Protein Alignment CG6928 and SLC26A4

DIOPT Version :9

• Sequence 1: NP_648539.1
• Gene: CG6928 / 39367
• FlyBaseID: FBgn0036240
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_000432.1
• Gene: SLC26A4 / 5172
• HGNCID: 8818
• Length: 780
• Species: Homo sapiens
• Alignment Length: 756
• Identity: 164/756 - (21%)
• Similarity: 298/756 - (39%)
• Gaps: 228/756 - (30%)

  Fly    10 LLPGLKWLHGYTGQD-AVADLIAGVTVGLTVLPQGLAYATLAGLEPQYGLYSAFVGGIIYAMLGS 73
            |:|.|:||..|..:: .::|:|:||:.||....||:|||.||.:...|||||||...:.|.:.|:
Human    68 LVPILEWLPKYRVKEWLLSDVISGVSTGLVATLQGMAYALLAAVPVGYGLYSAFFPILTYFIFGT 132

  Fly    74 CRQVTIGPTALLALMT---------SRHTGFGLGSGPA-----------------YAILLCLISG 112
            .|.:::||..:::||.         ..|......:|..                 .|..|.|:.|
Human   133 SRHISVGPFPVVSLMVGSVVLSMAPDEHFLVSSSNGTVLNTTMIDTAARDTARVLIASALTLLVG 197

  Fly   113 VVELGMAVLKLGALVDLISLPVTVGFTSATAVIIGTSQLKGLLGL--RGGSG-SDFINTMRSVFG 174
            :::|....|::|.:|..::.|:..|||:|.|..:..||||.:|.:  :..:| ...|.|:..:|.
Human   198 IIQLIFGGLQIGFIVRYLADPLVGGFTTAAAFQVLVSQLKIVLNVSTKNYNGVLSIIYTLVEIFQ 262

  Fly   175 NLHKVRTGDFTLGLTSIIVLLLLRKLKDVKLDGRIRNLRTQQLVSGSIWVIGTGRNALVVLVTSV 239
            |:......|||.||.:|:|.:.:::|.|          |.:..:...|.:     ..:|.::.:.
Human   263 NIGDTNLADFTAGLLTIVVCMAVKELND----------RFRHKIPVPIPI-----EVIVTIIATA 312

  Fly   240 LAY-STCEQ------MESCPFILTGKVKSGLPNVSLPKFETTILDRNGTEIRQNFEQMLSELGPS 297
            ::| :..|:      ::|.|   .|.:...||.|||                  |.:||:    :
Human   313 ISYGANLEKNYNAGIVKSIP---RGFLPPELPPVSL------------------FSEMLA----A 352

  Fly   298 MLILPIIAVLGNVAISKAFG---GAGLSPTRELVALSMSNICGAFCSSMPVTGSFSRSAVNHASG 359
            ...:.::|....|::.|.:.   ...:...:|.:|..:|||...|.|....|.:.||:||..::|
Human   353 SFSIAVVAYAIAVSVGKVYATKYDYTIDGNQEFIAFGISNIFSGFFSCFVATTALSRTAVQESTG 417

  Fly   360 VRTPLGGCYTSVLVLLALGLLAPYFQYIPKAALSAVIISAV--IFMIEFEVIKPLWRCSRRELLP 422
            .:|.:.|..::.:|::|:..|....:.:.|:.|:||:|:.:  :|| :...|..|||.::.:.:.
Human   418 GKTQVAGIISAAIVMIAILALGKLLEPLQKSVLAAVVIANLKGMFM-QLCDIPRLWRQNKIDAVI 481

  Fly   423 GAITFVMSLAVGVEIGLLLGV-----------------------STDV--------------AFL 450
            ...|.::|:.:|:::|||.|:                       |||:              ...
Human   482 WVFTCIVSIILGLDLGLLAGLIFGLLTVVLRVQFPSWNGLGSIPSTDIYKSTKNYKNIEEPQGVK 546

  Fly   451 VYRAARPVL----------------------------SVSKLQ----------TTNGINYILIRP 477
            :.|.:.|:.                            ::.|:|          |.|||....:..
Human   547 ILRFSSPIFYGNVDGFKKCIKSTVGFDAIRVYNKRLKALRKIQKLIKSGQLRATKNGIISDAVST 611

  Fly   478 KHS-----------SLYFPA------VEW-----VRSGISKALTIHGTAPVVLDCAHVHEFDFTA 520
            .::           .|..|.      |:|     |:..:.| :.||.   :||||..:...|...
Human   612 NNAFEPDEDIEDLEELDIPTKEIEIQVDWNSELPVKVNVPK-VPIHS---LVLDCGAISFLDVVG 672

  Fly   521 ARGMGSLQKELAKANAPLFLMSADKTI-------------------------------------- 547
            .|.:..:.||..:.:..::..|....:
Human   673 VRSLRVIVKEFQRIDVNVYFASLQDYVIEKLEQCGFFDDNIRKDTFFLTVHDAILYLQNQVKSQE 737

  Fly   548 --GVILKESTNIDFPTIDCPDDLEFLLEQTADYVLHLQISA 586
              |.||:..|.|.    ||.|.||.:..:..:..|.:|..|
Human   738 GQGSILETITLIQ----DCKDTLELIETELTEEELDVQDEA 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	sulP	12..531	CDD:273284	148/657 (23%)
		STAS_SulP_like_sulfate_transporter	471..>540	CDD:132913	16/90 (18%)
SLC26A4	NP_000432.1	sulP	70..725	CDD:273284	150/699 (21%)
		STAS_SulP_like_sulfate_transporter	536..722	CDD:132913	25/189 (13%)
		Snf7	<583..654	CDD:304451	12/71 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910