DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6928 and slc26a3.1

DIOPT Version :9

Sequence 1:	NP_648539.1	Gene:	CG6928 / 39367	FlyBaseID:	FBgn0036240	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_001129155.1	Gene:	slc26a3.1 / 563962	ZFINID:	ZDB-GENE-041210-180	Length:	745	Species:	Danio rerio

Alignment Length:	722	Identity:	160/722 - (22%)
Similarity:	298/722 - (41%)	Gaps:	194/722 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLPGLKWLHGYTGQD-AVADLIAGVTVGLTVLPQGLAYATLAGLEPQYGLYSAFVGGIIYAMLGS 73
            |.|.:.|:..|..:: .:.|:::|::.||..:.||||::.||.|.|.||||:||...|||..||:
Zfish    68 LFPFIGWMKDYKIKEWLLGDIVSGISTGLVAVLQGLAFSLLASLPPGYGLYTAFFPAIIYFFLGT 132

  Fly    74 CRQVTIGPTALLALMTSR-HTGFGLGSGPAYAIL-----------------LCLISGVVELGMAV 120
            .|.:::|...:|:||... .|......||::.|.                 :..:.|..:|.|.:
Zfish   133 SRHLSVGAFPILSLMVGAVVTRLVPDEGPSFNITGFEGLSLEQQRVLVASSVTFLMGAFQLVMGL 197

  Fly   121 LKLGALVDLISLPVTVGFTSATAVIIGTSQLKGLLGLRGGSGSDF---------INTMRSVFGNL 176
            |::|.:|..:|..:..|||:|.||.|..|||:.:|||      ||         |.|:..||..:
Zfish   198 LQVGFIVMYLSETLVSGFTTAAAVHILVSQLRFVLGL------DFPGINGPLAIIYTLVEVFSRI 256

  Fly   177 HKVRTGDFTLGLTSIIVLLLLRKLKDVKLDGRIRNLRTQQLVSGSIWVIGTGRNALVVLVTSVLA 241
            ......|....:..:.::|:::::.|        ..:::..|...|.||.|     |:......|
Zfish   257 TSTNVADLVTSIAIMALVLIVKEIND--------RFKSKLPVPIPIEVIMT-----VIACGVSYA 308

  Fly   242 YSTCEQMESCPFILTGKVKSGLPNVSLPKFETTILDRNGTEIRQNFEQMLSELGPSMLILPIIAV 306
            ::..|:.:   .::.|::.:|..:...|..|.             .|:...|..|    :.|:..
Zfish   309 FNFEERFD---VVIVGEMVNGYESPVAPNLEV-------------IEETAVEAFP----MAIVGF 353

  Fly   307 LGNVAISKAFG---GAGLSPTRELVALSMSNICGAFCSSMPVTGSFSRSAVNHASGVRTPLGGCY 368
            ....:::|.:.   ...:...:||:|..:||:.||...|...:.:.||:|:..::|.:|.:.|..
Zfish   354 AVAFSVAKVYSVKHDYTIDGNQELIAFGVSNMFGASFRSFAASTALSRTAIQESTGGKTQIAGIL 418

  Fly   369 TSVLVLLALGLLAPYFQYIPKAALSA-VIISAVIFMIEFEVIKPLWRCSRRELLPGAITFVMSLA 432
            ::::||:.:..:....:.:|::.|.| ||::....:::|..:..|||..|.:.:...:||:.||.
Zfish   419 SAMMVLIVIVGVGFLLEPLPRSVLGALVIVNLKGMLMQFSELPFLWRNDRPDFVTWMVTFMASLF 483

  Fly   433 VGVEIGLLLGVSTDVAFLVYRAARPVLSVSKLQTTNGINYILIRPKHSSLY-------------- 483
            :|:::||.:|:..::..:|||...|..||  |...:|.:....|..::|:|
Zfish   484 LGLDLGLAVGIGAELFTVVYRTQFPRCSV--LANISGTDLYRDRKDYTSIYEPDGVKIFKIPSPI 546

  Fly   484 -FPAVEWVRSGI---------------SKAL---------------------------TIHGT-- 503
             |..:::.|..:               :|||                           |..|:
Zfish   547 FFANIDFFRDKLVQEVGFNPMRVLKKRNKALRKIRKMLCNGELEVSDRGPVLRQPSVDTSEGSME 611

  Fly   504 ---------------------------APV-----VLDCAHVHEFDFTAARGMGSLQKELAKANA 536
                                       .||     :||...|...|.:|.:|:.:..||..:...
Zfish   612 DLDQPIDFSDLPIQVNWNSQLPANISVPPVNIHSLILDFCAVSFIDVSALKGLKATLKEFIRIEV 676

  Fly   537 PLFLMSADKTIGVILKE--------STNIDFPTIDCPDDLEFLLEQTADYVLHLQISAPLVESRL 593
            .::::|.|..|...|:.        .|:|.:||:.             |.:||      ::|:
Zfish   677 DVYIVSCDVYIMEKLQHCTFFDDEIKTSIFYPTLH-------------DAMLH------ILET-- 720

  Fly   594 VHGDSGE 600
             |.|.||
Zfish   721 -HPDHGE 726

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	sulP	12..531	CDD:273284	142/641 (22%)
CG6928	NP_648539.1	STAS_SulP_like_sulfate_transporter	471..>540	CDD:132913	20/159 (13%)
slc26a3.1	NP_001129155.1	sulP	70..713	CDD:273284	151/696 (22%)
slc26a3.1	NP_001129155.1	STAS_SulP_like_sulfate_transporter	528..707	CDD:132913	25/178 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810