DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6928 and Slc26a8

DIOPT Version :9

Sequence 1:	NP_648539.1	Gene:	CG6928 / 39367	FlyBaseID:	FBgn0036240	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	XP_011244686.1	Gene:	Slc26a8 / 224661	MGIID:	2385046	Length:	1027	Species:	Mus musculus

Alignment Length:	515	Identity:	115/515 - (22%)
Similarity:	216/515 - (41%)	Gaps:	110/515 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLPGLKWLHGYTGQD-AVADLIAGVTVGLTVLPQGLAYATLAG--LEPQYGLYSAFVGGIIYAML 71
            :.|.|:|:..|..:| .:.||:||::|||..:||||..:.|..  :.|....|:||...:||.:.
Mouse   102 VFPFLEWICLYRFKDWLLGDLLAGLSVGLVQVPQGLILSLLTRQLIPPLNVTYAAFCSSVIYVIF 166

  Fly    72 GSCRQVTIGPTALL-ALMTS--RHTGFGLG------------SGPAYAI----------LLCLIS 111
            |||.|::|||..|: |||.:  :...|..|            |.|.:.:          ....::
Mouse   167 GSCHQMSIGPFFLVSALMINVLKDRPFNNGHLILGTFVKDDFSVPTFYLSYNRSLSMVASTTFLT 231

  Fly   112 GVVELGMAVLKLGALVDLISLPVTVGFTSATAVIIGTSQLKGLLGL----RGGSGSDFINTMRSV 172
            |:::|.|.:|.:|.:...:....|..:.:|.|:.|..:|:..:||:    ..|..|...|.:...
Mouse   232 GIIQLSMGMLGMGFMATYLPEAATSAYLAAVALHIILAQMTCILGIMVSFHAGPISFIYNIINYC 296

  Fly   173 FGNLHKVRTGDFTLGLTSIIVLLLLRKLKDVKLDGRIRNLRTQQLVSGSIWVIGTGRNALVVLVT 237
            .. |.|..:....|.:||::.|.:.:.::                ::.:.:.|......|::|..
Mouse   297 IA-LPKANSTSILLFITSVVALRINKCIR----------------ITFNRYPIEFPMELLLILGF 344

  Fly   238 SVLAYSTCEQMESCPFILTGKVKSGLPNVSLPKFETTILDRNGTEIRQNFEQMLSELGPSMLIL- 301
            |               :||.|:.....|                      .:||..:.|...:.
Mouse   345 S---------------LLTSKITMATEN----------------------SKMLMNMIPYSFVFP 372

  Fly   302 --PIIAVLGNV---AISKAFGGAGL----------------SPTRELVALSMSNICGAFCSSMPV 345
              |...:|..|   |:|.:|..:.|                :..::|:|:.:.|:..:|......
Mouse   373 ENPEFGILSRVVLQALSLSFVSSFLLISLGKKIANFHNYRTNSNQDLIAIGLCNLLSSFFKCCVF 437

  Fly   346 TGSFSRSAVNHASGVRTPLGGCYTSVLVLLALGLLAPYFQYIPKAALSAVIISAVIFMIEFEVIK 410
            |||.||:.:...||.|........:.::||.:..:..:|..:|.|.|:.:|:|.|:..:|.....
Mouse   438 TGSLSRTTIQDKSGGRQQFASLVGAGVMLLLMVKMESFFHNLPNAVLAGIILSNVVPYLEAIYNL 502

  Fly   411 P-LWRCSRRELLPGAITFVMSLAVGVEIGLLLGVSTDVAFLVYRAAR-PVLSVSKLQTTN 468
            | |||..:.|.:...:||..::.:|:::|||:.::.....:..|:.| .:|.:.::..||
Mouse   503 PSLWRQDQYECIIWMVTFSSAILLGLDVGLLISLAFTFFVITIRSHRTKILVLGQIPNTN 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	sulP	12..531	CDD:273284	115/513 (22%)
CG6928	NP_648539.1	STAS_SulP_like_sulfate_transporter	471..>540	CDD:132913
Slc26a8	XP_011244686.1	sulP	104..610	CDD:273284	115/513 (22%)
Slc26a8	XP_011244686.1	STAS_SulP_like_sulfate_transporter	<747..806	CDD:132913
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820