DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6928 and CG5404

DIOPT Version :9

Sequence 1:	NP_648539.1	Gene:	CG6928 / 39367	FlyBaseID:	FBgn0036240	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_650482.1	Gene:	CG5404 / 41901	FlyBaseID:	FBgn0038354	Length:	627	Species:	Drosophila melanogaster

Alignment Length:	594	Identity:	186/594 - (31%)
Similarity:	336/594 - (56%)	Gaps:	50/594 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LRKWGYRL---LPGLKWLHGYTGQDAVADLIAGVTVGLTVLPQGLAYATLAGLEPQYGLYSAFVG 64
            :.||..||   :|..:||..|:.:..:.|.|||:|:|||::|:.:|.|.||||..:|||.|||:|
  Fly    38 MNKWKRRLHRHVPVFQWLPLYSTEWGIDDFIAGITLGLTIIPESMACALLAGLPARYGLCSAFIG 102

  Fly    65 GIIYAMLGSCRQVTIGPTALLALMTSRHTGFGLGSGPAYAILLCLISGVVELGMAVLKLGALVDL 129
            .:||.:.||..:|.||||:|:||::.:   |.:|....:|.||..:||:|::.|..:::|.:.:.
  Fly   103 PLIYMVFGSIDKVIIGPTSLVALVSVQ---FTVGRPIEFAFLLTFLSGIVQIIMGTMRMGFIFEF 164

  Fly   130 ISLPVTVGFTSATAVIIGTSQLKGLLGLR---GGSGSDFINTMRSVFGNLHKVRTGDFTLGLTSI 191
            ||:||...|:||||:::..||||.|||::   .|    .:|::..:...:.:....|..:|:.:|
  Fly   165 ISMPVIKAFSSATAILVIESQLKVLLGIKYLVAG----LMNSVGMLSSRIEESNMADLIMGVCAI 225

  Fly   192 IVLLLLRKLKDVKLDGRIRNLRTQQLVSGSIWVIGTGRNALVVLVTSVLAYSTCEQMESCPFILT 256
            :.||||.     .||....|.:..:::......:.|.||.|:||:.:::::...::....|:.|:
  Fly   226 VFLLLLE-----LLDRVANNEKRNKILRIFCRYLSTSRNTLIVLIAAIVSFIWIQKCGQVPYALS 285

  Fly   257 GKVKSGLPNVSLPKFETTILDRNGTEIRQNFEQMLSELGPSMLILPIIAVLGNVAISKAFGGAGL 321
            ....|.|||.::|.|.....:||     .:..::|.||...::::||:.:|.|::|.|......:
  Fly   286 KNALSTLPNFTVPSFHIETAERN-----YSIWEVLKELNIGIIVIPIVGILTNISIGKLTPKGLV 345

  Fly   322 SPTRELVALSMSNICGAFCSSMPVTGSFSRSAVNHASGVRTPLGGCYTSVLVLLALGLLAPYFQY 386
            ...:||:.:.:.|:.|:...:||.:|:|:|.|::.|.|:|||:...|..::|||||..|:|||.|
  Fly   346 DTNQELLTVGLCNMFGSCVQAMPSSGAFTRYAISTACGLRTPMANLYLGIIVLLALSYLSPYFNY 410

  Fly   387 IPKAALSAVIISAVIFMIEFEVIKPLWRCSRRELLPGAITFVMSLAVGVEIGLLLGVSTDVAFLV 451
            ||:|.|:|::|.::..:::|::...|||.|:|:.....:.|.:|:..|||:||.:.:......|:
  Fly   411 IPEATLAAILICSIFTLLDFKLPMRLWRDSKRDFATWLLCFCVSVLFGVEVGLFVSIVVTALHLL 475

  Fly   452 YRAARPVLSVSKLQTTNGINYILIRPKHSSLYFPAVEWVRSGISKA-------LTIHGTAPVVLD 509
            :..|||.:.| |::..:.:.||.:.|. :.:||||:.::|..:.||       :|      ||:|
  Fly   476 FLWARPEIRV-KIEQLDEMQYIRVTPS-NGIYFPAINYLRERVLKACEQADFRIT------VVID 532

  Fly   510 CAHVHEFDFTAARGMGSLQKEL-----AKANAPLFLMSADKTIGVILKESTNIDFPTIDCPDD-- 567
            ...:...|:|||:|:..|..:|     |.::..|.|....:.:..::..:.|:.|    |..:
  Fly   533 GQRISGMDYTAAQGISKLSSDLCRQADASSSTLLILFRFPEHLQRLIDNTDNLVF----CESENK 593

  Fly   568 -LEFLLEQT 575
             .|||.:::
  Fly   594 VKEFLTQES 602

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	sulP	12..531	CDD:273284	172/528 (33%)
CG6928	NP_648539.1	STAS_SulP_like_sulfate_transporter	471..>540	CDD:132913	23/80 (29%)
CG5404	NP_650482.1	sulP	50..557	CDD:273284	173/531 (33%)
CG5404	NP_650482.1	STAS_SulP_like_sulfate_transporter	498..>554	CDD:132913	18/62 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439008
Domainoid	1	1.000	214	1.000	Domainoid score	I761
eggNOG	1	0.900	-	-		E1_COG0659
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1009
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		otm51364
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
	10	9.900