DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pop2 and ccf-1

DIOPT Version :9

Sequence 1:	NP_001287041.1	Gene:	Pop2 / 39366	FlyBaseID:	FBgn0036239	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_499553.1	Gene:	ccf-1 / 176625	WormBaseID:	WBGene00000369	Length:	310	Species:	Caenorhabditis elegans

Alignment Length:	301	Identity:	134/301 - (44%)
Similarity:	188/301 - (62%)	Gaps:	21/301 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SGAPHAHIPSNEECGIRDVWKQNLEEEFRTIRKVVQKYHYVAMDTEFPGVVARPVGEFRSTADYH 74
            ||||        |..|.:|:..|:||||..||..|:.|.|||||||||||||.|:|.|||..|::
Worm    16 SGAP--------EVKIHNVYMSNVEEEFARIRGFVEDYPYVAMDTEFPGVVATPLGTFRSKEDFN 72

  Fly    75 YQLLRCNVDLLRIIQLGLTFMDDDGKTPPGYSTWQFNFKFNLSEDMYAQDSIDLLQNSGIQFKKH 139
            ||.:.|||::|::||:|...::|.|:.||....|||||.|:.:|||::.:|:::|:.:||.|...
Worm    73 YQQVFCNVNMLKLIQVGFAMVNDKGELPPTGDVWQFNFNFSFAEDMFSHESVEMLRQAGIDFTLL 137

  Fly   140 EEDGIDPIDFAELLMSSGIVLVENIKWLCFHSGYDFGYLLKLLTDQNLPPDESEFFDLLHIYFPN 204
            :.:||....|.|||.:||::....|.||.|.||||||||||.:|..:||.:||.||......||.
Worm   138 QNNGIPTAVFGELLTTSGLITDPRITWLTFSSGYDFGYLLKSITLGDLPKEESTFFMCHKTLFPT 202

  Fly   205 IFDIKYLMK--SCKN--LKGGLQEVADQLELRRVGPQHQAGSDALLTGMAFFKMREVQHTNDFH- 264
            .||||.|::  :|.:  ||||||||||||:::|.|.:||||||||||...|||:::....::::
Worm   203 SFDIKILLRTPNCASAKLKGGLQEVADQLDVKRQGVRHQAGSDALLTAATFFKIKKQFFGDNWNQ 267

  Fly   265 ITPVAHDVLFRYLLEHTMNLKPTISCIHLLSRPAYNGGPAP 305
            |.|:        :..|...|..::|..|.....:..|...|
Worm   268 IAPL--------ICGHMFGLGSSLSLFHSSGSTSRLGDETP 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pop2	NP_001287041.1	CAF1	25..257	CDD:304961	121/235 (51%)
ccf-1	NP_499553.1	CAF1	23..292	CDD:304961	127/276 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167121
Domainoid	1	1.000	131	1.000	Domainoid score	I3213
eggNOG	1	0.900	-	-		E1_COG5228
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49011
Inparanoid	1	1.050	245	1.000	Inparanoid score	I2053
Isobase	1	0.950	-	0	Normalized mean entropy	S870
OMA	1	1.010	-	-		QHG54002
OrthoDB	1	1.010	-	-		D365788at33208
OrthoFinder	1	1.000	-	-		FOG0001271
OrthoInspector	1	1.000	-	-		oto20391
orthoMCL	1	0.900	-	-		OOG6_101138
Panther	1	1.100	-	-	LDO	PTHR10797
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R161
SonicParanoid	1	1.000	-	-		X785
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790