Protein Alignment CG6928 and Prestin

DIOPT Version :9

• Sequence 1: NP_648539.1
• Gene: CG6928 / 39367
• FlyBaseID: FBgn0036240
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_649024.1
• Gene: Prestin / 39996
• FlyBaseID: FBgn0036770
• Length: 742
• Species: Drosophila melanogaster
• Alignment Length: 711
• Identity: 164/711 - (23%)
• Similarity: 277/711 - (38%)
• Gaps: 197/711 - (27%)

  Fly     4 RKWGY-----RLLPGLKWLHGYT-GQDAVADLIAGVTVGLTVLPQGLAYATLAGLEPQYGLYSAF 62
            |.|.:     .::|.|:||..|: .:|...|:|||.||.:..:|.|:||..|||:....|||.|.
  Fly    69 RSWNFFALFTGVIPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYGILAGVSAGNGLYMAV 133

  Fly    63 VGGIIYAMLGSCRQVTIGPTALLALMTSR-----------H-----TGFGLGS-GPAYAILLCLI 110
            ...:.|..||:.:.::||..|:.::||::           |     ..|||.| |.|.|..|.||
  Fly   134 FPVLAYMFLGTSKHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQSNGTATASPLLLI 198

  Fly   111 S-----------------------------------------GVVELGMAVLKLGALVDLISLPV 134
            :                                         |:|.|.||.|:||.|..|:|.|:
  Fly   199 NSSALADSVSSTTISPFQLLNSTLNADPITKIEVATSLALTVGIVNLLMAFLRLGTLSSLLSEPL 263

  Fly   135 TVGFTSATAVIIGTSQLKGLLGL---RGGSGSDFINTMRSVFGNLHKVRTGDFTLGLTSIIVLLL 196
            ..|||:|.|..:.|:|||.:||:   |.......|.|:..|...:.:....:|...:..|..:::
  Fly   264 VNGFTTAAACHVVTAQLKDVLGISVPRHKGAFKIIYTVIDVIKGVPQTNLVNFGFCMAVIAFMMI 328

  Fly   197 LRKLKDVKLDGRIRNLRTQQLVSGSIWVIGTGRNALVVLVTS----VLAYSTCEQMESCPFILTG 257
            ..::...:|..:.|.....:|    |.|||.      .|::.    .:.|:...         .|
  Fly   329 CNEILKPRLSKKCRFPLPAEL----IMVIGG------TLISKWFNLYVDYNVNP---------VG 374

  Fly   258 KVKSGLPNVSLPKFETTILDRNGTEIRQNFEQMLSELGPSMLILPIIAVLGNVAISKAFG----- 317
            |:.||||...||:.                     :|.|.:.:..|...:...:|..:.|
  Fly   375 KIPSGLPEPVLPRL---------------------DLVPKVAVDSIAIAIVTYSIIMSMGLTFAK 418

  Fly   318 --GAGLSPTRELVALSMSNICGAFCSSMPVTGSFSRSAVNHASGVRTPLGGCYTSVLVLLALGLL 380
              |..:.|.:||.|:.:.|:.|...|.:|:..|.|||.:...:|..:.:....::.||::.|..:
  Fly   419 KHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSLSRSVIQDQTGGVSQIASLVSASLVVVTLMWI 483

  Fly   381 APYFQYIPKAALSAVIISAV--IFMIEFEVIKPLWRCSRRELLPGAITFVMSLAVGVEIGLLLGV 443
            .|:|..:|:..|:.|||.|:  :|| :.:.:|...:..:.|:.....||:..:.:.::||||:|:
  Fly   484 GPFFSSLPRCVLAGVIIVALKPMFM-QAKELKKFSKQGKLEMFTWISTFLCVVIIDIDIGLLIGI 547

  Fly   444 STDVAFLVYRAARP--------------------------VLSVSKLQTTNGINYILIRPKHSSL 482
            ...:..|..:..:|                          |..|...:.:..:|:.      :||
  Fly   548 CISLLALYIKGLKPYSCLLGYMPEAPGIYMDLNQHRNAMQVPEVRIFRYSGSLNFA------TSL 606

  Fly   483 YF-----PAVEWVRSGISKALTIHGTAP--------------------------------VVLDC 510
            :|     .||...:..::|..:.:..:|                                :|||.
  Fly   607 FFRRALYEAVGLDKIPLTKVSSSNSNSPSKGSKSSYSPVSQNGGKAINGKLEETSGAFKVLVLDF 671

  Fly   511 AHVHEFDFTAARGMGSLQKELAKANAPLFLMS-ADKTIGVI-----LKESTNIDFPTI-DC 564
            :.:...|....|.:..|.|||....|.|.|.| .|:....:     |.|.....|||: ||
  Fly   672 SMLGHIDVAGCRTLTDLSKELKVRGARLLLASPVDRVYDTLVHSMALSEGPFEIFPTLHDC 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	sulP	12..531	CDD:273284	148/656 (23%)
		STAS_SulP_like_sulfate_transporter	471..>540	CDD:132913	19/105 (18%)
Prestin	NP_649024.1	sulP	82..731	CDD:273284	160/695 (23%)
		STAS_SulP_like_sulfate_transporter	582..730	CDD:132913	29/153 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439038
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	P	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
	7	6.740