DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pop2 and POP2

DIOPT Version :9

Sequence 1:	NP_001287041.1	Gene:	Pop2 / 39366	FlyBaseID:	FBgn0036239	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_014450.3	Gene:	POP2 / 855788	SGDID:	S000005335	Length:	433	Species:	Saccharomyces cerevisiae

Alignment Length:	272	Identity:	102/272 - (37%)
Similarity:	160/272 - (58%)	Gaps:	21/272 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PHAHIPSNEECGIRDVWKQNLEEEFRTIRKVVQKYHYVAMDTEFPGVVARPVGEFRSTADYHYQL 77
            |...:|......:|||||.||..||..||::|.:|::|::.|||.|.:|||:|.|||..|||||.
Yeast   148 PPIFLPPPNYLFVRDVWKSNLYSEFAVIRQLVSQYNHVSISTEFVGTLARPIGTFRSKVDYHYQT 212

  Fly    78 LRCNVDLLRIIQLGLTFMDDDGKTPP-GYSTWQFNFKFNLSEDMYAQDSIDLLQNSGIQFKKHEE 141
            :|.|||.|..|||||:..|.:|..|. |.|||||||:|:..:::.:.:|::||:.|||.|:|||.
Yeast   213 MRANVDFLNPIQLGLSLSDANGNKPDNGPSTWQFNFEFDPKKEIMSTESLELLRKSGINFEKHEN 277

  Fly   142 DGIDPIDFAELLMSSGIVLVENIKWLCFHSGYDFGYLLKLLTDQNLPPDESEFFDLLHIYFPNIF 206
            .|||..:|::|||.||:::.:::.|:.:|:.||.|:|:.:|.:.::|.::.:|...:|.|.||.:
Yeast   278 LGIDVFEFSQLLMDSGLMMDDSVTWITYHAAYDLGFLINILMNDSMPNNKEDFEWWVHQYMPNFY 342

  Fly   207 DIKYLMKSCKNLKG---------------GLQEVADQLELRRVGPQHQAGSDALLTGMAF----- 251
            |:..:.|..:..|.               .|..:||:|.|.|.......|..:||..::|
Yeast   343 DLNLVYKIIQEFKNPQLQQSSQQQQQQQYSLTTLADELGLPRFSIFTTTGGQSLLMLLSFCQLSK 407

  Fly   252 FKMREVQHTNDF 263
            ..|.:..:..||
Yeast   408 LSMHKFPNGTDF 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pop2	NP_001287041.1	CAF1	25..257	CDD:304961	98/252 (39%)
POP2	NP_014450.3	POP2	141..433	CDD:227553	102/272 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346439
Domainoid	1	1.000	132	1.000	Domainoid score	I1117
eggNOG	1	0.900	-	-		E1_COG5228
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	202	1.000	Inparanoid score	I849
Isobase	1	0.950	-	0	Normalized mean entropy	S870
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001271
OrthoInspector	1	1.000	-	-		oto99287
orthoMCL	1	0.900	-	-		OOG6_101138
Panther	1	1.100	-	-	LDO	PTHR10797
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R161
SonicParanoid	1	1.000	-	-		X785
TreeFam	1	0.960	-	-
	14	13.730