DRSC/TRiP Functional Genomics Resources

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Protein Alignment rols and Ankrd65

DIOPT Version :9

Sequence 1:NP_729778.1 Gene:rols / 39368 FlyBaseID:FBgn0041096 Length:1900 Species:Drosophila melanogaster
Sequence 2:NP_001102897.1 Gene:Ankrd65 / 680734 RGDID:1588232 Length:365 Species:Rattus norvegicus


Alignment Length:335 Identity:101/335 - (30%)
Similarity:139/335 - (41%) Gaps:79/335 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly  1353 SPNLKVSRLVLLAGASPNHRTDYMGGAPILCIAAHEGILPMVSLLLEFGADVGLTNSQGCTPLIL 1417
            :|:|.:.  :|..|||...| |:.|..| |.:|...|..|:|.|||:.||..|..:..|.|||..
  Rat    45 APSLVMQ--LLRQGASVEER-DHTGRTP-LHLAVMRGHAPLVRLLLQRGALAGAVDHTGRTPLHE 105

  Fly  1418 AAMRGHCDVVRPLVAAGSS------------------LGQL-----------------DITQRCA 1447
            ||..||.:|...|:..|:|                  ||:.                 ||....|
  Rat   106 AAWHGHSNVAELLLRRGASAAAPCSQTGLTPLHGAAALGRTLLVTCFTAAPDSVPDVKDIRGWTA 170

  Fly  1448 LVHAARMGHLSVVKYLLACDWSPRPHSQDVTRSVALQQALIGAAAQAHCKILEDLLDLNETEFDL 1512
            ...||..|.|.|::.|.|            ..||.|..||:.:|.......|..||.|......|
  Rat   171 THWAAACGQLPVLELLTA------------GGSVDLDGALLVSAVAGSASALRLLLTLGAKVDAL 223

  Fly  1513 DV-----------------------NGMEPS----SGELALTAAARHGCIDVVGILLSRGAQIDA 1550
            |.                       :|.:|:    :...||..||..||:..:.:|:::|..:||
  Rat   224 DSTGATALGLAAGLGHHQEIEVLLGHGADPNIRDRNNRSALHRAASGGCLRAIQLLVAKGTDVDA 288

  Fly  1551 RNRQGYSALWLAVKEGHWSVVEHLLQRGALLDEPLGQTRKTPLMIAAEEGHLELVDLLLARGAQR 1615
            |:..|.:.|..|.:.||..||.|||.|||.:| ..|...||||.:|.|.||..:::|||:|||..
  Rat   289 RDSLGLTPLHYAARGGHREVVSHLLDRGAHVD-AAGWLHKTPLHLAVECGHTTILELLLSRGANP 352

  Fly  1616 EAQDHEGFTA 1625
            ..:...|..|
  Rat   353 SLRTQWGEVA 362

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rolsNP_729778.1 zf-RING_5 327..364 CDD:291308
Ank_5 1363..1418 CDD:290568 23/54 (43%)
ANK 1378..1503 CDD:238125 43/159 (27%)
ANK repeat 1382..1408 CDD:293786 11/25 (44%)
ANK repeat 1410..1441 CDD:293786 14/65 (22%)
Ank_2 1415..1552 CDD:289560 45/198 (23%)
ANK 1486..1609 CDD:238125 46/149 (31%)
ANK repeat 1486..1518 CDD:293786 10/54 (19%)
ANK repeat 1521..1552 CDD:293786 10/30 (33%)
Ank_2 1526..1619 CDD:289560 39/92 (42%)
ANK 1549..1675 CDD:238125 34/77 (44%)
ANK repeat 1554..1586 CDD:293786 14/31 (45%)
ANK repeat 1591..1619 CDD:293786 13/27 (48%)
Ank_2 1593..1685 CDD:289560 13/33 (39%)
ANK repeat 1621..1652 CDD:293786 2/5 (40%)
ANK repeat 1654..1685 CDD:293786
Ank_2 1659..1735 CDD:289560
ANK repeat 1687..1712 CDD:293786
TPR_11 1736..1812 CDD:290150
TPR repeat 1736..1768 CDD:276809
TPR repeat 1773..1810 CDD:276809
TPR_11 1783..1843 CDD:290150
TPR repeat 1815..1843 CDD:276809
Ankrd65NP_001102897.1 ANK 33..149 CDD:238125 35/107 (33%)
ANK repeat 33..63 CDD:293786 7/20 (35%)
Ank_2 37..123 CDD:289560 31/81 (38%)
ANK repeat 65..96 CDD:293786 13/31 (42%)
ANK repeat 98..123 CDD:293786 10/24 (42%)
ANK repeat 197..224 CDD:293786 7/26 (27%)
Ank_2 198..290 CDD:289560 20/91 (22%)
ANK 221..346 CDD:238125 39/125 (31%)
ANK repeat 227..257 CDD:293786 2/29 (7%)
ANK repeat 259..290 CDD:293786 10/30 (33%)
Ank_2 264..355 CDD:289560 39/91 (43%)
ANK repeat 292..323 CDD:293786 14/31 (45%)
ANK repeat 325..355 CDD:293786 14/29 (48%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166343657
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - LDO PTHR24166
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.030

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