Protein Alignment hsc70 and Hsc70-4

DIOPT Version :9

• Sequence 1: NP_956908.1
• Gene: hsc70 / 393586
• ZFINID: ZDB-GENE-040426-1221
• Length: 647
• Species: Danio rerio
• Sequence 2: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Alignment Length: 652
• Identity: 546/652 - (83%)
• Similarity: 595/652 - (91%)
• Gaps: 6/652 - (0%)

Zfish     1 MSKGPAVGIDLGTTYSCVGIFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPSN 65
            |||.|||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||:.
  Fly     1 MSKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQ 65

Zfish    66 TVFDAKRLIGRRFDDPVVQSDMKHWPFKVISDGSKPKMEVEYKGEIKTFFPEEVSSMVLTKMKEI 130
            |:|||||||||:|||..||||||||||:|:|...|||:||.||.|.|||||||:||||||||||.
  Fly    66 TIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKET 130

Zfish   131 SEAYLGKTVSNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGGERNV 195
            :||||||||:||||||||||||||||||||||||||||||||||||||||||||||||..|||||
  Fly   131 AEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNV 195

Zfish   196 LIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKFKKDITGNKRAV 260
            |||||||||||||||:|:|||||||||||||||||||||||:|.||:.|||||.|||:|.||||:
  Fly   196 LIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRAL 260

Zfish   261 RRLRTACERAKRTLSSSTQASIEIDSLYEGADFYTSITRARFEELNADLFRGTLEPVEKALRDAK 325
            |||||||||||||||||||||||||||:||.||||||||||||||||||||.|::||||||||||
  Fly   261 RRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAK 325

Zfish   326 MDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILTGDTSENVQD 390
            :||:.|||||||||||||||:|:||||.|||::||||||||||||||||||||||.||.|:.|||
  Fly   326 LDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQD 390

Zfish   391 LLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNI 455
            ||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||:
  Fly   391 LLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNL 455

Zfish   456 LGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQ 520
            ||||||:||||||||||||||||||||||||||:|:::||.|||||||||||||||||||||||.
  Fly   456 LGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVN 520

Zfish   521 EADQYRAEDEVQREKVTAKNTLESLAFNMKSTVEDDKLQDKISPEDKKTITDKCNEVISWLDKNQ 585
            ||::||.|||.|:|.:.|||.|||..||||:|:::|.|:.|||..|:.||.|||||.|.|||.||
  Fly   521 EAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQ 585

Zfish   586 TAEKDEYEHQQKELEKVCNPIITKLYQGAGGMPGGMPGGMPGGYPGGQGSGSS-----SGPTIEE 645
            .|:|:||||:|||||.||||||||||||||..||||||| |||.||..|:..:     :||||||
  Fly   586 LADKEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGG-PGGMPGAAGAAGAAGAGGAGPTIEE 649

Zfish   646 VD 647
            ||
  Fly   650 VD 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hsc70	NP_956908.1	PTZ00009	1..612	CDD:240227	520/610 (85%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	329/374 (88%)
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	520/610 (85%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	329/374 (88%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	1033	1.000	Domainoid score	I26
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1097	1.000	Inparanoid score	I231
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	1	1.000	-	-		mtm6456
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X148
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.780