DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rols and ankrd63

DIOPT Version :9

Sequence 1:	NP_729778.1	Gene:	rols / 39368	FlyBaseID:	FBgn0041096	Length:	1900	Species:	Drosophila melanogaster
Sequence 2:	XP_012810387.1	Gene:	ankrd63 / 101730682	XenbaseID:	XB-GENE-6036151	Length:	328	Species:	Xenopus tropicalis

Alignment Length:	145	Identity:	49/145 - (33%)
Similarity:	69/145 - (47%)	Gaps:	9/145 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly  1580 LLDEPLGQTRKTPLMIAA--EEGHL--ELVDLLLARGAQREAQDHEGFTALSWACLRGHLAAAKT 1640
            :::.|.|:..:||||.|.  .|..|  ..:.|||.:||...|||..|.||||.||..|||.|.|.
Frog    40 IVNSPAGEQGRTPLMFAVCLREAELRTRFLRLLLDKGADVNAQDEAGRTALSLACELGHLDAVKL 104

  Fly  1641 LIEHGCNRHHEDHNGRTALDLAAYQGAASLVIYILEQ----GGNLEHIDVHGMRPLDRAIACRNI 1701
            |::|..:....|..|..||..||..|.:..:.::|..    |..|:..:..|:..|:.|....|.
Frog   105 LVQHNADPELPDRAGNRALMYAASCGRSPELHFLLRSYKRFGLRLDVRNRAGVSALEAARLSGNR 169

  Fly  1702 QAVQVFL-RKGAKLG 1715
            :...... |:.||.|
Frog   170 ECEMALSGREAAKPG 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rols	NP_729778.1	zf-RING_5	327..364	CDD:291308
		Ank_5	1363..1418	CDD:290568
		ANK	1378..1503	CDD:238125
		ANK repeat	1382..1408	CDD:293786
		ANK repeat	1410..1441	CDD:293786
		Ank_2	1415..1552	CDD:289560
		ANK	1486..1609	CDD:238125	10/32 (31%)
		ANK repeat	1486..1518	CDD:293786
		ANK repeat	1521..1552	CDD:293786
		Ank_2	1526..1619	CDD:289560	15/42 (36%)
		ANK	1549..1675	CDD:238125	38/98 (39%)
		ANK repeat	1554..1586	CDD:293786	1/5 (20%)
		ANK repeat	1591..1619	CDD:293786	13/31 (42%)
		Ank_2	1593..1685	CDD:289560	37/99 (37%)
		ANK repeat	1621..1652	CDD:293786	14/30 (47%)
		ANK repeat	1654..1685	CDD:293786	9/34 (26%)
		Ank_2	1659..1735	CDD:289560	15/62 (24%)
		ANK repeat	1687..1712	CDD:293786	5/25 (20%)
		TPR_11	1736..1812	CDD:290150
		TPR repeat	1736..1768	CDD:276809
		TPR repeat	1773..1810	CDD:276809
		TPR_11	1783..1843	CDD:290150
		TPR repeat	1815..1843	CDD:276809
ankrd63	XP_012810387.1	ANKYR	<39..171	CDD:223738	45/130 (35%)
		ANK repeat	49..83	CDD:293786	13/33 (39%)
		ANK repeat	85..116	CDD:293786	14/30 (47%)
		ANK repeat	118..153	CDD:293786	9/34 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1073736at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010