DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17826 and CG17147

DIOPT Version :9

Sequence 1:	NP_648528.1	Gene:	CG17826 / 39354	FlyBaseID:	FBgn0036227	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_001262099.1	Gene:	CG17147 / 40216	FlyBaseID:	FBgn0260393	Length:	337	Species:	Drosophila melanogaster

Alignment Length:	408	Identity:	99/408 - (24%)
Similarity:	144/408 - (35%)	Gaps:	127/408 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 VSKSCASGSYWNSELNICVVDDGQCRPPTCVDGEITPNPDDCAGYLECVDGIIVILTCPDGDYFN 117
            |:.|.:.|.|  .||         ||  ...:|.....|..|..|::|.||...:||||....||
  Fly    19 VALSASVGEY--EEL---------CR--LFKNGTKVRKPGTCDQYIQCYDGNGTVLTCPSNQSFN 70

  Fly   118 STLNRCVEDTCGVCN---GNGTTCTDGELKVDPTNCAGYLACSNGNWVSKQCADGAYFNAILETC 179
            .:...|| ||....|   ||.....|||...|||.|..|..|.||..::..|..|.:|:...::|
  Fly    71 PSKGSCV-DTLANSNKYCGNRCEGLDGEWVADPTECHKYFYCMNGVPLAGMCPVGQHFDERSQSC 134

  Fly   180 VQDDEGICV-----------NCKEGSTKPLADCTMYEIC-SGGKYVTKSCDSGYYWNSQSEVCDV 232
            :...:.:||           |.|..:.|   ||..|..| ..|.:.:|||.   ..:.:.|..||
  Fly   135 LYGVDSMCVDVNNICELVAENTKFRNEK---DCAYYYECDKTGNHASKSCT---VTSKKREYFDV 193

  Fly   233 DNGQC-NGNGTTCTDGE------------LKVDPTNCAGYLACS--------NGNWVSKQCADGA 276
            ::|.| ..|...||...            .|.|...|.||..|.        :..|.  ||.:|.
  Fly   194 ESGNCVEANKVECTAHSKENVCTSSTTMTFKSDQATCRGYFVCKALYPVADLDPLWT--QCPEGY 256

  Fly   277 YFNVTLETCVQDDEGICVNCKEGSTKPLADCTMYEICSGGKYVTKSCDSGYYWNSQSEVCDVDNG 341
            :|:        :|..:|.                                   |..:.||  .:.
  Fly   257 FFD--------EDRQLCA-----------------------------------NPTTVVC--THN 276

  Fly   342 QCNGNGTTCTDGELKVDPTNCAGYLACSNGNWVSKQ-CADGAYFNATLETCVQDDEGICVNCKEG 405
            :|:|.||.....    ...||..|:.|.:...|::: |....:|:.|:|.|
  Fly   277 RCDGRGTMLVTS----SSNNCHNYIRCVDNKEVTEETCHWDHFFDETVEAC-------------- 323

  Fly   406 STKPLADCTMYEICSGGK 423
            |:|     .:|:.|..|:
  Fly   324 SSK-----IIYDKCCDGR 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17826	NP_648528.1	CBM_14	36..74	CDD:279884	6/20 (30%)
		ChtBD2	<89..124	CDD:214696	12/34 (35%)
		CBM_14	145..184	CDD:279884	12/38 (32%)
		CBM_14	251..290	CDD:279884	10/46 (22%)
		CBM_14	357..396	CDD:279884	10/39 (26%)
		CBM_14	463..502	CDD:279884
		CBM_14	563..610	CDD:279884
		CBM_14	621..670	CDD:279884
		CBM_14	697..749	CDD:279884
CG17147	NP_001262099.1	ChtBD2	<44..77	CDD:214696	12/32 (38%)
		ChtBD2	89..136	CDD:214696	16/46 (35%)
		CBM_14	278..332	CDD:279884	17/76 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444021
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D487374at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950