DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6928 and CG9717

DIOPT Version :9

Sequence 1:	NP_648539.1	Gene:	CG6928 / 39367	FlyBaseID:	FBgn0036240	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_651812.1	Gene:	CG9717 / 43636	FlyBaseID:	FBgn0039789	Length:	638	Species:	Drosophila melanogaster

Alignment Length:	567	Identity:	219/567 - (38%)
Similarity:	336/567 - (59%)	Gaps:	19/567 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RKWGYRLLPGLKWLHGYTGQDAVADLIAGVTVGLTVLPQGLAYATLAGLEPQYGLYSAFVGGIIY 68
            :|..|:..|.|.||..|.......|::||::|.|||:||.||||.:|||:.|||||:.|:|..||
  Fly    66 KKTLYKRFPILVWLPQYKKDYIFGDIVAGISVALTVIPQALAYAGIAGLDLQYGLYACFLGCFIY 130

  Fly    69 AMLGSCRQVTIGPTALLALMTSRHTGFGLGSGPAYAILLCLISGVVELGMAVLKLGALVDLISLP 133
            ..:||.:.|.|||||:.||::.:..|   ||. ..|.||..::|::|:.|.|.:||.|:|.:|.|
  Fly   131 IFIGSSKDVPIGPTAISALLSFQIAG---GSW-QIATLLTFLTGLIEILMGVFRLGFLIDFVSGP 191

  Fly   134 VTVGFTSATAVIIGTSQLKGLLGLRGGSGSDFINTMRSVFGNLHKVRTGDFTLGLTSIIVLLLLR 198
            |..|||||.::||.:||:|..||:: .||:.|:....|:..::|.:...||.||:..|.:||.||
  Fly   192 VGAGFTSAVSLIIFSSQMKDFLGIK-TSGNTFLQVWISIVNDIHNISWPDFILGIVCITLLLSLR 255

  Fly   199 KLKDVKLDGRIRNLRTQQLVSGSIWVIGTGRNALVVLVTSVLAYSTCEQMESCPFILTGKVKSGL 263
            .|....|..:......|:|::|..|.|||.||||:|..|:.|.|......:.......|.|..||
  Fly   256 ALASCTLGPKEGKTTAQKLLTGIFWTIGTARNALLVCGTAGLGYWLFVNGKENLVKTVGFVPKGL 320

  Fly   264 PNVSLPKF--ETTILDRNGTEIR--QNFEQMLSELGPSMLILPIIAVLGNVAISKAFG-GAGLSP 323
            |:...|.|  :..:.:..|..::  |:|..|:|.||..::::|:||:|..:|:.:||. |.....
  Fly   321 PSFQPPPFHMDAVVNETTGEVLQEAQSFWDMVSTLGSGLIVVPLIALLETMAVVQAFADGKPTDA 385

  Fly   324 TRELVALSMSNICGAFCSSMPVTGSFSRSAVNHASGVRTPLGGCYTSVLVLLALGLLAPYFQYIP 388
            |:||:|..:.|:..:|...:...|..:|.|:.:||||||.|...||||:|::||..|.|.|.|||
  Fly   386 TQELIASGVCNVANSFVQGLRSNGGIARGAILNASGVRTQLSNLYTSVIVIIALLYLTPCFYYIP 450

  Fly   389 KAALSAVIISAVIFMIEFEVIKPLWRCSRRELLPGAITFVMSLAVGVEIGLLLGVSTDVAFLVYR 453
            ||||:::||:|||||:::.||||:|...:.:|:||...|...|.:.:::|:|:|:..:|.|::|:
  Fly   451 KAALASIIIAAVIFMVQYRVIKPMWHSKKTDLIPGLGAFFACLVLPLQLGILVGIGINVVFILYQ 515

  Fly   454 AARPVLSVSKLQTTNGINYILIRPKHSSLYFPAVEWVRSGISKALTIHG---TAPVVLDCAHVHE 515
            ||||.|.:..|.||.|:.|:::.|.. .|.||::|:||..|:|    .|   |.|||:||.|::.
  Fly   516 AARPKLRIETLATTTGLKYLMLTPDR-CLIFPSMEFVRKVINK----QGQKSTLPVVIDCTHIYG 575

  Fly   516 FDFTAARGMGSLQKELAKANAPLFLMSADKTIGVILKESTNIDFPTI 562
            .|||||:.:.::..:......|||..:....:..:. |..|.|...|
  Fly   576 ADFTAAKVISTMVMDFKLREQPLFFYNLQPRVAQVF-EGLNKDLVVI 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	sulP	12..531	CDD:273284	210/526 (40%)
CG6928	NP_648539.1	STAS_SulP_like_sulfate_transporter	471..>540	CDD:132913	25/71 (35%)
CG9717	NP_651812.1	sulP	74..607	CDD:273284	213/542 (39%)
CG9717	NP_651812.1	STAS_SulP_like_sulfate_transporter	534..612	CDD:132913	26/83 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439015
Domainoid	1	1.000	214	1.000	Domainoid score	I761
eggNOG	1	0.900	-	-		E1_COG0659
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1009
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55446
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		otm51364
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	P	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
	12	11.810