Protein Alignment CG6938 and ano5

DIOPT Version :10

• Sequence 1: NP_001261733.1
• Gene: CG6938 / 39362
• FlyBaseID: FBgn0036235
• Length: 1245
• Species: Drosophila melanogaster
• Sequence 2: XP_031756250.1
• Gene: ano5 / 100489787
• XenbaseID: XB-GENE-5952827
• Length: 928
• Species: Xenopus tropicalis
• Alignment Length: 977
• Identity: 384/977 - (39%)
• Similarity: 582/977 - (59%)
• Gaps: 92/977 - (9%)

  Fly   257 GSADRVNQS-YEVMESSHSNVLPDQFGYRQLIPTERKASDTA-SSVSGSYYGSRKASKSNSLGGE 319
            ||..|.::: .|:..:...:||           |:.:..|:| ..::||...:...:.|...|..
 Frog     3 GSGQREDETLIEMTVTDDISVL-----------TDFRTPDSAGEDINGSLLDNNSITDSELPGNS 56

  Fly   320 SG-----------DERRVSKQDREGLDPESLMFRDGRRKVDMVLAWEEEDLGVMTEAEAKRRDNR 373
            .|           :.:|:   |:.....:|:.|.||.|::|.||:: .||.|...|.:|:|   |
 Frog    57 EGLSSTESTFLISNHQRI---DKHAQSKDSVFFWDGSRRIDFVLSY-TEDTGKDAEKKAER---R 114

  Fly   374 RSFMENLIKEGLEVELEDKSQSFNEKTFFLKIHLPWRLETRLAEVMNLKLPVKRFITISVKPSWD 438
            |.|..||.|.|||:|.|||.:|.|.||:|:|||.||.:.|..|||:|||:|:|   ...:|.  |
 Frog   115 REFELNLQKSGLELETEDKKESENGKTYFVKIHAPWEVLTTYAEVLNLKMPLK---ADDLKD--D 174

  Fly   439 EENVVLRNMQYWKDVWQRLTKKIQLDQTLLEGETTFKAATANGNPEEQFIVKDRATAFTSAQRSL 503
            .||::           ..:.|..:|.|.::..|..:..|....:.:|.|..::|...||.:.|:.
 Frog   175 SENIL-----------SHVLKLFKLPQEVMYPEPDYFTAPFRKDKQELFRTEEREKFFTPSTRNR 228

  Fly   504 MVMQVLIRTPFDESD---RSGIRRLMNDGTYLGCFPLHEGRYDRPHSSGISLDRRVLYQTWAHPS 565
            :|..:|.|..:.|.:   :.||:||:.:|:||..:|||:.:|.: .:...:.:|..||..||..:
 Frog   229 IVYYILSRCHYGEEEGKKKFGIKRLLTNGSYLDAYPLHDCQYWK-KTDERNCERYTLYTHWAKFT 292

  Fly   566 QWYKKQPLCLVRKYFGDKIALYFCWLGFYTEMLVYPAVVGTLCFIYGLATLESEDNTPSKEICNE 630
            ::||:|||.|:|||:|:||.:||.|||||||||.|.||||..||:||..|:  :|:..|||||:.
 Frog   293 RFYKEQPLDLIRKYYGEKIGIYFAWLGFYTEMLFYAAVVGFFCFLYGWITM--DDSISSKEICDP 355

  Fly   631 YGTGNITLCPLCDKACSYQRLSESCLFSRLTYLFDNPSTVFFAIFMSFWATTFLELWKRKQSVLV 695
            ...|.|.:||||||.|.:.||:.:|..|:.:::|||.:|:||||||..|.|.|||.|||:|:.|.
 Frog   356 NIGGQIIMCPLCDKRCEFWRLNSTCEPSQYSHMFDNVATLFFAIFMGIWVTLFLEFWKRRQARLE 420

