DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6928 and CG7912

DIOPT Version :9

Sequence 1:	NP_648539.1	Gene:	CG6928 / 39367	FlyBaseID:	FBgn0036240	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_651761.2	Gene:	CG7912 / 43561	FlyBaseID:	FBgn0039736	Length:	602	Species:	Drosophila melanogaster

Alignment Length:	600	Identity:	211/600 - (35%)
Similarity:	343/600 - (57%)	Gaps:	54/600 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 YRLLPGLKWLHGYTGQDAVADLIAGVTVGLTVLPQGLAYATLAGLEPQYGLYSAFVGGIIYAMLG 72
            :|.||...||..|.......|::||:|||||.:||.:||..:|.|.|.|||||||:||.:|.:||
  Fly    34 HRYLPVTDWLPKYQLNFLAMDVVAGLTVGLTAVPQAIAYGAVANLPPAYGLYSAFMGGFVYILLG 98

  Fly    73 SCRQVTIGPTALLALMTSRHTGFGLGSGPAYAILLCLISGVVELGMAVLKLGALVDLISLPVTVG 137
            :|:.:|:||||::|||...:    :...||||:|:|.:||.:...|.:|.||.|:..||:|||.|
  Fly    99 TCKDITVGPTAIMALMVQPY----VDGNPAYAVLICFLSGCIITLMGLLNLGVLMRFISVPVTTG 159

  Fly   138 FTSATAVIIGTSQLKGLLGLRGGSGSDFINTMRSVFGNLHKVRTGDFTLGLTSIIVLLLLRKLKD 202
            ||.|.|:.|.|.|:..|.|: ..|.|.|:|:....||::.:.|..|..||..::::|||:|:||:
  Fly   160 FTMAAALTIATGQVNSLFGI-SSSASGFLNSWIYFFGHITQTRRNDAILGCCTLVLLLLMRQLKN 223

  Fly   203 VKLDGRIRNLRTQQLVSGSIW-VIGTGRNALVVLVTSVLAYSTCEQMESCPFILTGKVKSGLPNV 266
            :....:            |:| .|...|||:.||:..:|.| ..:.....||:::|.:..|||..
  Fly   224 LTFGFK------------SVWKYISLARNAVAVLIGILLCY-LLKNDGKLPFLVSGSITPGLPPF 275

  Fly   267 SLPKFETTILDRNGTEIRQNFEQMLSELGPSMLILPIIAVLGNVAISKAFG-GAGLSPTRELVAL 330
            .||.|.|...:...|   .:|..|:|.:|.:::.:|::::|.::|::|||. |..:..::|::||
  Fly   276 KLPPFHTEDPETGET---ISFGGMVSNVGTALVSIPLLSILESIAVAKAFSKGKIVDASQEMIAL 337

  Fly   331 SMSNICGAFCSSMPVTGSFSRSAVNHASGVRTPLGGCYTSVLVLLALGLLAPYFQYIPKAALSAV 395
            .:|||..:|.||||:||||:|:|:|:||||:|||||..|..|||:.|..|...|.|||||.|:|:
  Fly   338 GVSNILSSFFSSMPITGSFTRTAINNASGVKTPLGGAVTGALVLMTLAFLTTTFAYIPKATLAAI 402

  Fly   396 IISAVIFMIEFEVIKPLWRCSRRELLPGAITFVMSLAVGVEIGLLLGVSTDVAFLVYRAARP--V 458
            ||:|:.||:|:|.|..:||..:|::||..:|.:..:...:|.|:::|:..:..||:|::.:|  .
  Fly   403 IIAAMFFMVEYETIGEIWRAKKRDMLPFLVTVLTCVFWTLEYGMVVGIVFNALFLLYKSMKPQFF 467

  Fly   459 LSVSKLQTTNGINYILIRPKHSSLYFPAVEWVRSGISKALT---IHGTAPVVLDCAHVHE---FD 517
            |:..|.   |||...:...| .|:.:.|.|:::..:...:|   ..|:||..|.....||   .|
  Fly   468 LTTEKF---NGIEVTMADLK-GSVDYAAAEYLKMSLVSHVTQRNSEGSAPTTLVVIKGHEIASID 528

  Fly   518 FTAARGMGSLQKELAKANAPLF-----------LMSADKTIGVILKESTNIDFPTIDCPDDLEFL 571
            .|.|..:.||:::||.....:.           :...|:.:..:.|.|.:.       ||.::.:
  Fly   529 TTVALNLKSLREDLALLKCDMICWNWSIPAAGVICRMDRKLRSMFKFSKSF-------PDLMQTI 586

  Fly   572 LE-QTADYVLHLQIS 585
            .: :.||..:.:.:|
  Fly   587 ADAEAADSCIAVDLS 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	sulP	12..531	CDD:273284	199/528 (38%)
CG6928	NP_648539.1	STAS_SulP_like_sulfate_transporter	471..>540	CDD:132913	18/85 (21%)
CG7912	NP_651761.2	sulP	38..542	CDD:273284	199/528 (38%)
CG7912	NP_651761.2	STAS	485..582	CDD:294402	21/103 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439032
Domainoid	1	1.000	214	1.000	Domainoid score	I761
eggNOG	1	0.900	-	-		E1_COG0659
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1009
Isobase	1	0.950	-	0	Normalized mean entropy	S2728
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		otm51364
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	P	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
	12	11.750