Protein Alignment CG6928 and SLC26A7

DIOPT Version :10

• Sequence 1: NP_648539.1
• Gene: CG6928 / 39367
• FlyBaseID: FBgn0036240
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_599028.1
• Gene: SLC26A7 / 115111
• HGNCID: 14467
• Length: 663
• Species: Homo sapiens
• Alignment Length: 691
• Identity: 153/691 - (22%)
• Similarity: 275/691 - (39%)
• Gaps: 182/691 - (26%)

  Fly     5 KWGYRLLPGLKWLHGYT-GQDAVADLIAGVTVGLTVLPQGLAYATLAGLEPQYGLYSAFVGGIIY 68
            :|..|.||.|.|...|. .::.:.|.::|:.:.:..:.||||:|.|:.:.|.:|||.:....|||
Human    26 QWCRRRLPILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSSVHPVFGLYGSLFPAIIY 90

  Fly    69 AMLGSCRQVTIGPTALLALMT------------------SRHTGFGLGSGPA----YAILLCLIS 111
            |:.|....|..|..||.:|::                  |..:..||.....    .|..:..:.
Human    91 AIFGMGHHVATGTFALTSLISANAVERIVPQNMQNLTTQSNTSVLGLSDFEMQRIHVAAAVSFLG 155

  Fly   112 GVVELGMAVLKLGALVDLISLPVTVGFTSATAVIIGTSQLKGLLGLR-----GGSGSDFINTMRS 171
            ||:::.|.||:||:...:::.||....|:..|..:.|||:|.|||::     |..|  |......
Human   156 GVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYLLGMKMPYISGPLG--FFYIYAY 218

  Fly   172 VFGNLHKVRTGDFTLGLTSIIVLLLLRKLKDVKLDGRIRNLRTQQLVSGSIWVIGTGRNALVVLV 236
            ||.|:..||.....|.|.||:||:|:::|.: :...:|:.:....||              :::.
Human   219 VFENIKSVRLEALLLSLLSIVVLVLVKELNE-QFKRKIKVVLPVDLV--------------LIIA 268

  Fly   237 TSVLAYSTCEQMESCPFI-LTGKVKSGLPNVSLPKFETTILDRNGTEIRQNFEQMLSELGPSMLI 300
            .|...|  |..||:...: :.|.:..|:|:...|..  .||....||          ..|
Human   269 ASFACY--CTNMENTYGLEVVGHIPQGIPSPRAPPM--NILSAVITE----------AFG----- 314

  Fly   301 LPIIAVLGNVA-ISKAFGGA-----GLSPTRELVALSMSNICGAFCSSMPVTGSFSRSAVNHASG 359
               :|::|.|| ::.|.|.|     .:...:|.:|..:|||..:|...:|...:..|:|..:::|
Human   315 ---VALVGYVASLALAQGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAMGRTAGLYSTG 376

  Fly   360 VRTPLGGCYTSVLVLLALGLLAPYFQYIPKAALSAVIISAVI-FMIEFEVIKPLWRCSRRELLPG 423
            .:|.:....:.:.||:.:..:.|...::|...|:::|:..:. .:|:|..:|..|...:.:....
Human   377 AKTQVACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGIW 441

  Fly   424 AITFVMSLAVGVEIGLLLGVSTDVAFLVYRAARPVLSVSKLQTTNGINYILIRPKHSSLYFPAVE 488
            ..|:|.::.....:|||.||...:|.::.|                              ||
Human   442 VSTYVFTICFAANVGLLFGVVCTIAIVIGR------------------------------FP--- 473

  Fly   489 WVRSGISKALTIHGTAPVVLDCAHVHEFDFTAARGMGS---LQKELAKANAPLFLMSADK----T 546
                   :|:|:        ...::.|.:|.....|.|   .|.::...|.||..::|.|    .
Human   474 -------RAMTV--------SIKNMKEMEFKVKTEMDSETLQQVKIISINNPLVFLNAKKFYTDL 523

  Fly   547 IGVILKESTNIDFPTID-------------------------CPDDLEFLLEQTA-----DY--- 578
            :.:|.||:. .:.|..|                         ||::..:|:...:     ||
Human   524 MNMIQKENA-CNQPLDDISKCEQNTLLNSLSNGNCNEEASQSCPNEKCYLILDCSGFTFFDYSGV 587

  Fly   579 ----------------VLHLQISAPLVESRLVHG--DSGEP 601
                            ||....:|.|:::...:|  ||.:|
Human   588 SMLVEVYMDCKGRSVDVLLAHCTASLIKAMTYYGNLDSEKP 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	SUL1	19..540	CDD:440424	127/559 (23%)
SLC26A7	NP_599028.1	PRK11660	33..637	CDD:481320	150/684 (22%)