DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17826 and cpg-1

DIOPT Version :9

Sequence 1:	NP_648528.1	Gene:	CG17826 / 39354	FlyBaseID:	FBgn0036227	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_001021159.1	Gene:	cpg-1 / 175586	WormBaseID:	WBGene00000465	Length:	584	Species:	Caenorhabditis elegans

Alignment Length:	662	Identity:	135/662 - (20%)
Similarity:	197/662 - (29%)	Gaps:	243/662 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 GAYFNAILETCVQDDEG-----------------ICVNC--KEGSTKPLADCT-MYEICSGGKYV 213
            |.|.|..|||...|..|                 |..:|  ||.....:..|: .:..||||...
Worm    23 GMYENLPLETTTLDGSGDGSGADNGFVSGADAVAIDTDCSTKEDGLYAIGGCSPQFLTCSGGISR 87

  Fly   214 TKSCDSGYYWNSQSEVCDVDNG--QCNG--NGTTCTDGELKVDPTNCAGYLACSNGN-------W 267
            ...|.:...::.:...|:....  ||.|  ...|.|......:.|....|.......       .
Worm    88 IMDCPADLIYDPRIVACEYSYNVPQCGGVPQDVTSTQEAYPSEETTVNPYAPVEEATTTPAEDVT 152

  Fly   268 VSKQCADGAYFNVTLETCVQDDEGICVNCKEGSTKPLADCTMYEICSGG---------KYVTKSC 323
            |.::....||..|...:.....|.:.|.. |.:..|.|....|  .:|.         ..|||||
Worm   153 VPEETTTEAYAPVDDYSTTTPAEDVPVPV-ETTASPYAPIVPY--TTGAPAADEPVTRSAVTKSC 214

  Fly   324 ---DSGYYWNSQSEVCDVDNGQCNGNGTTCTDGELKVDPTNCAGYLA----------------CS 369
               ..|:|          ..|:|:.:.|.|::|.|  .|..|...||                |:
Worm   215 VGKADGFY----------SFGECSDHYTACSNGYL--IPMQCPARLAFDEARVICDYVMNVPECT 267

  Fly   370 NGNWVSKQCAD--------------GAYFNATLETCVQDDEGICVNCKEGSTKPLADCTMYEICS 420
            ||:...:..||              |..:..|  |.|.:|    |...:...:|:|
Worm   268 NGSGNDEGSADETTPESSGEMPYSNGYGYEET--TTVAED----VPSTKDYAEPIA--------- 317

  Fly   421 GGKYVTK------------SCDSGYYWNSQSEVCDVDNGQCNGNGTTC--------TDGELKVDP 465
             ..||.:            :...||    :.||.:..........||.        |..|.:| |
Worm   318 -AAYVARYPSEKTTAENVPTTTIGY----EPEVVETTAPYVEETTTTVGYKPEVEETTTEAEV-P 376

  Fly   466 TNCAGY---LACSNGNWVSKQCADGAYFNATLETCVQDDEGICVNCKEGSTK---PLADCTMYE- 523
            |...||   :..:...:| ::....|...:|  |.|.:.|.:     |.:|:   |......||
Worm   377 TTTVGYEPEIVETTAPYV-EETTTAADVPST--TAVYEPEVV-----ETTTEAEVPTTTTVGYEP 433

  Fly   524 --ICSGGKYVTKSCDS--------GYYWNSQSEVCDVDNGQCNGNGTTCTENEVKVNPADCAGYL 578
              :.:...||.::..:        ||    :.||.:           |.||.||   |....||
Worm   434 EVVETTVPYVEETTTAADVPTTTVGY----EPEVEE-----------TTTEAEV---PTTTVGY- 479

  Fly   579 QCINGVFVARKCSATQFFNTTLKECE-VDTENVCIPKTC---------DPDCCDVPNNSIWPVE- 632
                                   |.| |:|....||.|.         .....|||..:: |.|
Worm   480 -----------------------ESEVVETTAADIPTTTIGYAPIVVESTTAADVPTTTV-PAET 520

  Fly   633 --------------KNCSAFYQ-CVNGNKYEQRCSNNLQYNSIIEQCDYPENVQCDDGSAPPSGP 682
                          :.||..|: ||||.:....|.|.|.::        ||..:|
Worm   521 TTEVPACVEGATAIEPCSQHYKNCVNGQEAIFICENGLFFS--------PEQARC---------- 567

  Fly   683 IAGPSGTYCESH 694
              .|:....|.|
Worm   568 --APADQIAECH 577

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17826	NP_648528.1	CBM_14	36..74	CDD:279884
		ChtBD2	<89..124	CDD:214696
		CBM_14	145..184	CDD:279884	7/14 (50%)
		CBM_14	251..290	CDD:279884	6/45 (13%)
		CBM_14	357..396	CDD:279884	13/68 (19%)
		CBM_14	463..502	CDD:279884	10/41 (24%)
		CBM_14	563..610	CDD:279884	11/47 (23%)
		CBM_14	621..670	CDD:279884	17/64 (27%)
		CBM_14	697..749	CDD:279884
cpg-1	NP_001021159.1	CBM_14	61..113	CDD:279884	10/51 (20%)
		CBM_14	214..266	CDD:279884	13/63 (21%)
		CBM_14	<537..576	CDD:279884	14/58 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010