DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7248 and si:ch211-286b4.4

DIOPT Version :9

Sequence 1:	NP_648530.1	Gene:	CG7248 / 39356	FlyBaseID:	FBgn0036229	Length:	796	Species:	Drosophila melanogaster
Sequence 2:	XP_021322239.1	Gene:	si:ch211-286b4.4 / 100005359	ZFINID:	ZDB-GENE-131127-605	Length:	2996	Species:	Danio rerio

Alignment Length:	1010	Identity:	212/1010 - (20%)
Similarity:	286/1010 - (28%)	Gaps:	390/1010 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LSIKGPSSVGWNNVNQNVILSFSKRNSHE--------------------CVVSSQQNS------T 60
            :|..||.|.|:......|:   |..|.:|                    |...:..||      :
Zfish   804 VSPTGPCSAGFLCFGGAVL---SSPNDNETGMLCPSGFYCPAGSFAGIPCPKGTFSNSSQLSKIS 865

  Fly    61 YCESLSNGFY-EYP------------YNCS------AYITC-YDS-CADLEYCPDGKLFNSPL-- 102
            .|::.:.||| ..|            |.||      |.::. |.| |....||..|....:|.
Zfish   866 QCQNCTPGFYCSEPGLTAVSGPCLPGYYCSEGSPSAAPVSAVYGSVCPPGHYCVVGSAVPAPCPV 930

  Fly   103 ---------------------QICDTPGAVDCEPLP------------------------YPTPS 122
                                 |..|..|..:|:|.|                        :..|:
Zfish   931 GTRRPDSRGKATDDCMPCPGGQFQDQRGQSECKPCPTGFHCINLTSGSTGVSSPIICPEGFYCPN 995

  Fly   123 PTESPPENPC-LGTRNNTL-LPSAENCNEFYLCVNDQSKVYRCPGEMLFNPDLNICDDKDNVWCY 185
            .|:|....|| .||.:::| |.|||.|   .:|    ...|.|....|.||. ..|  .....|:
Zfish   996 ETQSGNPVPCPKGTYSDSLGLISAEQC---LVC----PMGYFCGSVGLSNPS-GAC--APGFLCF 1050

  Fly   186 GDRTTPDPLDTTTPAEESFTKCEDQEKGTFFPD---------PENCQQYYYC-WGNKSYTILPCP 240
            ...|.|:|.|.:|              |:..|.         ...|.:.||| ||:.|.....||
Zfish  1051 VQATVPNPTDNST--------------GSLCPPGAFCLLGTRAGECSEGYYCDWGSSSPEQSLCP 1101

  Fly   241 VDNWFNPISGNCGPDIAPDACRETTPTSTPTIDTSSSTTVAPTSTEDSVGNPCADQELGASFPIK 305
            . .::.|...|     .|.||  |..|.:..:..|......|.    .:|..|....:....|
Zfish  1102 A-GFYCPAGTN-----KPLAC--TGGTFSSVMGNSHRENCEPC----PLGFYCQGDAVAEPLP-- 1152

  Fly   306 SDCQSYLLC-LNNGESTTAKCPSNAWFDPKTGDCGPNVSPTACLESFETTTTAVTTQAPKDPCAD 369
              |.....| |:..:.|...||... ..|::|    ..|...||                 ||..
Zfish  1153 --CPPGHFCPLSTSQGTQFPCPPGT-MQPQSG----TASVEECL-----------------PCPS 1193

  Fly   370 QELGTSYPL---VTNCQQYILCMGNGEST--VANCIYNSWFDPQTGN--CGP-DVSPTACKESGV 426
            .....|:.|   ...||....|.....|.  ..|.|      ..|||  |.| ...||     |:
Zfish  1194 GMFCASHGLSEPTGRCQDGFHCPSGATSPDGTGNTI------ESTGNNICPPGHYCPT-----GI 1247

  Fly   427 TTASPTTTSQATSPLTTPSPTWSTLPTAN-------------TEETTTNPPDIVGIC-------- 470
                       .|||..|:.|:|:.|..:             .|:|....|....:|
Zfish  1248 -----------GSPLPCPAGTFSSSPGLSGPEQCQPCPPGYFCEQTAMVHPSQAALCDAGYVCIN 1301

  Fly   471 -----------------SGES------------DGYYATYPE-----VCNKYILC-------ASP 494
                             ||.|            .|.|::.|.     :|....:|       .||
Zfish  1302 GSRSARPVDGLQGYICPSGHSCPIGAPLEVPCEPGTYSSVPGAARCLLCPAGTMCPSPGTLEPSP 1366

  Fly   495 VPIAFYCPESLFFNEALQRCVEWESSDCSNGE----TTTSSPGFTTPSPDTQICSNSTGLNLPYQ 555
            .|:..:||....           |:..|..|.    |...|.....|.|....|| |.|.:.| |
Zfish  1367 CPMGHFCPVGTA-----------EAVPCPVGTLGQGTRAQSEAACVPCPTGLYCS-SAGTSQP-Q 1418

  Fly   556 ENCQWYIYC---------TDENSYMM-GICGSEEYFDP----------------WTGKCGFGVSP 594
            ..||...:|         .:...|:. |.| .:.:|.|                .||    |.|.
Zfish  1419 GQCQQGYFCQGGSPNPAPLNTTGYLRNGPC-PQGHFCPSGTLMPLPCPAGSIRNLTG----GYSL 1478

  Fly   595 EACREIQTTSPTVTDSTEGPT-------------------TVITPS---TPGSEP--DPCDGAPE 635
            |:|..........::..:.||                   ..:.|.   .|...|  .||   |.
Zfish  1479 ESCLPCPAGHYCASEGLDAPTGPCAAGFYCPVDFSSTTAHAFLCPKGHFCPLGSPLALPC---PT 1540

  Fly   636 GKLVPYP--DDCSKFIQCIQPDPIVYDCREGQEFSAALERCMAPWFANCSIPATTIPPVTIPTTT 698
            |:..|.|  |:|             ..||.|.....|:.....|...:...||.|:.|...|..|
Zfish  1541 GQYQPNPGSDNC-------------IPCRPGFYCEEAIIGDPRPCPPHSYCPAATMVPQPCPNGT 1592

  Fly   699 TTTEK-----------PSPN----------GICAD-----------KAEGSLVPYPGNCSKYIAC 731
            .|..:           |.|:          |:||.           ..:.|.:.....|.....|
Zfish  1593 YTPSEVGGLQEERECLPCPSGKFCKAGQVKGLCAAGFLCISGSSDFTPQSSFLINRDQCEWGAQC 1657

  Fly   732 EDPIPVGYACPEGEEFNPIILTCTDPHLAGCNPSA 766
            ..|.|.||.||||.| .|  |:|....|.. ||.|
Zfish  1658 AGPCPAGYYCPEGTE-EP--LSCPSNTLRE-NPGA 1688

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7248	NP_648530.1	CBM_14	62..113	CDD:279884	19/94 (20%)
		CBM_14	136..182	CDD:279884	13/46 (28%)
		CBM_14	207..261	CDD:279884	14/63 (22%)
		CBM_14	293..347	CDD:279884	11/54 (20%)
		CBM_14	367..421	CDD:279884	16/61 (26%)
		CBM_14	470..522	CDD:279884	15/100 (15%)
		CBM_14	544..597	CDD:279884	19/78 (24%)
		CBM_14	630..678	CDD:279884	11/49 (22%)
		CBM_14	710..758	CDD:279884	17/58 (29%)
si:ch211-286b4.4	XP_021322239.1	Ephrin_rec_like	<945..983	CDD:311571	6/37 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D487374at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010