DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pop2 and cnot7

DIOPT Version :9

Sequence 1:	NP_001287041.1	Gene:	Pop2 / 39366	FlyBaseID:	FBgn0036239	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	XP_021336741.1	Gene:	cnot7 / 768119	ZFINID:	ZDB-GENE-061013-29	Length:	295	Species:	Danio rerio

Alignment Length:	326	Identity:	187/326 - (57%)
Similarity:	231/326 - (70%)	Gaps:	52/326 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PHAHIPSNEECGIRDVWKQNLEEEFRTIRKVVQKYHYVAMDTEFPGVVARPVGEFRSTADYHYQL 77
            |.|.:..::.  |.:||..|||||.:.||:|.:|::|:|||||||||||||:|||||.|||.|||
Zfish     2 PAATVDHSQR--ICEVWACNLEEEMKRIRQVTRKFNYIAMDTEFPGVVARPIGEFRSNADYQYQL 64

  Fly    78 LRCNVDLLRIIQLGLTFMDDDGKTPPGYSTWQFNFKFNLSEDMYAQDSIDLLQNSGIQFKKHEED 142
            ||||||||:|||||||||::.|:.|||.|||||||||||:|||||||||:||.:||||||||||:
Zfish    65 LRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTSSGIQFKKHEEE 129

  Fly   143 GIDPIDFAELLMSSGIVLVENIKWLCFH---------SGYDFGYLLKLLTDQNLPPDESEFFDLL 198
            ||:.:.||||||:||:||.|.:|||.||         ||||||||:|:|::..||.:|.:||::|
Zfish   130 GIETMYFAELLMTSGVVLCEGVKWLSFHRHILVFLLNSGYDFGYLIKILSNSKLPDEEVDFFEIL 194

  Fly   199 HIYFPNIFDIKYLMKSCKNLKGGLQEVADQLELRRVGPQHQAGSDALLTGMAFFKMREVQHTNDF 263
            .::||.|:|:||||||||||||||||||:||||.|:|||||||||:||||||||||||:
Zfish   195 RLFFPIIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFKMREM------ 253

  Fly   264 HITPVAHDVLFRYLLEHTMNLKPTISCIHLLSRPAYNGGPAPDESAIISSG-----NGTGNTNST 323
                        :..:|..:.|   .|.||..               :.||     |||||....
Zfish   254 ------------FFEDHIDDAK---YCGHLYG---------------LGSGSSYVQNGTGNAYEE 288

  Fly   324 E 324
            |
Zfish   289 E 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pop2	NP_001287041.1	CAF1	25..257	CDD:304961	171/240 (71%)
cnot7	XP_021336741.1	CAF1	1..288	CDD:329090	186/323 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595755
Domainoid	1	1.000	203	1.000	Domainoid score	I2918
eggNOG	1	0.900	-	-		E1_COG5228
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49011
Inparanoid	1	1.050	384	1.000	Inparanoid score	I1996
OMA	1	1.010	-	-		QHG54002
OrthoDB	1	1.010	-	-		D365788at33208
OrthoFinder	1	1.000	-	-		FOG0001271
OrthoInspector	1	1.000	-	-		otm26565
orthoMCL	1	0.900	-	-		OOG6_101138
Panther	1	1.100	-	-	LDO	PTHR10797
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R161
SonicParanoid	1	1.000	-	-		X785
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800