DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6928 and Slc26a6

DIOPT Version :9

Sequence 1:	NP_648539.1	Gene:	CG6928 / 39367	FlyBaseID:	FBgn0036240	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_001137289.1	Gene:	Slc26a6 / 301010	RGDID:	1310197	Length:	758	Species:	Rattus norvegicus

Alignment Length:	474	Identity:	130/474 - (27%)
Similarity:	232/474 - (48%)	Gaps:	57/474 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LPGLKWLHGYTGQD-AVADLIAGVTVGLTVLPQGLAYATLAGLEPQYGLYSAFVGGIIYAMLGSC 74
            :|.|.||..|..:: .:.||::|::|.:..||||||||.||||.|.:||||:|....:|.:.|:.
  Rat    77 VPVLGWLPRYPVREWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPMFGLYSSFYPVFVYFLFGTS 141

  Fly    75 RQVTIGPTALLALMTSRHTGFGLGSGPAY---------------AILLCLISGVVELGMAVLKLG 124
            |.:::|..|::::|....|. .|.:..|:               |..|..:.|:.::|:.::..|
  Rat   142 RHISVGTFAVMSVMVGGVTE-SLTADEAFVQSLNTTVDGARVQVAYTLSFLVGLFQVGLGLVHFG 205

  Fly   125 ALVDLISLPVTVGFTSATAVIIGTSQLKGLLGLRGGSGS---DFINTMRSVFGNLHKVRTGDFTL 186
            .:|..:|.|:...:|:|.:|.:..||||.:.|::..|.|   ..|.|:..|...|.|...|....
  Rat   206 FVVTYLSEPLVRSYTTAASVQVLVSQLKYVFGIKLNSHSGPLSVIYTVLEVCAQLPKTVPGTVVT 270

  Fly   187 GLTSIIVLLLLRKLKDVKLDGRIRNLRTQQLVSGSIWVIGTGRNALVVLVTSVLAYSTCEQMESC 251
            .:.:.:||:|::.|.:     ::|. |....:.|.:         |.::..:.::|.. :..:..
  Rat   271 AIVAGVVLVLVKLLNE-----KLRR-RLPLPIPGEL---------LTLIGATAISYGV-KLNDRF 319

  Fly   252 PFILTGKVKSGLPNVSLPKFETTILDRNGTEIRQNFEQMLSELGPSMLILPIIAVLGNVAISKAF 316
            ...:.|.:.:||.....||.|                 :.:.|..:...:.::.....:::.|.|
  Rat   320 KVDVVGNITTGLIPPVAPKTE-----------------LFATLVGNAFAIAVVGFAIAISLGKIF 367

  Fly   317 G---GAGLSPTRELVALSMSNICGAFCSSMPVTGSFSRSAVNHASGVRTPLGGCYTSVLVLLALG 378
            .   |..:...:|||||.:||:.|.|....||:.|.|||.|..::|..|.:.|..:|:.:||.:.
  Rat   368 ALRHGYRVDSNQELVALGLSNLIGGFFQCFPVSCSMSRSLVQESTGGNTQIAGAVSSLFILLIIV 432

  Fly   379 LLAPYFQYIPKAALSAVIISAVIFMI-EFEVIKPLWRCSRRELLPGAITFVMSLAVGVEIGLLLG 442
            .|...|:.:|||.|:||||..:..|: :|..|..||:.:|.:||...:|||.::.:.::|||.:.
  Rat   433 KLGELFRDLPKAVLAAVIIVNLKGMMKQFSDICSLWKANRVDLLIWLVTFVATILLNLDIGLAVS 497

  Fly   443 VSTDVAFLVYRAARPVLSV 461
            :...:..:|.|...|..||
  Rat   498 IVFSLLLVVIRMQLPHYSV 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	sulP	12..531	CDD:273284	130/473 (27%)
CG6928	NP_648539.1	STAS_SulP_like_sulfate_transporter	471..>540	CDD:132913
Slc26a6	NP_001137289.1	sulP	78..737	CDD:273284	130/473 (27%)
		HCO3_cotransp	<369..452	CDD:304903	32/82 (39%)
		STAS_SulP_like_sulfate_transporter	<653..734	CDD:132913
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.710