DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slc25a1a and sea

DIOPT Version :9

Sequence 1:	NP_956901.1	Gene:	slc25a1a / 393579	ZFINID:	ZDB-GENE-040426-1172	Length:	359	Species:	Danio rerio
Sequence 2:	NP_001027175.1	Gene:	sea / 3772221	FlyBaseID:	FBgn0037912	Length:	317	Species:	Drosophila melanogaster

Alignment Length:	296	Identity:	191/296 - (64%)
Similarity:	226/296 - (76%)	Gaps:	3/296 - (1%)

- Green bases have known domain annotations that are detailed below.

Zfish    61 AAAAIGGRKITHPWKAIFAGGIAGGIEICITFPTEYVKTQLQLDERANPPRYRGIGDCVKLTVQY 125
            ||||..|:.   ..|.|.||||.||||||||:|||||||||||||:....:|.||.||||.||..
  Fly    24 AAAADSGQV---GLKGIVAGGITGGIEICITYPTEYVKTQLQLDEKGAAKKYNGIFDCVKKTVGE 85

Zfish   126 HGLRGLYRGLSSLLYGSIPKSAVRFGTFEVLSNPMRDATGRLDNKASLLCGLGAGIAEAVLVVCP 190
            .|..|||||||.|:||||||||.|||.||.|.:...|:.|:|.|...||||||||:.||::.|.|
  Fly    86 RGFLGLYRGLSVLVYGSIPKSAARFGAFEFLKSNAVDSRGQLSNSGKLLCGLGAGVCEAIVAVTP 150

Zfish   191 METVKVKFIHDQCSLRPRYRGFFHGVREIIRDQGVRGTYQGLTATLLKQGSNQAIRFYVMNLLRN 255
            |||:|||||:||.|..|::|||.|||.:||:.:|:.|.|:|||.|:|||||||||||:|:..|::
  Fly   151 METIKVKFINDQRSGNPKFRGFAHGVGQIIKSEGISGIYKGLTPTILKQGSNQAIRFFVLESLKD 215

Zfish   256 WYKGDDPARDMHPLVTAMFGATAGAASVFGNTPLDVVKTRMQGLEAHRYKSTMDCAFQILKNEGP 320
            .|||||..:.:..||..:|||.||||||||||||||||||||||||.:||:|..||.:|||||||
  Fly   216 LYKGDDHTKPVPKLVVGVFGAIAGAASVFGNTPLDVVKTRMQGLEASKYKNTAHCAVEILKNEGP 280

Zfish   321 LAFYKGTVPRLGRVCLDVAIVFVLYEEVVKLLNNVW 356
            .|||||||||||||||||||.|::|:..:.|.|.||
  Fly   281 AAFYKGTVPRLGRVCLDVAITFMIYDSFMDLFNKVW 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slc25a1a	NP_956901.1	Solcar 1. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00282	71..159		59/87 (68%)
		Mito_carr	72..156	CDD:365909	58/83 (70%)
		Solcar 2. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00282	170..256		52/85 (61%)
		Mito_carr	171..259	CDD:365909	53/87 (61%)
		Mito_carr	266..354	CDD:365909	63/87 (72%)
		Solcar 3. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00282	266..351		62/84 (74%)
sea	NP_001027175.1	PTZ00168	34..302	CDD:185494	180/267 (67%)
		Mito_carr	34..117	CDD:278578	58/82 (71%)
		Mito_carr	125..220	CDD:278578	57/94 (61%)
		Mito_carr	235..314	CDD:278578	60/78 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	135	1.000	Domainoid score	I4920
eggNOG	1	0.900	-	-		E1_KOG0756
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4362
Inparanoid	1	1.050	401	1.000	Inparanoid score	I1885
OMA	1	1.010	-	-		QHG58666
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002928
OrthoInspector	1	1.000	-	-		otm25840
orthoMCL	1	0.900	-	-		OOG6_104005
Panther	1	1.100	-	-	O	PTHR45788
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3276
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.830