDVVRPLVAAGSS 1436
            |:..|..| |.:||..|...::..:|..| ||....|.||.|..|||.:..|.|....||....|
plant    14 TNVDGNTP-LHLAAEIGNESILWKMLRCGRADCMKINKQGQTAFILACLNNHLDAALTLVENMRS 77

  Fly  1437 LGQLDITQRCALVHAARMGHLSVV--KYL-----LACDWSPRPHSQDVTRSVALQQALIGAAAQA 1494
            :..:::       .||..|...|:  |.|     |..|       .|..:|..|.:|:.....:.
plant    78 MTMVEL-------DAAFTGQQPVIIDKMLEKFPSLVLD-------VDEEQSTLLHKAVTQRNEEY 128

  Fly  1495 HCKILE---DLLDLNETEFDLDVNGMEPSSGELALTAAARHGCIDVVGILLSRG-AQIDARNRQG 1555
            ..|:::   .|:.:.      :|:|..|      |..||..|.|:::..:|..| |:....|:||
plant   129 ATKVIDLCPSLVSVT------NVDGNTP------LHLAAEIGNINILWKMLETGEAECMKINKQG 181

  Fly  1556 YSALWLAVKEGHWSVVEHLLQRGALLDEPLGQTRKTPLMIAAEEGHLELVDLLLARGAQREAQ-D 1619
            .:|..||       .:.:.:....:|.|.........|..|..|....::|.:|.:....... |
plant   182 QTAFILA-------CLNNNVNSARILVEGTSSMTMVELNAAFSEQQQVIIDSILEKFPNLILDAD 239

  Fly  1620 HEGFTALSWACLRGHLAAAKTLIEHGCNRHHEDHNGRTALDLAAYQGAASLVIYILEQGGNLEHI 1684
            .|..|.|..||..|:|..|:||::...|:           ::|                   |.:
plant   240 EEQSTLLHKACKSGNLEMARTLLDVDVNQ-----------EIA-------------------EKV 274

  Fly  1685 DVHGMRPLDRAIACRNIQAVQVFLRKGAKLGPTTWSM-AMGKPEILVILLNKLLEDGNVLYRKNR 1748
            |..|:.||.||:...:::.::.||.|    .|::::: ..|..|.:..|..|        |:|.:
plant   275 DKDGLTPLHRAVINGSVEILKEFLCK----APSSFNITTQGTIETVFHLAAK--------YQKTK 327

Fly 1749 1748
plant 328 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rols	NP_729778.1	zf-RING_5	327..364	CDD:291308
		Ank_5	1363..1418	CDD:290568	16/45 (36%)
		ANK	1378..1503	CDD:238125	34/135 (25%)
		ANK repeat	1382..1408	CDD:293786	8/26 (31%)
		ANK repeat	1410..1441	CDD:293786	11/30 (37%)
		Ank_2	1415..1552	CDD:289560	33/147 (22%)
		ANK	1486..1609	CDD:238125	26/126 (21%)
		ANK repeat	1486..1518	CDD:293786	5/34 (15%)
		ANK repeat	1521..1552	CDD:293786	8/31 (26%)
		Ank_2	1526..1619	CDD:289560	21/94 (22%)
		ANK	1549..1675	CDD:238125	26/126 (21%)
		ANK repeat	1554..1586	CDD:293786	7/31 (23%)
		ANK repeat	1591..1619	CDD:293786	5/28 (18%)
		Ank_2	1593..1685	CDD:289560	19/92 (21%)
		ANK repeat	1621..1652	CDD:293786	11/30 (37%)
		ANK repeat	1654..1685	CDD:293786	2/30 (7%)
		Ank_2	1659..1735	CDD:289560	15/76 (20%)
		ANK repeat	1687..1712	CDD:293786	8/24 (33%)
		TPR_11	1736..1812	CDD:290150	2/13 (15%)
		TPR repeat	1736..1768	CDD:276809	2/13 (15%)
		TPR repeat	1773..1810	CDD:276809
		TPR_11	1783..1843	CDD:290150
		TPR repeat	1815..1843	CDD:276809
AT5G54710	NP_001332664.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1009
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000