DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6928 and Slc26a8

DIOPT Version :9

Sequence 1:	NP_648539.1	Gene:	CG6928 / 39367	FlyBaseID:	FBgn0036240	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	XP_038954621.1	Gene:	Slc26a8 / 309646	RGDID:	1308898	Length:	1006	Species:	Rattus norvegicus

Alignment Length:	529	Identity:	115/529 - (21%)
Similarity:	216/529 - (40%)	Gaps:	105/529 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLPGLKWLHGYTGQD-AVADLIAGVTVGLTVLPQGLAYATLAG--LEPQYGLYSAFVGGIIYAML 71
            :.|.|:|:..|..:| .:.||:||::|||..:||||..:.|..  :.|....|:||...:||.:.
  Rat    74 VFPFLEWMCLYRFKDWLLGDLLAGLSVGLVQVPQGLTLSLLTRQLIPPLNVAYAAFCSSVIYVIF 138

  Fly    72 GSCRQVTIGPTALL-ALMTS--RHTGFGLG------------SGPAYAI----------LLCLIS 111
            |||.|::|||..|: |||.:  :...|..|            |.|.:.:          ....::
  Rat   139 GSCHQMSIGPFFLVSALMINVLKERPFNNGHLIMGTFVKDDFSVPTFYLNYNRSLSMVASTTFLT 203

  Fly   112 GVVELGMAVLKLGALVDLISLPVTVGFTSATAVIIGTSQLKGLLGL----RGGSGSDFINTMRSV 172
            |:::|.|.:|.:|.:...:....|..:.:|.|:.|..:|:..:.|:    ..|..:...|.:...
  Rat   204 GIIQLSMGMLGMGFVATYLPEAATSAYLAAVALHIILAQMTCIFGIMVSFHAGPIAFIYNIINYC 268

  Fly   173 FGNLHKVRTGDFTLGLTSIIVLLLLRKLKDVKLDGRIRNLRTQQLVSGSIWVIGTGRNALVVLVT 237
            .. |.|..:....|.||:::.|.:.:.::                :|.:.:.|......|::|..
  Rat   269 IA-LPKANSTSILLFLTAVVALRVNKCIR----------------ISFNRYPIEFPMELLLILGF 316

  Fly   238 SVLAYSTCEQMESCPFILTGKVKSGLPNVSLPKF---ETTILDRNGTEIRQNFEQMLSELGPSML 299
            |:|........|:.. :|...:.........|:|   ...:|......:..:|  :|..||..
  Rat   317 SMLTSRITMATENSK-MLINMIPYSFVFPETPEFGILSRIVLQALSLSVVSSF--LLISLGKK-- 376

  Fly   300 ILPIIAVLGNVAISKAFGGAGLSPTRELVALSMSNICGAFCSSMPVTGSFSRSAVNHASG----- 359
                ||.|.|...:.         .::|:|:.:.|:..:|......||..:|:.:...||
  Rat   377 ----IANLHNYRTNS---------NQDLIAIGLCNLVSSFFRCCVFTGGMARTIIQDKSGGRQQK 428

  Fly   360 ------------VRTPLGGCYTSVL----------------VLLALGLLAPYFQYIPKAALSAVI 396
                        ::|....|.|..|                :||.:..:..:|..:|.|.|:.:|
  Rat   429 KLACFSANRRPQLQTGTNACLTRSLQPALSPQFASLVGAGVMLLLMVKIGSFFDNLPNAVLAGII 493

  Fly   397 ISAVIFMIEFEVIKP-LWRCSRRELLPGAITFVMSLAVGVEIGLLLGVSTDVAFLVYRAAR-PVL 459
            :|.|:..:|.....| |||..:.|.:...:||..::.:|:::|||:.:......:..|:.| .:|
  Rat   494 LSNVVPYLETIYNLPTLWRQDQYECVVWMVTFSAAIFLGLDVGLLISLVFTFFVITVRSHRTKIL 558

  Fly   460 SVSKLQTTN 468
            .:.::..||
  Rat   559 VLGQIPNTN 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	sulP	12..531	CDD:273284	115/527 (22%)
CG6928	NP_648539.1	STAS_SulP_like_sulfate_transporter	471..>540	CDD:132913
Slc26a8	XP_038954621.1	Sulfate_transp	90..524	CDD:395733	99/468 (21%)
Slc26a8	XP_038954621.1	STAS_SulP_like_sulfate_transporter	<730..805	CDD:132913
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920