DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17826 and R02F2.4

DIOPT Version :9

Sequence 1:	NP_648528.1	Gene:	CG17826 / 39354	FlyBaseID:	FBgn0036227	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_498171.1	Gene:	R02F2.4 / 175755	WormBaseID:	WBGene00019833	Length:	431	Species:	Caenorhabditis elegans

Alignment Length:	492	Identity:	99/492 - (20%)
Similarity:	172/492 - (34%)	Gaps:	153/492 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 GQCRPPTCVDGEITPNPDDCAGYLECVDGIIVILTCPDGDYFNSTLNRCVED------TCG---- 129
            |.|.|                .:|.||.|....:.||:...::..|..|  |      .||
Worm    36 GACEP----------------RFLACVSGEARYMDCPEDLVYHKNLEFC--DWRHNVFECGEEGE 82

  Fly   130 --VCNGNGTTCTDGELKVDPTNCAGYLACSNGNWVSKQCADGAYFNAILETCVQDDEGICVNCKE 192
              ..:|:|:..:.|:.::...:.:|.   |:|:.:.                    |.:|.:.|:
Worm    83 ENEFSGDGSGESSGDEEITFGDSSGE---SSGDELL--------------------ENVCESLKD 124

  Fly   193 GSTKPLADCTMYEICSGGKYVTKSCDSGYYWNSQSEVCD----VDNGQCNG-NGTTC-TDGELKV 251
            |........:.|.||:.|.....||.:...::..::.|.    :|  :|:. :|..| :||  .:
Worm   125 GVYSSGTCSSSYIICNSGSPRFLSCSTPLIYDPTNKKCSWKGMID--ECSQVSGEYCESDG--NI 185

  Fly   252 DPTNCAG-YLACSNGNWVSKQCADGAYFNVTLETCVQDDEGICVNCKEGSTKPLADCTMYEICSG 315
            ..:.|:. :.:||.|....:.|.....||..:.:|  |.....::|.|.|.||
Worm   186 SKSECSNVFFSCSEGIAHRRNCPANLVFNPAISSC--DWPKNVMDCSEKSEKP------------ 236

  Fly   316 GKYVTKSCD--SGYYWNSQSEVCDVDNGQCNGNGTTCTDGELKVDPTNCAGYLACSNGNWVSKQC 378
                 ::|.  .||:          ..|:|:                  :.:.||:||..:...|
Worm   237 -----QNCGEVDGYF----------SFGRCS------------------SSFSACTNGIPIVMFC 268

  Fly   379 ADGAYFNA---------TLETCVQDDEGICVNCKEGSTKPLADCT-----MYEI--------CSG 421
            .||..|:.         .::.|..:..|...|.|  :::.|..||     :|.:        |..
Worm   269 PDGLMFSEKNQMCDYEWNVDECDLESSGFMENYK--ASEALTPCTNMDNGLYALDCTPRVLSCQN 331

  Fly   422 GKYVTKSCDSGYYWNSQSEVCDVDNGQ---CNGNGTTCTDGEL-----KVD----PTNCA-GYLA 473
            |:.....|.....:|..|.:||.....   |..:.....|..:     .:|    .|.|: .|..
Worm   332 GRENIFECPPSLVFNENSLICDYPETSLKCCMEDALLIRDASIGTYDCSIDGLFSSTLCSRNYHK 396

  Fly   474 CSNGNWVSKQCAD-GAYFNATLETCVQDDEGICVNCK 509
            ||||..:..:||| .|.|:|:...||  |..:...|:
Worm   397 CSNGQLIPHECADSNAVFSASAAKCV--DSSLLEQCQ 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17826	NP_648528.1	CBM_14	36..74	CDD:279884
		ChtBD2	<89..124	CDD:214696	7/34 (21%)
		CBM_14	145..184	CDD:279884	3/38 (8%)
		CBM_14	251..290	CDD:279884	9/39 (23%)
		CBM_14	357..396	CDD:279884	9/47 (19%)
		CBM_14	463..502	CDD:279884	16/44 (36%)
		CBM_14	563..610	CDD:279884
		CBM_14	621..670	CDD:279884
		CBM_14	697..749	CDD:279884
R02F2.4	NP_498171.1	CBM_14	25..74	CDD:279884	12/55 (22%)
		ChtBD2	117..165	CDD:214696	10/47 (21%)
		CBM_14	185..229	CDD:279884	9/45 (20%)
		ChtBD2	240..283	CDD:214696	12/70 (17%)
		CBM_14	310..361	CDD:279884	10/50 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I3601
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D487374at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14392
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.070