DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43896 and CG10140

DIOPT Version :9

Sequence 1:	NP_001261732.1	Gene:	CG43896 / 39360	FlyBaseID:	FBgn0264488	Length:	2113	Species:	Drosophila melanogaster
Sequence 2:	NP_648648.2	Gene:	CG10140 / 39511	FlyBaseID:	FBgn0036363	Length:	297	Species:	Drosophila melanogaster

Alignment Length:	310	Identity:	64/310 - (20%)
Similarity:	106/310 - (34%)	Gaps:	54/310 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 PKPLNCSSYYRCTAKNAVRTVTCAPGKEYNPKNGKCTMAGRSLCKLSLLAPLAEATNVCSTEVNG 102
            ||.|:.|.    |..:.:.|.:...|.||....|.                    .::|....:.
  Fly    21 PKDLDVSG----TTDSTLETDSTTSGLEYGLITGN--------------------LSICGNVADN 61

  Fly   103 AYIANSGSCGEFYICDEQIAYPQKCDLGSFFNETLAACIPDANSTCWQNLCINKTNGVFVENEAN 167
            .::...|.|..:|:|....|...:|:....||....:|:...::.|... | ...|......:..
  Fly    62 VFLPFVGDCNRYYLCRSGQAIELQCEWPYEFNANTQSCVHPGDADCLPT-C-EAFNFSTFSYQRT 124

  Fly   168 CGSYYVCSNGEATLQTCPQGSFFNTSVAACTVDQGNSQCWVNYCIGQDDG---SAVADKSNCSLF 229
            |..|.:|..|:..|:.|..|..:|::...|...| |..|..:.|....:.   ..|..|.:|..:
  Fly   125 CTRYVLCYYGKPVLRQCQDGLQYNSATDRCDFPQ-NVDCVESECSIYSNAYHLRYVPSKVSCQKY 188

  Fly   230 YVCSNNTATAQECPEGSYFESNNWGC-VPGTCTTESPCDD---------STTTTTESCAEETTEP 284
            ::|.|.....|.|..|.:|.:....| :|.....:.|..:         |..||...|      |
  Fly   189 FICGNGIPREQTCTAGLHFSTKCDCCDIPSKSDCQIPAVERKVQQLSRLSPVTTVGIC------P 247

  Fly   285 PASCDCGDIKNADFIPDEENCRKYFICIDGVLVAADCGKGNVFNANLSVC 334
            |:        ...|...|.....|:.|:||..:..||..|..::..:..|
  Fly   248 PS--------GVHFYVHESRRDAYYYCVDGHGLVLDCSAGLWYDPTVQEC 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43896	NP_001261732.1	CBM_14	96..147	CDD:279884	10/50 (20%)
		CBM_14	153..206	CDD:279884	13/52 (25%)
		CBM_14	211..257	CDD:279884	11/49 (22%)
		CBM_14	298..343	CDD:279884	10/37 (27%)
		CBM_14	354..395	CDD:279884
		CBM_14	427..468	CDD:279884
		ChtBD2	488..535	CDD:214696
		CBM_14	544..593	CDD:279884
		CBM_14	<1320..1361	CDD:279884
		ChtBD2	1627..1675	CDD:214696
		CBM_14	1684..1733	CDD:279884
		ChtBD2	1752..1797	CDD:214696
		CBM_14	1820..1868	CDD:279884
		CBM_14	1896..1939	CDD:279884
		ChtBD2	2046..2091	CDD:214696
CG10140	NP_648648.2	CBM_14	63..106	CDD:279884	9/42 (21%)
		CBM_14	111..161	CDD:279884	13/51 (25%)
		CBM_14	178..222	CDD:279884	11/43 (26%)
		CBM_14	246..295	CDD:279884	13/58 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444007
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D33909at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950