Protein Alignment CG6938 and ano10

DIOPT Version :10

• Sequence 1: NP_001261733.1
• Gene: CG6938 / 39362
• FlyBaseID: FBgn0036235
• Length: 1245
• Species: Drosophila melanogaster
• Sequence 2: XP_002937896.1
• Gene: ano10 / 100487513
• XenbaseID: XB-GENE-955754
• Length: 651
• Species: Xenopus tropicalis
• Alignment Length: 899
• Identity: 209/899 - (23%)
• Similarity: 324/899 - (36%)
• Gaps: 336/899 - (37%)

  Fly   323 ERRVSKQDREGLDPESLMFRDGRRKVDMVLAWEEEDLGVMTEAEAKRRDNRRSFMENLIKEGLEV 387
            :|.:||     |||..|.|               :.|.|:..|:..:.:.|    |.|:|
 Frog     2 KRHLSK-----LDPPDLEF---------------QPLVVIELAKDAKEETR----EWLVK----- 37

  Fly   388 ELEDKSQS------------FNEKTFFLKIHLPWRLETRL---AEVMNLKLPVKRFITISVKPSW 437
            ::.||.:.            .|::.:   |::......||   ||.:.:   ||..|..|:||
 Frog    38 KIRDKKKDGGTQLLIKPLVISNDEEY---IYVVGGSTKRLLLGAESVGM---VKECIDGSMKP-- 94

  Fly   438 DEENVVLRNMQYWKDVWQRLTKKIQLDQTLLEGETTFKAATANGNPEEQFIVK---DRATAFTSA 499
                .:..|.:.:|| |..            :||.....|..      |:|:|   |...|
 Frog    95 ----FIYSNRKEYKD-WTE------------DGENFLSMADC------QYIIKYELDNLRA---- 132

  Fly   500 QRSLMVMQVLIRTPFDESD------------RSGIRRLMNDGTYLGCFPLHEGRYDRPHSSGISL 552
                          .||.:            :|..|||...|..:..||||
 Frog   133 --------------QDEKNIPGYPNSKLYPGKSIFRRLKTSGIMIQVFPLH-------------- 169

  Fly   553 DRRVLYQTWAHPSQWYKK-----QPLCLVRKYFGDKIALYFCWLGFYTEMLVYPAVVGTLCFIYG 612
            |:..| :...|  |||.:     ||:..::.||||.:.|||.:|.::|..|:..|::|
 Frog   170 DKEEL-KRLRH--QWYLRIKLAFQPIDQIQHYFGDTLGLYFAFLEYFTMALIPMALIG------- 224

  Fly   613 LATLESEDNTPSKEICNEYGTGNITLCPLCDKACSYQRLSESCLFSRLTYLF----DNPSTVFFA 673
                                                           :.|.|    |....|.||
 Frog   225 -----------------------------------------------IPYYFFDWEDYDKYVIFA 242

  Fly   674 IFMSFWATTFLELWKRKQSVLVWEW-DLHNVDMDEENRPEFETNATTFRMNPVTREKEPYMSTWN 737
            .|...|:|..||:|||..|.:.:.| .|......||.||.|.   ....:||||..|||..|::.
 Frog   243 TFNLVWSTVILEVWKRLSSAMTYRWGSLIMKRKFEEPRPGFH---GVLGINPVTGRKEPIYSSFK 304

  Fly   738 RSIRFVITGSAVLFMISVVLSAVLGTILYRITLVSVIYGGGGFFVKEHAKL---------FTSV- 792
            |.:|        ::::||....|   .||....|.:||     |..||..|         |:::
 Frog   305 RQLR--------IYLVSVPFVCV---CLYLAIYVMMIY-----FDLEHWALAYHQEQQSTFSNLL 353

  Fly   793 --TAALINLVVIMILTRIYHRMAIKLTNLENPRTHTEYEDSYTFKIFFFEFMNFYSSLIYIAFFK 855
              ..::|..|||.||.|||...|..||:.||.|..:.|::....|:..|..:|.::||.||||.
 Frog   354 LYVPSIIYAVVIEILNRIYKIAAEFLTSWENHRLESSYQNHLVLKVLVFNIVNCFASLFYIAFV- 417

  Fly   856 GRFFDYPGDDQARKSEFFRLKNDICDPAGCLSELCIQLAIIMVGKQCWNNFMEYLFPKFWNWWRQ 920
                                   :||    :..|...||.:::..|..|.|:|.|.|    :|.|
 Frog   418 -----------------------MCD----MKLLRQSLATLLITSQILNQFVEALLP----YWLQ 451

  Fly   921 RKHKQATKDE-------------SHLHMAWEQDYHMQDPGRLALFDEYLEMILQYGFVTLFVAAF 972
            ::..:..|.:             ..:|:..:.|.:      |..||:|||:.|.:|:|:||...:
 Frog   452 KRSSRKIKKKVKSLNVDTDYTLLEQIHLEKDMDTY------LGTFDDYLELFLLFGYVSLFSCVY 510

  Fly   973 PLAPLFALLNNVAEIRLDAYKMVTQARRPLAERVEDIGAWYGILRIITYTAVVSNAFVIAYTSDF 1037
            |||.:||:|||:.|:..||.||....:||.::...:||.|......:...|||:|.
 Frog   511 PLAAIFAVLNNLTEMYSDALKMCRVYKRPFSQPSANIGVWMLAFETMGIIAVVTNC--------- 566

  Fly  1038 IPRMVYKFVYSETHTLAGYIEHSLSIFNTSDYKEEWGASVSEKDPDTCQYRGYRNGPKDYEPYGL 1102
                          ||.|......::|..           |::|
 Frog   567 --------------TLLGMSSQVSTLFQD-----------SKRD--------------------- 585

  Fly  1103 SPHYWHVFAARLAFVVVFEHVVFVITGIMQFIIPDVPSEVKTQMQREQLLAKEA 1156
                      .:..|...||.:..:..|:.|:|||.|.:::.::.|.:..:.||
 Frog   586 ----------LILTVAAIEHALLALKFILAFVIPDKPYDIQVKLARLEFESMEA 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6938	NP_001261733.1	Anoct_dimer	340..573	CDD:465044	52/267 (19%)
		Anoctamin	576..1149	CDD:461349	146/602 (24%)
ano10	XP_002937896.1	Anoctamin	195..621	CDD:461349	146/601 (24%)