Protein Alignment CG6928 and Slc26a5

DIOPT Version :10

• Sequence 1: NP_648539.1
• Gene: CG6928 / 39367
• FlyBaseID: FBgn0036240
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_110467.1
• Gene: Slc26a5 / 83819
• RGDID: 69334
• Length: 744
• Species: Rattus norvegicus
• Alignment Length: 640
• Identity: 167/640 - (26%)
• Similarity: 279/640 - (43%)
• Gaps: 139/640 - (21%)

  Fly     8 YRLLPGLKWLHGYTGQDAV-ADLIAGVTVGLTVLPQGLAYATLAGLEPQYGLYSAFVGGIIYAML 71
            |..||..|||..|..::.| .||::|::.|:..||||||:|.||.:.|.:||||:|...|:|...
  Rat    62 YMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPVFGLYSSFYPVIMYCFF 126

  Fly    72 GSCRQVTIGPTALLALMTSRHT------------GFGLGSGP--------AYAILLCLISGVVEL 116
            |:.|.::|||.|:::||.....            |....:|.        ..|:.:.|:||:::.
  Rat   127 GTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQF 191

  Fly   117 GMAVLKLGALVDLISLPVTVGFTSATAVIIGTSQLKGLLGLRGGSGSDFINTMRSVFGNLHKVRT 181
            .:.|.:.|.:...::.|:..|||:|.||.:.||.||.|.|::....|...:.:.|....|..|:
  Rat   192 CLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVK- 255

  Fly   182 GDFTLGLTSIIVLLLLRKLKDVKLDGRIRNLRTQQLVSGSI------WVIGTGRNALVVLVTSVL 240
               .|.:.|:.|.|::..|   .|.|:..|.|.::.:...|      .|:|||.:|...|
  Rat   256 ---NLNVCSLGVGLMVFGL---LLGGKEFNERFKEKLPAPIPLEFFAVVMGTGISAGFNL----- 309

  Fly   241 AYSTCEQMESCPFILTGKVKSGL-----PNVSLPKFETTILDRNGTEIRQNFEQMLSELGPSMLI 300
                   .||....:.|.:..||     |:.||  |....:|                    .:.
  Rat   310 -------HESYSVDVVGTLPLGLLPPANPDTSL--FHLVYVD--------------------AIA 345

  Fly   301 LPIIAVLGNVAISKAFG---GAGLSPTRELVALSMSNICGAFCSSMPVTGSFSRSAVNHASGVRT 362
            :.|:.....::::|...   |..:...:||:||.:.|..|:...:..::.|.|||.|...:|.:|
  Rat   346 IAIVGFSVTISMAKTLANKHGYQVDGNQELIALGICNSIGSLFQTFSISCSLSRSLVQEGTGGKT 410

  Fly   363 PLGGCYTS---VLVLLALGLLAPYFQYIPKAALSAVIISAV--IFMIEFEVIKPLWRCSRRELLP 422
            .|.||..|   :||:||.|.|   |:.:|:|.|||::|..:  :|| :|..:...||.|:.||..
  Rat   411 QLAGCLASLMILLVILATGFL---FESLPQAVLSAIVIVNLKGMFM-QFSDLPFFWRTSKIELTI 471

  Fly   423 GAITFVMSLAVGVEIGLLLGVSTDVAFLVYRAARPVLSV-SKLQTTN---------------GIN 471
            ...|||.||.:|::.||:..|...:..::||...|..:| .:|..|:               ||.
  Rat   472 WLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYTVLGQLPDTDVYIDIDAYEEVKEIPGIK 536

  Fly   472 YILIRPKHSSLYFPAVEWVRSGISKALTIHGTAPVVLDCAHVHEFDFTAARGMGSLQKELAK--- 533
            ...|   ::.:|:...:...|.:.:..   |..|.::               ||:.:|.:.|
  Rat   537 IFQI---NAPIYYANSDLYSSALKRKT---GVNPAII---------------MGARRKAMRKYAK 580

  Fly   534 -------ANAPLFLMSAD---KTIGVILKESTNIDFPTI----DCPDDLEFLLEQ 574
                   |||.:..:.|:   :......:|...:.||.|    ..|::|:..|.|
  Rat   581 EVGNANIANATVVKVDAEVDGENATKPEEEDDEVKFPPIVIKTTFPEELQRFLPQ 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	SUL1	19..540	CDD:440424	152/586 (26%)
Slc26a5	NP_110467.1	PRK11660	66..709	CDD:481320	165/636 (26%)
		Involved in motor function. /evidence=ECO:0000250|UniProtKB:Q9JKQ2	158..168		1/9 (11%)
		Extended region for STAS domain. /evidence=ECO:0000269|PubMed:20471983, ECO:0007744|PDB:3LLO	505..718		27/152 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	720..744