DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6928 and Slc26a7

DIOPT Version :9

Sequence 1:	NP_648539.1	Gene:	CG6928 / 39367	FlyBaseID:	FBgn0036240	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	XP_038965346.1	Gene:	Slc26a7 / 297910	RGDID:	1310846	Length:	692	Species:	Rattus norvegicus

Alignment Length:	595	Identity:	145/595 - (24%)
Similarity:	264/595 - (44%)	Gaps:	94/595 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LRKWGYRLLPGLKWLHGYT-GQDAVADLIAGVTVGLTVLPQGLAYATLAGLEPQYGLYSAFVGGI 66
            :::|..|.||.|:|...|. .::.:.|.::||.:.:..:.|||::|.|:.:.|.:|||.:....|
  Rat    24 IKQWCKRRLPILEWAPQYNLKENLLPDTVSGVLLAVQQVTQGLSFAILSSVHPVFGLYGSLFPAI 88

  Fly    67 IYAMLGSCRQVTIGPTALLALMT------------------SRHTGFGLGS------GPAYAILL 107
            |||:.|..|.|..|..||.:|::                  |..:..||..      |.|.|:
  Rat    89 IYAIFGMGRHVATGTFALTSLISANAVERLVPQSNRNLTTQSNSSVLGLSEFELQRIGVAAAV-- 151

  Fly   108 CLISGVVELGMAVLKLGALVDLISLPVTVGFTSATAVIIGTSQLKGLLGLR-----GGSGSDFIN 167
            ..:.||::|.|.||:||....|::.||....|:..|..:.|||:|.|||::     |..|  |..
  Rat   152 SFLGGVIQLVMFVLQLGNATFLLTEPVISAMTTGAATHVVTSQVKYLLGIKMPYISGPLG--FFY 214

  Fly   168 TMRSVFGNLHKVRTGDFTLGLTSIIVLLLLRKLKDVKLDGRIRNLRTQQLVSGSIWVIGTGRNAL 232
            ....||.|:..|:.....|.|.||:||:|:::|.: :...:|:.:....||
  Rat   215 IYAYVFENIKSVQLEALLLSLLSIVVLVLVKELNE-QFKRKIKVVLPVDLV-------------- 264

  Fly   233 VVLVTSVLAYSTCEQMESCPFI-LTGKVKSGLPNVSLPKFETTILDRNGTEIRQNFEQMLSELGP 296
            :::..|...|  |..||:...: :.|::..|:|....|..  .||....||          ..|
  Rat   265 LIIAASFACY--CTNMENTYGLEVVGRIPKGIPPPRAPPM--NILSAVLTE----------AFG- 314

  Fly   297 SMLILPIIAVLGNVA-ISKAFGGA-----GLSPTRELVALSMSNICGAFCSSMPVTGSFSRSAVN 355
                   :|::|.|| ::.|.|.|     .:...:|.:|..:||:..:|...:|...:..|:|..
  Rat   315 -------VALVGYVASLALAQGSAKKFKYSVDDNQEFLAHGLSNVIPSFLFCIPSAAAMGRTAGL 372

  Fly   356 HASGVRTPLGGCYTSVLVLLALGLLAPYFQYIPKAALSAVIISAVI-FMIEFEVIKPLWRCSRRE 419
            :::|.:|.:....:.:.||:.:..:.|...::|...|:::|:..:. .:|:|..:|..|...:.:
  Rat   373 YSTGAKTQVACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKID 437

  Fly   420 LLPGAITFVMSLAVGVEIGLLLGVSTDVAFLVYRAAR-PVLSVSKLQTTNGINYILIRPKHSSLY 483
            ......|::.::.....:|||.||...:|.::.|..| ..||::.::...      ::.| :..|
  Rat   438 WGIWISTYIFTICFAANVGLLFGVVCTIAIVLGRFPRAKTLSITDMKEME------LKVK-TETY 495

  Fly   484 FPAVEWVRSGISKALTIHGTAPVVLDCAHVHEFDFTAARGMGSLQKELAKANAPLFLMSADK--- 545
            .....|..|..:......|:   :...::|.....|..|...|.|.::...|.||..::|.|
  Rat   496 DNTENWPPSKSTNVKVFPGS---LKTGSNVRSLSVTPRRMENSQQIKIISINNPLVFLNAKKFSA 557

  Fly   546 -TIGVILKES 554
             .:.:||||:
  Rat   558 DLMKIILKET 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	sulP	12..531	CDD:273284	133/557 (24%)
CG6928	NP_648539.1	STAS_SulP_like_sulfate_transporter	471..>540	CDD:132913	13/68 (19%)
Slc26a7	XP_038965346.1	sulP	33..673	CDD:273284	142/586 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810