DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6928 and slc26a6

DIOPT Version :9

Sequence 1:	NP_648539.1	Gene:	CG6928 / 39367	FlyBaseID:	FBgn0036240	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	XP_001344243.4	Gene:	slc26a6 / 100005108	ZFINID:	ZDB-GENE-081105-83	Length:	747	Species:	Danio rerio

Alignment Length:	544	Identity:	132/544 - (24%)
Similarity:	250/544 - (45%)	Gaps:	97/544 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LPGLKWLHGYT-GQDAVADLIAGVTVGLTVLPQGLAYATLAGLEPQYGLYSAFVGGIIYAMLGSC 74
            :|.|.||..|. .::|:.|||:|::||:..||||:|||.||.:.|.:||||:|...:||.:.|:.
Zfish    62 IPLLAWLPKYPFRENAIGDLISGISVGIMHLPQGMAYALLAAVPPVFGLYSSFYPILIYFIFGTS 126

  Fly    75 RQVTIGPTALLALM----------TSRHTGFGLGSGPAY-------------AILLCLISGVVEL 116
            :.:::|..|::::|          .|..|..|..:...|             |..:..:||:.:|
Zfish   127 KHISVGTYAVMSVMIGSVTERLAPDSDFTFPGNETNSTYIDFSSRDAERVKIAATVTFLSGIFQL 191

  Fly   117 GMAVLKLGALVDLISLPVTVGFTSATAVIIGTSQLKGLLGL---RGGSGSDFINTMRSVFGNLHK 178
            .:.|::.|.:|..:|.|:...:|:|.|:.:..||||...|:   |.......|.|:..:...|.|
Zfish   192 LLGVVRFGFVVTYLSEPLVRSYTTAAAIHVIVSQLKYSFGINPHRYSGPLSLIYTVIEICALLGK 256

  Fly   179 VRTGDFTLGLTSIIVLLLLRKLKDVKLDGRIRNLRTQQLVSGSIWVIGTGRNALVVLVTSVLAY- 242
            ...|...:.:.:|:.|::.::|              ..|.:..| .|......:.:::.:|:::
Zfish   257 TNIGTLVVSIVTIVGLIIAKEL--------------SALAAKKI-PIPIPVELITIIIATVVSWY 306

  Fly   243 ---STCEQMESCPFILTGKVKSGLPNVSLPKFETTILDRNGTEIRQNFEQMLSELGPSMLILPII 304
               .|..::|     :.|::.|||.....||                    :|:||..:.....:
Zfish   307 MDLKTIYKVE-----VVGEIPSGLQAPVAPK--------------------VSQLGSMVGDAFAL 346

  Fly   305 AVLG-NVAIS--KAFG---GAGLSPTRELVALSMSNICGAFCSSMPVTGSFSRSAVNHASGVRTP 363
            ||:| .:|||  :.|.   ...:...:||:||.:||..|...|...::.|.|||.|..::|.::.
Zfish   347 AVVGYGIAISLGRIFALKYAYKVDSNQELIALGLSNSIGGLFSCFAISCSMSRSMVQVSTGGKSQ 411

  Fly   364 LGGCYTSVLVLLALGLLAPYFQYIPKAALSAVI-ISAVIFMIEFEVIKPLWRCSRRELLPGAITF 427
            :.|..:::::|:.|..:...|:.:|||.|:|:| ::....|.:|..|..|||.::.:::...:|.
Zfish   412 VAGAISALVILVILLKIGELFEELPKAVLAAIIYVNLQGMMKQFGDICSLWRTNKVDMVVWVMTM 476

  Fly   428 VMSLAVGVEIGLLLGVSTDVAFLVYRAARPVLS-------------VSKLQTTNGINYILIRPKH 479
            ::::....::||...::..:..:|:|...|..|             |........|..|.|....
Zfish   477 ILTILFNPDMGLAASIAFSILTVVFRTQLPKYSILGQIPGTDIYKPVEDYNQVKEIPGITIFRSS 541

  Fly   480 SSLYFPAVE------WVRSGISKA 497
            ::|||...|      :.::|:..|
Zfish   542 ATLYFANAEMYIDALYEKTGVDVA 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6928	NP_648539.1	sulP	12..531	CDD:273284	132/543 (24%)
CG6928	NP_648539.1	STAS_SulP_like_sulfate_transporter	471..>540	CDD:132913	8/33 (24%)
slc26a6	XP_001344243.4	sulP	63..729	CDD:273284	132/543 (24%)
slc26a6	XP_001344243.4	STAS_SulP_like_sulfate_transporter	<655..725	CDD:132913
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.710