Protein Alignment CG6928 and Slc26a3

DIOPT Version :10

• Sequence 1: NP_648539.1
• Gene: CG6928 / 39367
• FlyBaseID: FBgn0036240
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_446207.1
• Gene: Slc26a3 / 114629
• RGDID: 620623
• Length: 757
• Species: Rattus norvegicus
• Alignment Length: 666
• Identity: 161/666 - (24%)
• Similarity: 294/666 - (44%)
• Gaps: 117/666 - (17%)

  Fly     4 RKWGYRLLPGLKWLHGYTGQD-AVADLIAGVTVGLTVLPQGLAYATLAGLEPQYGLYSAFVGGII 67
            :|....|.|...||..|..:: .::|:::|::.||..:.||||:|.|..:.|.||||:||...|.
  Rat    51 KKIALSLFPIASWLPAYKIKEWLLSDIVSGISTGLVAVLQGLAFALLVNIPPAYGLYAAFFPVIT 115

  Fly    68 YAMLGSCRQVTIGPTALLALMTS---RHTGFGLGSGPA-----------------YAILLCLISG 112
            |..||:.|.:::||..:|::|..   .....|..:.||                 .|..:.::||
  Rat   116 YFFLGTSRHISVGPFPVLSMMVGVVVTRVASGSDTSPALSSSSAENDSMIEEKVMVAASVTVLSG 180

  Fly   113 VVELGMAVLKLGALVDLISLPVTVGFTSATAVIIGTSQLKGLLGLRGGSGSD---FINTMRSVFG 174
            :::|.:.||::|.:|..:|..:..|||:|.|:.:..||||.:|.|...:.||   ....:.|||.
  Rat   181 IIQLLLGVLQIGFVVIYLSESLISGFTTAAAIHVLVSQLKFMLQLTVPAHSDPFSIFKVLESVFS 245

  Fly   175 NLHKVRTGDFTLGLTSIIVLLLLRKLKDVKLDGRIRNLRTQQLVSGSIWVIGTGRNALVVLVTSV 239
            .:.|....|.   :||:|:|:::..:|::.     :..|::..|...|.:|      :.|:.|.:
  Rat   246 QIQKTNIADL---VTSVIILVVVFVVKEIN-----QRYRSKLPVPIPIELI------MTVIATGI 296

  Fly   240 LAYSTCEQMESCPFILTGKVKSGL-----PNVSLPKFETTILDRNGTEIRQNFEQMLSELGPSML 299
             :|. |...:.....:.|.:..|.     |:|.:  |:.||.|..|
  Rat   297 -SYG-CNFEQRFGVAVVGNMSLGFQPPITPSVEV--FQDTIGDCFG------------------- 338

  Fly   300 ILPIIAVLGNVAISKAFGGAG---------LSPTRELVALSMSNI-CGAFCSSMPVTGSFSRSAV 354
                ||::|   .:.||..|.         :...:||:||.:||| .||| .....:.:.|||.|
  Rat   339 ----IAIVG---FAVAFSVASVYSLKYDYPIDGNQELIALGVSNIFTGAF-KGFAGSTALSRSGV 395

  Fly   355 NHASGVRTPLGGCYTSVLVLLALGLLAPYFQYIPKAALSAVIISAVIFMI-EFEVIKPLWRCSRR 418
            ..::|.:|.:.|..::|:||:.:..:....|.:.|:.|:|:.:..:..|: :|..|..||:..:.
  Rat   396 QESTGGKTQVAGLLSAVIVLIVIVAIGFLLQPLQKSVLAALALGNLKGMLMQFAEIGRLWKKDKY 460

  Fly   419 ELLPGAITFVMSLAVGVEIGLLLGVSTDVAFLVYRAARPVLSVSKLQTTNGINYILIRPKHSSLY 483
            :.|...:||:.::.:|:.:||...|:..:..:|:|...|  ..|.|......|....:..::.:|
  Rat   461 DCLIWIMTFIFAIVLGLGLGLAASVAFQLLTIVFRTQFP--KCSTLANVGRSNIYKNKKNYADVY 523

  Fly   484 FP----------AVEWVRSGISKALTIH--GTAPVVLDCAHVHEFDFTAARGMGSLQKE-LAKAN 535
            .|          .:.:...|..|...|.  |..|:     .:......|.:.:..|||: |.:..
  Rat   524 EPEGVKIFRCPSPIYFANIGFFKQKLIDAVGFNPL-----RILRKRNKALKKIRKLQKQGLIQVT 583

  Fly   536 APLFLMSADKTIGVILKES----TNIDFPTIDCP---DDLEFLLEQTADYVLHLQISAPLVESRL 593
            ...|:.::|.     .|:|    .|.....:|.|   .||.|.::..||..|::.|....:.|.:
  Rat   584 PKGFICTSDG-----FKDSDEELDNNQIEELDQPINTTDLPFEIDWNADLPLNITIPKISLHSLI 643

  Fly   594 VHGDSGEPTELSKLNG 609
            :...:....::|.:.|
  Rat   644 LDFSAVSFLDISSMRG 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	SUL1	19..540	CDD:440424	139/573 (24%)
Slc26a3	NP_446207.1	Sulfate_transp	73..468	CDD:459995	114/439 (26%)
		STAS_SulP_like_sulfate_transporter	519..705	CDD:132913	29/151 (19%)
		PDZ-binding. /evidence=ECO:0000250|UniProtKB:P40879	754..757