DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7248 and Muc68E

DIOPT Version :9

Sequence 1:	NP_648530.1	Gene:	CG7248 / 39356	FlyBaseID:	FBgn0036229	Length:	796	Species:	Drosophila melanogaster
Sequence 2:	NP_996064.1	Gene:	Muc68E / 2768990	FlyBaseID:	FBgn0053265	Length:	1799	Species:	Drosophila melanogaster

Alignment Length:	724	Identity:	167/724 - (23%)
Similarity:	248/724 - (34%)	Gaps:	204/724 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 YCPDGKLFNSPLQICDTPGAVDCEPLPYPTPSPTESP------------PENPCLGTRNNTLLPS 143
            |.|:|    |..:..||..|:|         :.||.|            ||......::.|..|.
  Fly  1212 YDPEG----STTREDDTTVAID---------TTTEKPEDDTTVEDSTPIPEESTTVAQDTTNDPE 1263

  Fly   144 AENCNEFYLCVNDQSKVYRCPGEMLFNPDLNICDDKDNVWCYGDRTTPDP-------------LD 195
            .....|....|...:...:...:........|.::...|   ...||.||             :|
  Fly  1264 GSTTREDDTTVAIDTTTEKPEDDTTVEDSTPIPEESTTV---AQDTTNDPEGSTTREDDTTVAID 1325

  Fly   196 TTTPAEESFTKCEDQEKGTFFPDPENCQQYYYCWGNKSYTILPCPVDNWFNPISGNCGPDIAPDA 260
            |||...|..|..||..     |.||           :|.||..   :..::|.......|....|
  Fly  1326 TTTEKPEDDTTVEDST-----PIPE-----------ESTTIAQ---ETTYDPEGSTTREDDTTVA 1371

  Fly   261 CRETT--PTSTPTIDTSS-----STTVAPTSTEDSVGNPCADQELGASFPIKSDCQSYLLCLNNG 318
            ...||  |....|::.|:     |||||..:|.|..|:...:::...:.
  Fly  1372 IETTTEKPEDDTTVEDSTPIPEESTTVAQDTTNDPEGSTTREEDTTVAI---------------- 1420

  Fly   319 ESTTAKCPSNAWFDPKTGDCGP------------NVSPTACLESFETTTTAV--TTQAPKDPCAD 369
            |:||.| |.:   |....|..|            ...|.......:.||.|:  ||:.|:|   |
  Fly  1421 ETTTEK-PED---DTTVEDSTPIPEETTTVGQETTYDPEGSTTREDDTTVAIETTTEKPED---D 1478

  Fly   370 QELGTSYPLVTNCQQYILCMGNGESTVANCIYNSWFDPQTGNCGPDVSPTACKESGVTTASP--T 432
            ..:..|.|:...           .:|||.   .:.:||: |:...|.:..|.:   .||..|  .
  Fly  1479 TTVEDSTPIPEE-----------TTTVAQ---ETTYDPE-GSTTRDDTTVAIE---TTTEKPEDD 1525

  Fly   433 TTSQATSPLTTPSPTW---STLPTANTEETTTNPP---DIVGICSGESDGYYATYPEVCNK---- 487
            ||::.::|:...|.|.   :|...::|..||||.|   ..:| .|..|.|..:|..:|...
  Fly  1526 TTAEGSTPIPDTSTTVNQDTTTDESSTVVTTTNIPKESTTLG-DSTLSPGENSTAGQVSTSTTLV 1589

  Fly   488 YILCASPVPIAFYCPESLFFNEALQRCVEWESSDCSNGETTTSSPGFTTPSPDTQICSNSTGLN- 551
            |...:||:|             :..|....|.|..|:.||||||    .|.     .|.|||..
  Fly  1590 YDTTSSPIP-------------SSSRSTTLEPSSSSSPETTTSS----LPP-----LSCSTGYQY 1632

  Fly   552 LPYQENCQWYIYCTDENSYMMGICGSEEYFDPWTGKCGFGVSPEACREIQTTSPTVTDSTEGPTT 616
            ||:..||..||:|::.:..:|. |.:..|:|.....|                       .|.:.
  Fly  1633 LPHPTNCHKYIHCSNGHELIME-CPANLYWDYHKFVC-----------------------SGDSG 1673

  Fly   617 VITPSTPGSEPDPCDGAPEGKLVPYPDDCSKFIQCIQPDPIVYDCREGQEFSAALER-CMAPWFA 680
            |....|..|.|:.....|....:.:|.||:.::||..              ..|||| |..|.:.
  Fly  1674 VCYNDTENSNPEEKVCGPGVDFLAHPTDCTMYLQCSN--------------GVALERKCPDPLYW 1724

  Fly   681 NCSIPATTIPPVTIPTTTTTTEKPSPNGICADKAEGSLVPYPGNCSKYIACEDPIPVGYACPEGE 745
            |..|.:     ........|..:.|.:..||  |..:...:..:||||:.|.....|..:|..|.
  Fly  1725 NPEIKS-----CDWSNKYCTNLRASQSISCA--AGMNFNVFQSDCSKYVKCFGLRGVVMSCNSGL 1782

  Fly   746 EFNPIILTC 754
            .:||:...|
  Fly  1783 YWNPVSQVC 1791

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7248	NP_648530.1	CBM_14	62..113	CDD:279884	7/21 (33%)
		CBM_14	136..182	CDD:279884	5/45 (11%)
		CBM_14	207..261	CDD:279884	10/53 (19%)
		CBM_14	293..347	CDD:279884	9/65 (14%)
		CBM_14	367..421	CDD:279884	10/53 (19%)
		CBM_14	470..522	CDD:279884	12/55 (22%)
		CBM_14	544..597	CDD:279884	16/53 (30%)
		CBM_14	630..678	CDD:279884	11/48 (23%)
		CBM_14	710..758	CDD:279884	14/45 (31%)
Muc68E	NP_996064.1	ChtBD2	<1761..1791	CDD:214696	10/29 (34%)
		ChtBD2	1626..1668	CDD:214696	14/42 (33%)
		ChtBD2	1688..1734	CDD:214696	14/64 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D33909at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020