DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6928 and sulp-2

DIOPT Version :9

Sequence 1:	NP_648539.1	Gene:	CG6928 / 39367	FlyBaseID:	FBgn0036240	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_508944.1	Gene:	sulp-2 / 180828	WormBaseID:	WBGene00017464	Length:	652	Species:	Caenorhabditis elegans

Alignment Length:	574	Identity:	133/574 - (23%)
Similarity:	253/574 - (44%)	Gaps:	81/574 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LRKWGYRLLPGLKWLHGYTGQDAVADLIAGVTVGLTVLPQGLAYATLAGLEPQYGLYSAFVGGII 67
            :||...|.:|.:.|:..|...:..:|.|||:|:|:..:||.::|:.||||.|.||||::|....:
Worm    37 IRKIILRRVPVIDWIGSYQINNFASDFIAGLTMGVYNVPQAMSYSILAGLPPVYGLYASFFPPFL 101

  Fly    68 YAMLGSCRQVTIGPTALLALMTSR----------HTGFGLGSGPAYAIL--LCLISGVVELGMAV 120
            |::.||.:..:||..::..||..:          .......|..|..|:  ||:::|:::..||:
Worm   102 YSIFGSAKHSSIGVFSITCLMVDKCVKKMLKFRNENPEKFTSVQAIEIVTSLCILTGIIQAVMAI 166

  Fly   121 LKLGALVDLISLPVTVGFTSATAVIIGTSQLKGLLGLRGGSGSD----FINTMRSVFGNLHKVRT 181
            .:....:..:..|.....|.:.......||:..|.|....|.::    .::::..:|.|.||..|
Worm   167 FRCDKPMKFLGAPAISAITFSACFFGVVSQIPKLCGFSVPSRNEHWFSLVHSILDIFENCHKSNT 231

  Fly   182 GDFTLGLTSIIVLLLLRKLKDVKLDGRIRNLRTQQLVSGSIWVIGTGRNALVVLVTSVLAYSTCE 246
            ....:..::::.|:..|    :.::...:|.:..|.:.....:|      .:|:.||...:...|
Worm   232 ATLCISASALVFLIGSR----IFIEPFFKNHKKLQSIPFPKELI------TIVIATSASYFFDFE 286

  Fly   247 QMESCPFILTGKVKSGLPNVSLPKFETTILDRNGTEIRQNFEQMLSELGPSMLILPIIAVLGNVA 311
            .......:.|  |..|.|...:|:.:..         ...|:..||        :.::|....:|
Worm   287 HRFGVKTLHT--VPRGFPYPDVPRIDIW---------PYIFQDALS--------IAVVAYAVTMA 332

  Fly   312 ISKAFGGA---GLSPTRELVALSMSNICGAFCSSMPVTGSFSRSAVNHASGVRTPLGGCYTSVLV 373
            :.:.|...   .:...:||:||...||..:|.|..|.:.||||:.||..||.:|.|.|..::..:
Worm   333 MGQEFATKHRYRIDSNQELLALGFINIGSSFFSVFPTSASFSRTLVNERSGAKTQLSGITSACFM 397

  Fly   374 LLALGLLAPYFQYIPKAALSAVIISAVIFMI-EFEVIKPLWRCSRRELLPGAITFVMSLAVGVEI 437
            .|.:..:.||...:|...|||::|..:..|: :..|:..|||||:.:.....||.|::|:..:..
Worm   398 ALVITTIGPYLASLPSCILSAIVIVVLESMLRKCTVLPGLWRCSKHDFWIWIITAVVTLSSDIAQ 462

  Fly   438 GLLLGVSTDVAFLVYRAARPVLS------------VSKLQTTNGINYILIRPKHSSLYFPAVEW- 489
            |:..|:.|.:..:..::.:|.:.            ::........::.:|| ..:.|.|..||.
Worm   463 GVAAGIFTAIFTIAIQSQQPTIKLLGQIRPNDFRPMNHYSLAKETSFRIIR-FDAPLIFANVEKF 526

  Fly   490 ---VRSGISKALTIHGTA-----------PVVLDCAHVHEFDFTAARGMGSLQK 529
               ||...| |.|...:|           .::|||   |.:.:|.:.|:.::::
Worm   527 LDNVRDSTS-ATTKKRSASCDSQEDIEWSAIILDC---HTWIYTDSMGIAAVKQ 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	sulP	12..531	CDD:273284	130/565 (23%)
CG6928	NP_648539.1	STAS_SulP_like_sulfate_transporter	471..>540	CDD:132913	18/74 (24%)
sulp-2	NP_508944.1	sulP	46..624	CDD:273284	130/565 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2728
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.660