Protein Alignment CG6938 and ano10a

DIOPT Version :10

• Sequence 1: NP_001261733.1
• Gene: CG6938 / 39362
• FlyBaseID: FBgn0036235
• Length: 1245
• Species: Drosophila melanogaster
• Sequence 2: XP_073781283.1
• Gene: ano10a / 566425
• ZFINID: ZDB-GENE-050913-43
• Length: 660
• Species: Danio rerio
• Alignment Length: 671
• Identity: 163/671 - (24%)
• Similarity: 258/671 - (38%)
• Gaps: 204/671 - (30%)

  Fly   519 RSGIRRLMNDGTYLGCFPLHEGRYDRPHSSGISLDRRVLYQTWAHPSQWYKK-----QPLCLVRK 578
            :|.:|||.:.|..:..|||| .:.|.         :|:.:       .||||     |||..:|.
Zfish   155 KSIVRRLQSKGVLVQYFPLH-NKEDL---------KRLSF-------SWYKKIKLSFQPLDDIRS 202

  Fly   579 YFGDKIALYFCWLGFYTEMLVYPAVVGTLCFIYGLATLESEDNTPSKEICNEYGTGNITLCPLCD 643
            |||:.:.|||.:|.::|..|:..|::|
Zfish   203 YFGEGLGLYFGFLEYFTFALIPMALIG-------------------------------------- 229

  Fly   644 KACSYQRLSESCLFSRLTYLF---DNPSTVFFAIFMSFWATTFLELWKRKQSVLVWEW-DLHNVD 704
              ..|             |||   |....|.||:|...|:|.|||:|||..:.|.:.| .|....
Zfish   230 --IPY-------------YLFDWEDYDKYVLFAVFNLVWSTVFLEVWKRCSATLAYSWGTLGRKK 279

  Fly   705 MDEENRPEFETNATTFRMNPVTREKEPYMSTWNRSIRFVITGSAVLFMISVVLSAVLGTILYRIT 769
            ..||.|..|.   ....:||||..:||...:..|.:|        ::::||....:   .||...
Zfish   280 AFEEPRAGFH---GPLGLNPVTGREEPIYPSSKRHLR--------IYLVSVPFVLL---CLYLSF 330

  Fly   770 LVSVIYGGGGFFV----KEHAKLFTSV---TAALINLVVIMILTRIYHRMAIKLTNLENPRTHTE 827
            .|.::|....|:.    .|:....|||   ..::|..|||.|:..:|...|..||:.||.|..:.
Zfish   331 YVMMVYFDMEFWAISIYHENPNFATSVLLFVPSIIYAVVIEIMNLLYRYAAEFLTDWENHRLESS 395

  Fly   828 YEDSYTFKIFFFEFMNFYSSLIYIAFFKGRFFDYPGDDQARKSEFFRLKNDICDPAGCLSELCIQ 892
            :::....|:..|.|:|.::||.||||.              ..:...|:.              .
Zfish   396 FQNHLVLKVLVFNFVNCFASLFYIAFV--------------MQDMVLLRQ--------------S 432

  Fly   893 LAIIMVGKQCWNNFMEYLFPKFWNWWRQRKHKQATK------DESHLHMAWEQDYHMQDPGRLAL 951
            ||.:::..|..|..||...|   .|.::|::|:..|      .:..|.:..:.....:....|..
Zfish   433 LATLLITSQILNQVMEAFLP---YWLQRRRNKRVYKRMRRLMGDKELPLLEQIQLETEMNTYLGT 494

  Fly   952 FDEYLEMILQYGFVTLFVAAFPLAPLFALLNNVAEIRLDAYKMVTQARRPLAERVEDIGAWYGIL 1016
            ||:|||..|.:|:|:||...:|||.:..:|||:.|:..||:||....:||.:|...:||.|....
Zfish   495 FDDYLEQFLLFGYVSLFSCVYPLAAVLVVLNNITEVYSDAFKMCHVFKRPFSEPAANIGVWQLAF 559

  Fly  1017 RIITYTAVVSNAFVIAYTSDFIPRMVYKFVYSETHTLAGYIEHSLSIFNTSDYKEEWGASVSEKD 1081
            ..::..|||:|..:||.:    |::...|..|:
Zfish   560 ETMSIIAVVTNCALIALS----PQVKAYFPESD-------------------------------- 588

  Fly  1082 PDTCQYRGYRNGPKDYEPYGLSPHYWHVFAARLAFVVVFEHVVFVITGIMQFIIPDVPSEVKTQM 1146
                                         |..:..||..|||:.....|:.|:|||||..::.::
Zfish   589 -----------------------------AQLILTVVAIEHVLLAFKFILAFVIPDVPKHIQVKL 624

  Fly  1147 QREQLLAKEAKYQHGIKRAQG 1167
            .:....:.||..:.  :||.|
Zfish   625 SKLDFESLEALKKR--RRALG 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6938	NP_001261733.1	Anoct_dimer	340..573	CDD:465044	16/58 (28%)
		Anoctamin	576..1149	CDD:461349	140/589 (24%)
ano10a	XP_073781283.1	None