DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43896 and Mur2B

DIOPT Version :9

Sequence 1:	NP_001261732.1	Gene:	CG43896 / 39360	FlyBaseID:	FBgn0264488	Length:	2113	Species:	Drosophila melanogaster
Sequence 2:	NP_001284789.1	Gene:	Mur2B / 31111	FlyBaseID:	FBgn0025390	Length:	1795	Species:	Drosophila melanogaster

Alignment Length:	300	Identity:	76/300 - (25%)
Similarity:	103/300 - (34%)	Gaps:	78/300 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1633 GLSVPDPTDCTRFYLCLQQVPTILQSCSSGSF---FDSNQGYCRPNDGSCQLAICNGLEDGKLVA 1694
            |...|.|.    :......|..:.:|...|.|   ||.|....|...|              :..
  Fly    53 GYQAPPPV----YQPYYDNVFGVFKSYPGGGFPVRFDYNNRCSRNYIG--------------IKP 99

  Fly  1695 HPEDCRSYYSCSSQNGTSLVQCDEGQYFHSLLSICR------VDHGQCRKVSNQDETETAPRLCY 1753
            ||:..:.||.|..       .|       .:.|.||      ...|:|.:...|...:..|..|.
  Fly   100 HPDQQQYYYVCKP-------DC-------VIFSKCRGLESFNASSGRCVQHVPQHRPDHRPPQCQ 150

  Fly  1754 GLHGVKLPHELYCNLYYACVKGLAIP--VECPVQHQFNPVLSICEPESQAVQPCSNGQLDGNVSY 1816
             ..| :.||...|.:||.|.|....|  ..||....|:||...|.|..|    |.:.::..:.||
  Fly   151 -KEG-RFPHPHDCKVYYRCDKNRTQPWLFACPAGTIFSPVERKCLPGDQ----CPSTEISDSGSY 209

  Fly  1817 VYRCGNL------QDGTFLANRTDCTRYFIC----AGG-VATAQRCAAGTFFDSEQLLCLADDGS 1870
            :.:...|      ::||| .:.|||..|:.|    :|. :.|..:|.....||.|:.||.
  Fly   210 IPQNCELKFPECAEEGTF-RSPTDCALYYTCRLQESGTYLQTRFKCPGSNSFDLERKLCR----- 268

  Fly  1871 CPLVESVPDDDDNPNNQHVP--PDPVVCEGKHGYLMPDPA 1908
             |..| |...|..|....||  |.|        |..|.||
  Fly   269 -PRSE-VDCFDFVPGPVQVPYAPQP--------YYPPYPA 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43896	NP_001261732.1	CBM_14	96..147	CDD:279884
		CBM_14	153..206	CDD:279884
		CBM_14	211..257	CDD:279884
		CBM_14	298..343	CDD:279884
		CBM_14	354..395	CDD:279884
		CBM_14	427..468	CDD:279884
		ChtBD2	488..535	CDD:214696
		CBM_14	544..593	CDD:279884
		CBM_14	<1320..1361	CDD:279884
		ChtBD2	1627..1675	CDD:214696	11/44 (25%)
		CBM_14	1684..1733	CDD:279884	9/54 (17%)
		ChtBD2	1752..1797	CDD:214696	16/46 (35%)
		CBM_14	1820..1868	CDD:279884	17/58 (29%)
		CBM_14	1896..1939	CDD:279884	3/12 (25%)
		ChtBD2	2046..2091	CDD:214696
Mur2B	NP_001284789.1	ChtBD2	88..136	CDD:214696	13/75 (17%)
		CBM_14	150..197	CDD:279884	16/48 (33%)
		CBM_14	221..275	CDD:279884	19/61 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010