  Fly   696 WEWDLHNVDMDEEN-----RPEFETNATTFRMNPVTREKEPYM--STWNRSIRFVITGSAVLFMI 753
            :||||  ||.:||.     |||:|:..|..:.||||:|.|..:  :..|...:......:|||.|
 Frog   421 YEWDL--VDFEEEQQQLQLRPEYESKCTEKKKNPVTQENELVIKQTACNFLAKMFWCWMSVLFWI 483

  Fly   754 SVVLSAVLGTILYRITLVSVIYGGGGFFVKEH-----------AKLFTSVTAALINLVVIMILTR 807
            ::::::::..|:||:.    :|......:..:           .:|.|||||:::|.|.||||..
 Frog   484 ALIIASIIAIIVYRLW----VYAAFASIMDNNLALKPVSNLLTPQLATSVTASVLNFVTIMILNF 544

  Fly   808 IYHRMAIKLTNLENPRTHTEYEDSYTFKIFFFEFMNFYSSLIYIAFFKGRFFDYPGDDQARKSEF 872
            :|.|:||.:|::|.||||.|||:..|.|:|.|:|:|:|||..|:|||||:|..||.|   ....|
 Frog   545 LYERVAIWITDMEIPRTHLEYENRLTMKMFLFQFVNYYSSCFYVAFFKGKFVGYPAD---YSYLF 606

  Fly   873 FRLKNDICDPAGCLSELCIQLAIIMVGKQCWNNFMEYLFPKFWNWWRQRKHKQATKDESHLHMAW 937
            .:.:|:.|||||||.||..||.|:|.|||.|.|..|...|..|||.::||   |.....:|:..|
 Frog   607 GKWRNEECDPAGCLIELTTQLTIVMAGKQIWGNIQEAFVPWTWNWLKRRK---ARNHPQNLYSRW 668

  Fly   938 EQDYHMQDPGRLALFDEYLEMILQYGFVTLFVAAFPLAPLFALLNNVAEIRLDAYKMVTQARRPL 1002
            |.|..:|..|.|.||:|||||::|:||:|||||:||||||.|||||:.|||:|::|:.||.:||:
 Frog   669 EHDGDLQTFGGLGLFNEYLEMVVQFGFITLFVASFPLAPLLALLNNILEIRVDSWKLTTQFKRPV 733

  Fly  1003 AERVEDIGAWYGILRIITYTAVVSNAFVIAYTSDFIPRMVYKFVYS--ETHTLAGYIEHSLSIFN 1065
            |.:...||.|..||..|...:||:|||::|:|||.|||:||.:.||  |...::|||..|||:||
 Frog   734 AAKAHSIGVWQEILNGIAILSVVTNAFIVAFTSDMIPRLVYYYAYSQDEGTPMSGYIGSSLSVFN 798

  Fly  1066 TSDYKEEWGASVSEKDPDTCQYRGYRNGPKDYEPYGLSPHYWHVFAARLAFVVVFEHVVFVITGI 1130
            .||:||:.....::.:..:|:||.||..|...:.|.::..|||:.||::||:::.|||||::...
 Frog   799 VSDFKEQSMPMENDMNVISCRYRDYRYPPGHEKEYQVTMQYWHILAAKMAFIIIMEHVVFLVKFF 863

  Fly  1131 MQFIIPDVPSEVKTQMQREQLLAKEAKYQHGIKRAQGDSQDIMSLFRDTSNRASIAGSTVTTRGS 1195
            :.::|||||||||.:::||:.|.::..:::.:::.:   |.:.:.....||....    :.|:|.
 Frog   864 VAWLIPDVPSEVKARVKREKFLTQKILHEYELEKLK---QKLCNKNEPLSNDKEF----IATKGK 921

  Fly  1196 WA 1197
            .|
 Frog   922 VA 923

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6938	NP_001261733.1	Anoct_dimer	340..573	CDD:465044	83/235 (35%)
		Anoctamin	576..1149	CDD:461349	272/592 (46%)
ano5	XP_031756250.1	Anoct_dimer	85..300	CDD:465044	83/235 (35%)
		Anoctamin	303..882	CDD:461349	272/592 (46%)