DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43896 and CG10725

DIOPT Version :9

Sequence 1:	NP_001261732.1	Gene:	CG43896 / 39360	FlyBaseID:	FBgn0264488	Length:	2113	Species:	Drosophila melanogaster
Sequence 2:	NP_648647.1	Gene:	CG10725 / 39510	FlyBaseID:	FBgn0036362	Length:	269	Species:	Drosophila melanogaster

Alignment Length:	269	Identity:	70/269 - (26%)
Similarity:	110/269 - (40%)	Gaps:	26/269 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 LCKLSLLAPLAEAT------NVCSTEVNGAYIANSGSCGEFYICDEQIAYPQKCDLGSFFNETLA 138
            |..|:|:|.|...:      ||||..||..::...|:|.::::|..:||.|::|....:|:....
  Fly     5 LTLLALVALLGSCSAADGDVNVCSNVVNNLFVPQVGNCSKYFLCMNEIAVPRECPTDYYFDARDQ 69

  Fly   139 ACIPDANSTCWQNLCINKTNGVFVENEANCGSYYVCSNGEATLQTCPQGSFFNTSVAACTVDQGN 203
            .|:|.....|..: |.|:....|. .:..|..|.:|.:|...::.|..|..:|.....|...| .
  Fly    70 ECVPLMEVECIGS-CKNRGLSSFC-YDRTCTKYVLCFDGTPVIRQCSDGLQYNALTDRCDYPQ-Y 131

  Fly   204 SQCWVNYCI---GQDDGSAVADKSNCSLFYVCSNNTATAQECPEGSYFESNNWGC-VPG--TCTT 262
            ..|..|.|.   ..||...:..|:.|..:|:|.:.....|.|..|..:..:...| .|.  .||.
  Fly   132 VDCVDNLCSRNNNPDDIVFIPSKARCDKYYICMDGLPQVQNCTSGLQYNPSTQSCDFPSKVNCTV 196

  Fly   263 ESPCDDSTTTTTESCAEETTEPP--ASCDCGDIKNADFIPDEENCRKYFICIDGVLVAADCGKGN 325
            ||        ...:.......||  |..:|.. :.|.||..::....|:.|::|..|..||..|.
  Fly   197 ES--------LQRNILPFARAPPRLADIECPS-EGAHFIAHQKRQDAYYYCLNGRGVTLDCTPGL 252

  Fly   326 VFNANLSVC 334
            ||:|....|
  Fly   253 VFDAKREEC 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43896	NP_001261732.1	CBM_14	96..147	CDD:279884	14/50 (28%)
		CBM_14	153..206	CDD:279884	12/52 (23%)
		CBM_14	211..257	CDD:279884	11/49 (22%)
		CBM_14	298..343	CDD:279884	13/37 (35%)
		CBM_14	354..395	CDD:279884
		CBM_14	427..468	CDD:279884
		ChtBD2	488..535	CDD:214696
		CBM_14	544..593	CDD:279884
		CBM_14	<1320..1361	CDD:279884
		ChtBD2	1627..1675	CDD:214696
		CBM_14	1684..1733	CDD:279884
		ChtBD2	1752..1797	CDD:214696
		CBM_14	1820..1868	CDD:279884
		CBM_14	1896..1939	CDD:279884
		ChtBD2	2046..2091	CDD:214696
CG10725	NP_648647.1	CBM_14	35..73	CDD:279884	9/37 (24%)
		CBM_14	83..134	CDD:279884	12/52 (23%)
		CBM_14	150..192	CDD:279884	9/41 (22%)
		ChtBD2	216..264	CDD:214696	15/47 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444008
Domainoid	1	1.000	52	1.000	Domainoid score	I18611
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D33909at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950