DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6928 and slc26a11

DIOPT Version :9

Sequence 1:	NP_648539.1	Gene:	CG6928 / 39367	FlyBaseID:	FBgn0036240	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_956061.1	Gene:	slc26a11 / 327138	ZFINID:	ZDB-GENE-030131-5349	Length:	572	Species:	Danio rerio

Alignment Length:	592	Identity:	229/592 - (38%)
Similarity:	327/592 - (55%)	Gaps:	56/592 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PGLKWLHGYTGQDAVADLIAGVTVGLTVLPQGLAYATLAGLEPQYGLYSAFVGGIIYAMLGSCRQ 76
            |.:.||..|.......|:|||:|||||.:||.||||.:|||..||||||||:||.||.:.|:.:.
Zfish    16 PIITWLPRYNLTWLKMDVIAGLTVGLTAVPQALAYAEVAGLPVQYGLYSAFMGGFIYCIFGTSKD 80

  Fly    77 VTIGPTALLALMTSRH-TGFGLGSGPAYAILLCLISGVVELGMAVLKLGALVDLISLPVTVGFTS 140
            :|:||||:::|:.|.: ||     .|.:|::|.|:.||::.|||:|:||.|:|.||.||..|||.
Zfish    81 ITLGPTAIMSLLCSSYITG-----DPVFAVVLTLLCGVIQTGMALLRLGFLLDFISYPVIKGFTC 140

  Fly   141 ATAVIIGTSQLKGLLGLRGGSGSDFINTMRSVFGNLHKV---RTGDFTLGLTSIIVLLLLRKLKD 202
            |.||.||..|:|.:|||:......|:    .|:...||:   |.||..|||:.:..||:|..:|:
Zfish   141 AAAVTIGFGQVKNILGLKEIPQQFFL----QVYYTFHKIPEARVGDVILGLSCLFFLLILTFMKN 201

  Fly   203 VKLDGR-------IRNLRTQQLVSGSIWVIGTGRNALVVLVTSVLAYSTCEQMESCPFILTGKVK 260
             .|:..       :|:.|  ||    :|.:.|.||||||:..:.:|:| .|...:..|.||||..
Zfish   202 -SLNSAEDEASFLVRSAR--QL----LWSLATIRNALVVIAAAGVAFS-AEVTGNHFFSLTGKTA 258

  Fly   261 SGLPNVSLPKFETTILDRNGTEIRQNFEQMLSELGPSMLILPIIAVLGNVAISKAFGGAG---LS 322
            .|||....|....||  .|||.|  .|..:..:||..:.::|::.||.::||:||||...   :.
Zfish   259 KGLPPFRAPPLSETI--ANGTVI--TFSDIAKDLGGGLAVIPLMGVLESIAIAKAFGSKNNYRID 319

  Fly   323 PTRELVALSMSNICGAFCSSMPVTGSFSRSAVNHASGVRTPLGGCYTSVLVLLALGLLAPYFQYI 387
            ..:||.|:.::||.|:|.|:.||||||.|:|||..:||.:|.||..|||:|||:|..|.|.|.||
Zfish   320 ANQELFAIGLTNIMGSFVSAYPVTGSFGRTAVNSQTGVCSPAGGIITSVIVLLSLAFLMPLFFYI 384

  Fly   388 PKAALSAVIISAVIFMIEFEVIKPLWRCSRRELLPGAITFVMSLAVGVEIGLLLGVSTDVAFLVY 452
            |||:|:||||.||..|::|.|...:||..|.:|||..:||::|. ..|:.|:..||......|:|
Zfish   385 PKASLAAVIICAVSPMVDFRVPLHIWRVKRLDLLPFLVTFLLSF-WEVQYGIAGGVLVSAFMLLY 448

  Fly   453 RAARPVLSVSK-----LQTTNGINYILIRPKHSSLYFPAVEWVRSGISKALTIHGTAP--VVLDC 510
            ..|||.:.||.     |:..||:|            |.:.|.:...:.|. .:|.:.|  :||||
Zfish   449 IMARPKVKVSDHGVIVLEIDNGLN------------FTSTEHLSRLVYKH-ALHASPPRSLVLDC 500

  Fly   511 AHVHEFDFTAARGMGSLQKELAKANAPLFLMSADKTIGVILKESTNIDFPTIDCPDDLEFLLEQT 575
            :.:...|||....:..|.|:.....|.|.......::..:|..:....|...|..|:...||...
Zfish   501 SQISSIDFTVIHELTDLLKQFQIRGAALIFTGLKPSVLQVLLLADLPAFRHTDTVDEALQLLTAN 565

  Fly   576 ADYVLHL 582
            ..|..||
Zfish   566 IHYNQHL 572

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	sulP	12..531	CDD:273284	218/539 (40%)
CG6928	NP_648539.1	STAS_SulP_like_sulfate_transporter	471..>540	CDD:132913	17/70 (24%)
slc26a11	NP_956061.1	sulP	16..541	CDD:273284	220/559 (39%)
slc26a11	NP_956061.1	STAS_SulP_like_sulfate_transporter	454..546	CDD:132913	23/104 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574463
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.710