DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17826 and cpg-2

DIOPT Version :9

Sequence 1:	NP_648528.1	Gene:	CG17826 / 39354	FlyBaseID:	FBgn0036227	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_498551.3	Gene:	cpg-2 / 175991	WormBaseID:	WBGene00015102	Length:	524	Species:	Caenorhabditis elegans

Alignment Length:	617	Identity:	131/617 - (21%)
Similarity:	196/617 - (31%)	Gaps:	228/617 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 VQDDEGICVNCKEGSTKPLADC-TMYEICSGGKYVTKSCDSGYYWNSQSEVCD------------ 231
            :||    |.|..:| ...|.:| ..:..||||......|.:...:|....:||
Worm    21 LQD----CTNALDG-LYALGECEPQFLTCSGGIARIMDCPADLIYNEPLLICDWRHNVIGCEGSG 80

  Fly   232 VDNGQCNGNGTTCTDGELKVDPTNCAGYLACSNGNWVSKQCADGAYFNVTLETCVQDDEGICVNC 296
            ..:|:.:|.|:..:.||...:.:..|........:......|.|.......||.    |.:|.|.
Worm    81 ESSGETSGEGSGESSGEASGEGSGEASGEGSGEASGEGSGEASGEGSGSGEETV----ENVCENL 141

  Fly   297 KEGSTKPLADCTMYEICSGGKYVTKSCDSGYYWNSQSEVCDVDNGQCNGNGTTCTDGELKVDPTN 361
            ::|:           ..|||      |.:.|::                    ||        ||
Worm   142 EDGA-----------YSSGG------CTTYYFF--------------------CT--------TN 161

  Fly   362 CAGYLACSNGNWVSKQCADGAYFNATLETCVQDDEGICVNCKEGSTKPLADCTMYEICSGGKYVT 426
            .|.:|:|..          ..:::|..:.|:.  :.:...|||       |.|:    :.|...|
Worm   162 TARFLSCPT----------PLFYDADSQKCIW--KSLVEECKE-------DLTI----TDGSGET 203

  Fly   427 KSCDSGYYWNSQSEVCDVDNGQCN------GNGTTCTDGELKVDPTNCAGYLACSNGNWVSKQCA 485
            ....||   .:..|.....:|:.:      |:|....:|..:::|| |.|.             |
Worm   204 SGEGSG---EASGEASGEGSGEASGESSGQGSGEASGEGSGELEPT-CEGK-------------A 251

  Fly   486 DGAYFNATLETCVQDDEGICVNCKEGSTKPLADCTMYEICSGGKYVTKSCDSGYYWNSQSEVCD- 549
            ||.:.|           |:|             .|.:..||||......|.:...:|....|||
Worm   252 DGIHPN-----------GVC-------------STNFLTCSGGIARIMDCPASLVFNPTILVCDW 292

  Fly   550 -VDNGQCNGNGT---TCTENEVKVNPADCAGYLQCINGVFVARKCSATQFFNTTLKECEVDTENV 610
             .|..:|.|..|   ||.|                 :|.|...:||
Worm   293 PRDVAECAGLPTPQPTCEE-----------------DGYFSFGQCS------------------- 321

  Fly   611 CIPKTCDPDCCDVPNNSIWPVEKNCSAFYQCVNGNKYEQRCSNNLQYNSIIEQCDYPENV----- 670
                                     |:|..|.||......|...|:::....:|||..||
Worm   322 -------------------------SSFTACTNGRAIVMFCPAGLKFSESTVRCDYESNVSECQE 361

  Fly   671 ------------QCDDGSAPPSGPIAGPS---GTYCESHGRCVGQRDGTMFADASGDCSSNYVVC 720
                        |..:||...||..:|.|   |:..|...:|||..:|   ..|.| ||...:.|
Worm   362 TSGEESGEASGEQSGEGSGEASGEASGESSGEGSGVEEQNQCVGLDNG---LHAIG-CSPRVLSC 422

  Fly   721 QCECEVNFTCSSGLLFNLQVKSCDWPD-NVKC 751
            |......|.|.|.|:||.|...||:|. ::||
Worm   423 QNGHVDIFECPSSLVFNDQSLICDYPQTSLKC 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17826	NP_648528.1	CBM_14	36..74	CDD:279884
		ChtBD2	<89..124	CDD:214696
		CBM_14	145..184	CDD:279884	2/3 (67%)
		CBM_14	251..290	CDD:279884	5/38 (13%)
		CBM_14	357..396	CDD:279884	7/38 (18%)
		CBM_14	463..502	CDD:279884	8/38 (21%)
		CBM_14	563..610	CDD:279884	5/46 (11%)
		CBM_14	621..670	CDD:279884	10/48 (21%)
		CBM_14	697..749	CDD:279884	20/52 (38%)
cpg-2	NP_498551.3	CBM_14	24..76	CDD:279884	13/52 (25%)
		CBM_14	138..190	CDD:279884	17/108 (16%)
		ChtBD2	245..293	CDD:214696	20/85 (24%)
		CBM_14	311..359	CDD:279884	17/108 (16%)
		CBM_14	403..454	CDD:279884	20/54 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I3601
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D487374at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.070