Protein Alignment CG6928 and Slc26a4

DIOPT Version :10

• Sequence 1: NP_648539.1
• Gene: CG6928 / 39367
• FlyBaseID: FBgn0036240
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_062087.1
• Gene: Slc26a4 / 29440
• RGDID: 3293
• Length: 780
• Species: Rattus norvegicus
• Alignment Length: 747
• Identity: 175/747 - (23%)
• Similarity: 309/747 - (41%)
• Gaps: 208/747 - (27%)

  Fly    10 LLPGLKWLHGYTGQD-AVADLIAGVTVGLTVLPQGLAYATLAGLEPQYGLYSAFVGGIIYAMLGS 73
            |||.|.||..|..:: .::|:|:||:.||....||:|||.||.:..||||||||...:.|.:.|:
  Rat    68 LLPILDWLPKYRVKEWLLSDIISGVSTGLVGTLQGMAYALLAAVPVQYGLYSAFFPILTYFVFGT 132

  Fly    74 CRQVTIGPTALLALM----------------------TSRHTGFGLGSGPAYAILLC----LISG 112
            .|.:::||..:::||                      |...|....|:..|..:||.    |:.|
  Rat   133 SRHISVGPFPVVSLMVGSVVLSMAPDDHFLVPSGNGSTLNTTTLDTGTRDAARVLLASTLTLLVG 197

  Fly   113 VVELGMAVLKLGALVDLISLPVTVGFTSATAVIIGTSQLKGLLGL--RGGSG-SDFINTMRSVFG 174
            :::|....|::|.:|..::.|:..|||:|.|..:..||||.:|.:  :..:| ...|.|:..:|.
  Rat   198 IIQLVFGGLQIGFIVRYLADPLVGGFTTAAAFQVLVSQLKIVLNVSTKNYNGVLSIIYTLIEIFQ 262

  Fly   175 NLHKVRTGDFTLGLTSIIVLLLLRKLKDVKLDGRIRNLRTQQLVSGSIWVIGTGRNALVVLVTSV 239
            |:......||..||.:|||.:.:::|.|          |.:..:...|.:     ..:|.::.:.
  Rat   263 NIGDTNIADFIAGLLTIIVCMAVKELND----------RFKHKIPVPIPI-----EVIVTIIATA 312

  Fly   240 LAYSTCEQ-------MESCPFILTGKVKSGLPNVSLPKFETTILDRNGTEIRQNFEQMLSELGPS 297
            ::|....:       ::|.|   :|.:...||:|.|                  |..||:    :
  Rat   313 ISYGANLEANYNAGIVKSIP---SGFLPPVLPSVGL------------------FSDMLA----A 352

  Fly   298 MLILPIIAVLGNVAISKAFGGAG---LSPTRELVALSMSNICGAFCSSMPVTGSFSRSAVNHASG 359
            ...:.::|....|::.|.:....   :...:|.:|..:||:...|.|....|.:.||:||..::|
  Rat   353 SFSIAVVAYAIAVSVGKVYATKHDYIIDGNQEFIAFGISNVFSGFFSCFVATTALSRTAVQESTG 417

  Fly   360 VRTPLGGCYTSVLVLLALGLLAPYFQYIPKAALSAVIISAV--IFMIEFEVIKPLWRCSRRELLP 422
            .:|.:.|..::|:|::|:..|....:.:.|:.|:||:|:.:  :||...:|.: ||:.::.:.:.
  Rat   418 GKTQVAGLISAVIVMVAIVALGKLLEPLQKSVLAAVVIANLKGMFMQVCDVPR-LWKQNKTDAVI 481

  Fly   423 GAITFVMSLAVGVEIGLLLGV-----------------------STDV----------------- 447
            ...|.:||:.:|:::|||.|:                       |||:
  Rat   482 WVFTCIMSIILGLDLGLLAGLLFGLLTVVLRVQFPSWNGLGSVPSTDIYKSITHYKNLEEPEGVK 546

  Fly   448 ---------------------------AFLVY-------RAARPVLSVSKLQTT-NGINYILIRP 477
                                       |..||       |..:.::...:|:.| |||    |..
  Rat   547 ILRFSSPIFYGNVDGFKKCVKSTVGFDAIRVYNKRLKALRRIQKLIKKGQLRATKNGI----ISD 607

  Fly   478 KHSS---------------LYFPA------VEW-----VRSGISKALTIHGTAPVVLDCAHVHEF 516
            ..||               |..|.      |:|     |:..:.| :.||.   :||||..|...
  Rat   608 VGSSNNAFEPDEDVEEPEELDIPTKEIEIQVDWNSELPVKVNVPK-VPIHS---LVLDCGAVSFL 668

  Fly   517 DFTAARGMGSLQKELAKANAPLF--LMSADKTIGVILKESTNIDFPTIDCPDDLEFLLEQTADYV 579
            |....|.:..:.||..:.:..::  |:..|     :|::.....|...:...|..||  ...|.:
  Rat   669 DVVGVRSLRMIVKEFQRIDVNVYFALLQDD-----VLEKMEQCGFFDDNIRKDRFFL--TVHDAI 726

  Fly   580 LHLQISA-------PLVESRLVHGDSGEPTEL 604
            |:||..|       .|:|:..:..|..:|.||
  Rat   727 LYLQNQAKSREGQDSLLETITLIQDCKDPLEL 758

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	SUL1	19..540	CDD:440424	151/665 (23%)
Slc26a4	NP_062087.1	PRK11660	70..725	CDD:481320	162/710 (23%)