DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6928 and slc26a9

DIOPT Version :9

Sequence 1:	NP_648539.1	Gene:	CG6928 / 39367	FlyBaseID:	FBgn0036240	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	XP_031751455.1	Gene:	slc26a9 / 100124761	XenbaseID:	XB-GENE-996559	Length:	839	Species:	Xenopus tropicalis

Alignment Length:	620	Identity:	131/620 - (21%)
Similarity:	260/620 - (41%)	Gaps:	112/620 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LRKWGYRLLPGLKWLHGYTGQ-DAVADLIAGVTVGLTVLPQGLAYATLAGLEPQYGLYSAFVGGI 66
            ::.:.:||.|.|.||..|..: :.:.|.:.|::.|...:|||:|:|.||.|.|..||||:|...:
Frog    91 IKNFIFRLFPILSWLPKYNIKGNLLNDALGGISAGTIQIPQGMAFALLANLPPVNGLYSSFFPLV 155

  Fly    67 IYAMLGSCRQVTIGPTALLALM-------------------TSRHTGFGL----GSGPAYAILLC 108
            :|..:|...|:..|..|:::::                   ||..|...:    |.....:..|.
Frog   156 VYFFMGGIPQMVPGTFAVISIIVGNVCLKLAPESEFVTINGTSNVTFIDIEAMNGKRMHISATLA 220

  Fly   109 LISGVVELGMAVLKLGALVDLISLPVTVGFTSATAVIIGTSQLKGLLGLRGGSGSD---FINTMR 170
            .::.::::.::.::.|.:...:|.....||.:|..:.|..|.||.:.|:.....|.   .|.|..
Frog   221 CLTAIIQIALSFVQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGVSIPPYSGVLAIIYTFI 285

  Fly   171 SVFGNLHKVRTGDFTLGLTSIIVLLLLRKLKDVKLDGRIRNLRTQQLVSGSIWVIGTGRNALVVL 235
            .:...|.|.........|.|.::|:::::| ::|...:||.....:::             :|::
Frog   286 DICKELPKTNVASLIFALISTVLLIIVKEL-NMKFMHKIRFPIPMEII-------------IVIV 336

  Fly   236 VTSVLAYSTCEQMESCPFILTGKVKSGLPNVSLPKFETTILDRNGTEIRQNFEQMLSELGPSMLI 300
            .|:|  ..:.:..|.....:.|.:..|.|:.::|         |.|:    :::|:.    :...
Frog   337 ATAV--SGSFKLPERYHMNVVGHIPLGFPSPTVP---------NVTQ----WDEMVG----TAFS 382

  Fly   301 LPIIAVLGNVAISKAFG---GAGLSPTRELVALSMSNICGAF------CSSMPVTGSFSRSAVNH 356
            |.|:..:.|:|:.:..|   |..:...:|::||...|..|:|      |.::.||     .||:.
Frog   383 LAIVGYVINLAMGRTLGAKHGFDVDANQEMLALGSGNFFGSFFFIHVICCALSVT-----LAVDG 442

  Fly   357 ASGVRTPLGGCYTSVLVLLALGLLAPYFQYIPKAALSAVIISAVIFMIEFEVIKP---LWRCSRR 418
            |.| ::.:...:..:.|::.:..|..|...:||:.|.|:|  ||......:.:..   ||:.|:.
Frog   443 AGG-KSQIASFFVMMSVMVTILALGTYLNPLPKSVLGALI--AVNLKNSLKQLSDPFYLWKKSKL 504

  Fly   419 ELLPGAITFVMSLAVGVEIGLLLGVSTDVAFLVYRA-----------------ARPVLSVSKLQT 466
            :.|...::|..:..:|:..||.:||:..:..:::..                 ..|.: .||:|.
Frog   505 DCLVWLVSFFSTFILGLPYGLAVGVAFSILVVIFNTQFRNGSSLNQVTATDIYVNPKV-YSKVQP 568

  Fly   467 TNGINYILIRPKHSSLYFPAVEWVRSGISKALTIHGTAPVVLDCAHVHEFDFTAARGMGSLQKEL 531
            .:||..:..   .|.|||...|..|..:.|..   |..|   ...::.:..:...:.....:||.
Frog   569 IDGIKIVTY---CSPLYFANSEIFRQKVIKKT---GLDP---GKVYLSKKKYLKQQEQELKKKEQ 624

  Fly   532 AKANAPLFLMSADKTIGVILKESTNIDFPTIDCPD 566
            .|....||:  .:||:.:   :....||..:...|
Frog   625 KKKRGSLFM--KNKTLSL---QELQEDFDGVSPTD 654

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	sulP	12..531	CDD:273284	120/574 (21%)
CG6928	NP_648539.1	STAS_SulP_like_sulfate_transporter	471..>540	CDD:132913	13/68 (19%)
slc26a9	XP_031751455.1	sulP	100..604	CDD:273284	119/554 (21%)
slc26a9	XP_031751455.1	STAS_SulP_like_sulfate_transporter	<708..777	CDD:132913
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910