DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6928 and CG9702

DIOPT Version :9

Sequence 1:	NP_648539.1	Gene:	CG6928 / 39367	FlyBaseID:	FBgn0036240	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_001263113.1	Gene:	CG9702 / 43634	FlyBaseID:	FBgn0039787	Length:	676	Species:	Drosophila melanogaster

Alignment Length:	614	Identity:	229/614 - (37%)
Similarity:	359/614 - (58%)	Gaps:	52/614 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LPGLKWLHGYTGQDAVADLIAGVTVGLTVLPQGLAYATLAGLEPQYGLYSAFVGGIIYAMLGSCR 75
            ||.|.||..|..||.:.|||||.||||||:||||||:.:.||.|:||||.:|:|..:|.:||:|:
  Fly    78 LPFLTWLPHYNRQDCIGDLIAGFTVGLTVIPQGLAYSGVVGLPPEYGLYGSFMGCFVYVLLGTCK 142

  Fly    76 QVTIGPTALLALMTSRHTGFGLGSGPAYAILLCLISGVVELGMAVLKLGALVDLISLPVTVGFTS 140
            ..|||.||:.:|||.:   |..||... ::||..::|::|:.||:.|||.||:.:|.||:.||||
  Fly   143 DSTIGSTAVASLMTFQ---FAQGSWQR-SVLLTFLTGIIEILMAIFKLGCLVEFVSGPVSAGFTS 203

  Fly   141 ATAVIIGTSQLKGLLGLRGGSGSDFINTMRSVFGNLHKVRTGDFTLGLTSIIVLLLLRKLKDVKL 205
            |.|:|:.|||::.:||::...|| |:.|..|:|.::..||..|..||...:|:||.:|.|....:
  Fly   204 AVALIVSTSQMRSMLGVKSDGGS-FLATWISMFRDIENVRVADTCLGFGCVILLLAMRSLGKFTI 267

  Fly   206 DGRIRNLRT--QQLVSGSIWVIGTGRNA-LVVLVTSVLAYSTCEQMESCPFILTGKVKSGLPNVS 267
            ..:..:.|.  |::|:..|..:.|.||| :|:|.|:|..|  .:...:.||.|||.:..|:|..|
  Fly   268 GPKDESRRNGFQRVVNTVIKFLSTSRNASVVILFTAVTMY--LDANGTNPFRLTGNIPKGMPTPS 330

  Fly   268 LPKFETTILDRNGTEIR-------QNFEQMLSELGPSMLILPIIAVLGNVAISKAFG-GAGLSPT 324
            ||.|  :|..:.|.|..       |.|.:|:..||..::|:|::|:|..:::.|||. |..:..|
  Fly   331 LPPF--SIEPQPGNETAGIPAVEGQTFPEMVQSLGYGLVIVPLMALLETMSVCKAFAKGKQIDIT 393

  Fly   325 RELVALSMSNICGAFCSSMPVTGSFSRSAVNHASGVRTPLGGCYTSVLVLLALGLLAPYFQYIPK 389
            :|::|..:.||..:..|.....|..:|||||:|||.||.:...|..|:|:|||..|..|..:|||
  Fly   394 QEMIACGVGNIATSLFSGYRCNGGLARSAVNNASGCRTNMSNLYIGVIVVLALNFLTEYIAFIPK 458

  Fly   390 AALSAVIISAVIFMIEFEVIKPLWRCSRRELLPGAITFVMSLAVGVEIGLLLGVSTDVAFLVYRA 454
            |.|:|:|||||||.::::|:.|:||..|.:|:||.:.||..|.:.:|||:::.:..::.|::|.|
  Fly   459 AVLAAIIISAVIFQVQYQVVTPMWRSKRSDLVPGILAFVTCLVLPLEIGIMVAIGVNLLFILYYA 523

  Fly   455 ARPVLSVSKLQTTNGINYILIRPKHSSLYFPAVEWVRSGISKALTIHGTAPVVLDCAHVHEFDFT 519
            |||.:::.:|:|..||.::.|.|.. .|.||:||:||:.:.| |....|.|||:||.:::..|||
  Fly   524 ARPKVTLEQLETQQGIRFVKITPDR-CLIFPSVEFVRNMVLK-LGSKSTLPVVIDCTYIYAADFT 586

  Fly   520 AARGMGSLQKELAKANAPLFLMSADKTIGVILKESTNIDFPTIDC-----------PDDLEFLLE 573
            ||:.:.|:..:..:....:...:...:: |.:.|..|...  :.|           ||:.:  |.
  Fly   587 AAKVISSIVDDFRRRQQKIIFFNLKPSV-VSVFEGLNTRL--VLCYNTHALNQELRPDEPD--LS 646

  Fly   574 QTADYVLHLQISAPLVESRLVHGDSGEPT 602
            ::.|              .|.|.:||..|
  Fly   647 RSVD--------------SLDHAESGNGT 661

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	sulP	12..531	CDD:273284	215/529 (41%)
CG6928	NP_648539.1	STAS_SulP_like_sulfate_transporter	471..>540	CDD:132913	23/68 (34%)
CG9702	NP_001263113.1	SUL1	72..614	CDD:223732	216/546 (40%)
CG9702	NP_001263113.1	STAS_SulP_like_sulfate_transporter	531..619	CDD:132913	28/90 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439021
Domainoid	1	1.000	214	1.000	Domainoid score	I761
eggNOG	1	0.900	-	-		E1_COG0659
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1009
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55446
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		otm51364
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	P	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
	12	11.810