DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pop2 and Cnot7

DIOPT Version :9

Sequence 1:	NP_001287041.1	Gene:	Pop2 / 39366	FlyBaseID:	FBgn0036239	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	XP_017455614.1	Gene:	Cnot7 / 306492	RGDID:	1305313	Length:	298	Species:	Rattus norvegicus

Alignment Length:	330	Identity:	190/330 - (57%)
Similarity:	231/330 - (70%)	Gaps:	56/330 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PHAHIPSNEECGIRDVWKQNLEEEFRTIRKVVQKYHYVAMDTEFPGVVARPVGEFRSTADYHYQL 77
            |.|.:..::.  |.:||..||:||.:.||:|::||:|||||||||||||||:|||||.|||.|||
  Rat     2 PAATVDHSQR--ICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADYQYQL 64

  Fly    78 LRCNVDLLRIIQLGLTFMDDDGKTPPGYSTWQFNFKFNLS-------------EDMYAQDSIDLL 129
            ||||||||:|||||||||::.|:.|||.|||||||||||:             |||||||||:||
  Rat    65 LRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTSGTALGPGNPYFWEDMYAQDSIELL 129

  Fly   130 QNSGIQFKKHEEDGIDPIDFAELLMSSGIVLVENIKWLCFHSGYDFGYLLKLLTDQNLPPDESEF 194
            ..||||||||||:||:...||||||:||:||.|.:|||.||||||||||:|:||:.|||.:|.:|
  Rat   130 TTSGIQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELDF 194

  Fly   195 FDLLHIYFPNIFDIKYLMKSCKNLKGGLQEVADQLELRRVGPQHQAGSDALLTGMAFFKMREVQH 259
            |::|.::||.|:|:||||||||||||||||||:||||.|:|||||||||:||||||||||||:
  Rat   195 FEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFKMREM-- 257

  Fly   260 TNDFHITPVAHDVLFRYLLEHTMNLKPTISCIHLLSRPAYNGGPAPDESAIISSG-----NGTGN 319
                            :..:|..:.|   .|.||..               :.||     |||||
  Rat   258 ----------------FFEDHIDDAK---YCGHLYG---------------LGSGSSYVQNGTGN 288

  Fly   320 TNSTE 324
            ....|
  Rat   289 AYEEE 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pop2	NP_001287041.1	CAF1	25..257	CDD:304961	174/244 (71%)
Cnot7	XP_017455614.1	CAF1	1..292	CDD:420020	189/327 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353616
Domainoid	1	1.000	195	1.000	Domainoid score	I3051
eggNOG	1	0.900	-	-		E1_COG5228
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49011
Inparanoid	1	1.050	376	1.000	Inparanoid score	I2020
OMA	1	1.010	-	-		QHG54002
OrthoDB	1	1.010	-	-		D365788at33208
OrthoFinder	1	1.000	-	-		FOG0001271
OrthoInspector	1	1.000	-	-		otm44958
orthoMCL	1	0.900	-	-		OOG6_101138
Panther	1	1.100	-	-	LDO	PTHR10797
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X785
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770