DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rols and AT2G31820

DIOPT Version :9

Sequence 1:	NP_729778.1	Gene:	rols / 39368	FlyBaseID:	FBgn0041096	Length:	1900	Species:	Drosophila melanogaster
Sequence 2:	NP_180741.1	Gene:	AT2G31820 / 817739	AraportID:	AT2G31820	Length:	662	Species:	Arabidopsis thaliana

Alignment Length:	501	Identity:	120/501 - (23%)
Similarity:	185/501 - (36%)	Gaps:	151/501 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly  1368 SPNHRTDYMGGAPILCIAAHEGILPMVSLLLEFGAD-----VGLTNSQGCTPLILAAMRGHCDVV 1427
            ||..|     |...|.|||..|.|..|..|:....|     :...|.:|.|||..||..||..||
plant   146 SPGKR-----GDSSLHIAARTGNLSKVKELIRGCGDELKELLSKQNLEGETPLYTAAENGHSIVV 205

  Fly  1428 RPL----------VAAGSSLGQLDITQRCALVHAARMGHLSVVKYLLACDWSPRPHSQDVTRSVA 1482
            ..:          :||.:......:        ||:.|||.|:|.||  :..|   :..:|..::
plant   206 EEMLKHMDLETASIAARNGFDPFHV--------AAKQGHLEVLKILL--ETFP---NLAMTTDLS 257

  Fly  1483 LQQALIGAAAQAHCKILEDLLDLNETEFDLDVNGMEPSSGELALTAAARHGCIDVVGILLSRGAQ 1547
            ...||..||.|.|..::..||     |.|.::..:..::|:.||.:|||.|.::||..|:.:...
plant   258 CTTALHTAATQGHIDVVNLLL-----ETDSNLAKIAKNNGKTALHSAARMGHVEVVKSLIGKDPS 317

  Fly  1548 IDAR-NRQGYSALWLAVKEGHWSVVEHLLQRGALLDEPLGQTRKTPLMIAAEEGHLELVDLLLAR 1611
            |..| :::|.:||.:|||..:..:|..|::....:.........|||.||..:|.:::|
plant   318 IGFRTDKKGQTALHMAVKGQNDGIVVELVKPDVAVLSVEDNKGNTPLHIATNKGRIKIV------ 376

  Fly  1612 GAQREAQDHEGFTALSWACLRGHLAAAKTLIEHGCNRHHEDHNGRTALDLAAYQGAASLVIYILE 1676
                             .||                                          :..
plant   377 -----------------RCL------------------------------------------VSF 382

  Fly  1677 QGGNLEHIDVHGMRPLDRAIACRNIQAVQVFLRKGAKLGPTTWSMAMGKPEILVILLNKLLED-- 1739
            :|.||..|:..|..|||.:....|.:.|.|....||     ..:..:|||:.....|.:.:.|
plant   383 EGINLNPINKAGDTPLDVSEKIGNAELVSVLKEAGA-----ATAKDLGKPQNPAKQLKQTVSDIK 442

  Fly  1740 ---GNVLYRKN----RFQEAAHRYQYALRK--ISGLEQLLERNAIFAQLRTNLLLNLSRCKRKLN 1795
               .:.|.:..    |.|:.|.|    |:|  ||||...:....:.|.|
plant   443 HEVQSQLQQSRQTGVRVQKIAKR----LKKLHISGLNNAINSATVVAVL---------------- 487

  Fly  1796 ELDASIDLATQAIAQKPHSYEGYYARAKARMELGALNEALVDANEA 1841
                   :||.|.| ...:..|.|...:::.||  |.:|.: ||:|
plant   488 -------IATVAFA-AIFTIPGQYEEDRSKGEL--LGQAHI-ANKA 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rols	NP_729778.1	zf-RING_5	327..364	CDD:291308
		Ank_5	1363..1418	CDD:290568	18/54 (33%)
		ANK	1378..1503	CDD:238125	40/139 (29%)
		ANK repeat	1382..1408	CDD:293786	9/30 (30%)
		ANK repeat	1410..1441	CDD:293786	12/40 (30%)
		Ank_2	1415..1552	CDD:289560	42/147 (29%)
		ANK	1486..1609	CDD:238125	37/123 (30%)
		ANK repeat	1486..1518	CDD:293786	10/31 (32%)
		ANK repeat	1521..1552	CDD:293786	12/31 (39%)
		Ank_2	1526..1619	CDD:289560	25/93 (27%)
		ANK	1549..1675	CDD:238125	18/126 (14%)
		ANK repeat	1554..1586	CDD:293786	8/31 (26%)
		ANK repeat	1591..1619	CDD:293786	7/27 (26%)
		Ank_2	1593..1685	CDD:289560	10/91 (11%)
		ANK repeat	1621..1652	CDD:293786	2/30 (7%)
		ANK repeat	1654..1685	CDD:293786	3/30 (10%)
		Ank_2	1659..1735	CDD:289560	17/75 (23%)
		ANK repeat	1687..1712	CDD:293786	7/24 (29%)
		TPR_11	1736..1812	CDD:290150	18/86 (21%)
		TPR repeat	1736..1768	CDD:276809	12/42 (29%)
		TPR repeat	1773..1810	CDD:276809	5/36 (14%)
		TPR_11	1783..1843	CDD:290150	13/59 (22%)
		TPR repeat	1815..1843	CDD:276809	9/27 (33%)
AT2G31820	NP_180741.1	ANK repeat	150..186	CDD:293786	11/40 (28%)
		Ank_2	155..245	CDD:403870	31/99 (31%)
		ANK repeat	188..222	CDD:293786	11/33 (33%)
		ANK repeat	223..254	CDD:293786	10/43 (23%)
		Ank_2	228..321	CDD:403870	32/110 (29%)
		ANK repeat	256..289	CDD:293786	10/37 (27%)
		ANK repeat	291..323	CDD:293786	12/31 (39%)
		Ank_2	296..388	CDD:403870	29/156 (19%)
		ANK repeat	325..357	CDD:293786	8/31 (26%)
		ANK repeat	359..391	CDD:293786	12/96 (13%)
		PHA02736	<360..418	CDD:165103	20/122 (16%)
		PGG	473..585	CDD:404788	17/77 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1009
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000