Protein Alignment CG6938 and anoh-1

DIOPT Version :10

• Sequence 1: NP_001261733.1
• Gene: CG6938 / 39362
• FlyBaseID: FBgn0036235
• Length: 1245
• Species: Drosophila melanogaster
• Sequence 2: NP_001255190.1
• Gene: anoh-1 / 176739
• WormBaseID: WBGene00010138
• Length: 840
• Species: Caenorhabditis elegans
• Alignment Length: 926
• Identity: 237/926 - (25%)
• Similarity: 380/926 - (41%)
• Gaps: 222/926 - (23%)

  Fly   345 RRKVDMVLAWEEEDLGVMTEAEAKRRDNRRSFMENLI-KEGLEVELEDKSQSFNEKTFFLKIHLP 408
            |..:|.||        |...||::.:...|.|.|..: ||||.:..:...|     |.|..|..|
 Worm    34 RISIDFVL--------VHNAAESRSKGKYREFFEKAVQKEGLIIRHQQSGQ-----THFTLISTP 85

  Fly   409 WRLETRLAEVMNLKLPVKRFITISVKPSWDEENVVLRNMQYWKDVWQRLTKKIQLDQTLLEGETT 473
            :...||.||:..:..|:|   ...|||......:.|..:....|..:.:....|.....|
 Worm    86 FHRLTREAEMSQMCFPLK---DCQVKPGLPSCCIPLSQIFVTDDTVRFINAPFQRKHGSL----- 142

  Fly   474 FKAATANGNPEEQFIVKDRATAFTSAQRSLMVMQVLIR-----------------TPFDESD--- 518
                ..|.:.|:.|        |||:||..:..|:|.:                 .|.|.|.
 Worm   143 ----FLNYHDEKSF--------FTSSQRGYLTYQILTKIDISKDLKGERLGESQDEPTDPSTSSI 195

  Fly   519 -------RSGIRRLMNDGTYLGCFPLHEGRYDRPH---------------SSGISLD-RRVLYQT 560
                   |.|:..|:....|...|.||....:.|:               .|.|.|| ||.|...
 Worm   196 TSDEQLRRKGLSWLLMSDVYEEAFVLHAPSKEEPYFKAMQNGSVKAYNEFISEIELDPRRSLSLN 260

  Fly   561 WAHPSQWYKKQPLCLVRKYFGDKIALYFCWLGFYTEMLVYPAVV-GTLCFIYGLATLESEDNTPS 624
            |   .:|||.|||..:|.|||::||.||.|.|.:..:| :|||: |.:.||||.  ::|..:.|.
 Worm   261 W---ERWYKFQPLNKIRDYFGEQIAYYFAWQGTFLTLL-WPAVIFGLVVFIYGF--IDSISSAPL 319

  Fly   625 K----EICNEYG-TGNITLCPLCDKACSYQRLSESCLFSRLTY----LFDNPSTVFFAIFMSFWA 680
            .    ::.|..| |.|:        ||. .|...:..||.:|.    .||.....|||:|||.|.
 Worm   320 DWNHCKVVNFIGQTENV--------ACG-MRNGVTLFFSMVTQWFMSSFDTKMNAFFAVFMSIWG 375

  Fly   681 TTFLELWKRKQSVLVWEW---DLHNVDMDEENRPEFETNATTFRMNPVTREKEPYMSTWNRSIRF 742
            :.|:::|||..|||.::|   |.|.::.|   ||||  ..:..:.:|:|.|.........|.|:.
 Worm   376 SVFVQIWKRNNSVLSYQWNSDDFHAIEPD---RPEF--RGSKVKEDPITGEDIWISPALARYIKM 435

  Fly   743 VITGSAVLF-MISVVLSAVLGTILYRITLVSVIYGGGGFF--VKE---HAKLFTSVTAALINLVV 801
            :.:...|.| |:.||:|.:|.|:|    .:.::|.    |  .||   |..|..:...:::|.:.
 Worm   436 LASFVFVSFSMLVVVISLMLVTLL----KIWMVYN----FQCTKEYTFHCWLSAAFLPSILNTLS 492

  Fly   802 IMILTRIYHRMAIKLTNLENPRTHTEYEDSYTFKIFFFEFMNFYSSLIYIAFFKGRFFDYPGDDQ 866
            .|.|..||..:..:|.:.||.||.:|:.:|...|||.|:.:|.|:||.|:||.:      |....
 Worm   493 AMGLGAIYSNLVSRLNSWENHRTESEHNNSLIVKIFAFQMVNTYTSLFYVAFIR------PESHG 551

  Fly   867 ARKSEFFRLK---NDICDPAGCLSELCIQLAIIMVGKQCWNNFMEYLFPKFWNWWRQRKHKQATK 928
            .:.:..|.|.   .|.|....|.|.|.:||....:.|.....|.:.:.|.|...:|.|.:...|:
 Worm   552 LQPNGLFGLGTEFKDTCLDDTCSSLLALQLLTHTLIKPFPKFFKDVVLPYFVKLFRLRMYTSRTE 616

  Fly   929 --------DESHLHMAWEQDYHMQDPGRLALFDEYLEMILQYGFVTLFVAAFPLAPLFALLNNVA 985
                    |::::.:   :::.....|...|: |..|.|:.:|...:|.:.||||||.||:....
 Worm   617 ARVEIEDDDQANVLV---REWLKPSAGDFVLW-EMNEKIILFGTTMMFASLFPLAPLLALIIGFV 677

  Fly   986 EIRLDAYKMVTQARRPLAERVEDIGAWYGILRIITYTAVVSNAFVIAYTSDFIPRMVYKFVYSET 1050
            ::|:||::::...|:|:......||.|..||..:.|.||.:|||::|:||.|....:....|
 Worm   678 DMRIDAHRLIWFNRKPIPIITNGIGIWLPILTFLQYCAVFTNAFIVAFTSGFCSTFLADGAY--- 739

  Fly  1051 HTLAGYIEHSLSIFNTSDYKEEWGASVSEKDPDTCQYRGYRNGPKDYEPYGLSPHYWHVFAARLA 1115
                                              |..:.                       ||.
 Worm   740 ----------------------------------CTVQN-----------------------RLI 747

  Fly  1116 FVVVFEHVVFVITGIMQFIIPDVPSEVKTQMQREQLLAKEAKYQHGIKRAQGDSQDIMSLFRDTS 1180
            .|:||:::||.:..::..:||.:|:.:|..:::::.:.     .|.:::.            |..
 Worm   748 IVIVFQNLVFGLKYLLSSVIPSIPASIKLALRKKRYVV-----AHIVEKG------------DVP 795

  Fly  1181 NRASIAGSTVTTRGSW 1196
            :|..|...|...:.:|
 Worm   796 HRTRIKKRTRIAKLAW 811

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6938	NP_001261733.1	Anoct_dimer	340..573	CDD:465044	65/271 (24%)
		Anoctamin	576..1149	CDD:461349	164/602 (27%)
anoh-1	NP_001255190.1	Anoct_dimer	36..270	CDD:465044	64/269 (24%)
		Anoctamin	273..781	CDD:461349	164/602 (27%)