DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7252 and CG31077

DIOPT Version :9

Sequence 1:	NP_648527.1	Gene:	CG7252 / 39353	FlyBaseID:	FBgn0036226	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_733185.2	Gene:	CG31077 / 318583	FlyBaseID:	FBgn0051077	Length:	988	Species:	Drosophila melanogaster

Alignment Length:	559	Identity:	127/559 - (22%)
Similarity:	198/559 - (35%)	Gaps:	148/559 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LQTVVAQ------LTNVCQNQE----DGTRLPLATHCSRFVVCLKGEVSIIGSCPRGLHFNRELR 73
            ||.|.:|      |...|..|.    :|.:.....:|:.::.|:.||. :...||...:::..|.
  Fly   407 LQEVTSQNSCIFDLNGACVGQSTICTEGKKQRDINNCAGYLKCIDGEF-VEEECPESTYYDSNLE 470

  Fly    74 ECDFQWRANC-----LGLSAFAEVDDQCTCDC---------------CA---------EECQDPI 109
            .|.......|     :.:....|.|.:   ||               ||         .||...:
  Fly   471 TCLVDNYGACVTSTSICVEGIVEEDPK---DCAGYNQCVRGKVEPLKCAFGRYFNGTQGECLIDL 532

  Fly   110 DDIDETTTAVTEDCDPD---------------TTTSATEPSDSTEPTDA-------TTDFDDPNN 152
            |::...::.|..|.|.:               |.|..|....|||.::|       :..:.|..:
  Fly   533 DEVCAKSSQVDYDRDLEQFQYSQSTSEYLLEYTNTDTTIADFSTESSNADFNRYTDSNSYTDTES 597

  Fly   153 SSNTTPSSPSVVPSYCKSS----------RTDCVNQKTGT-------YID-----MPGICVRFIQ 195
            ::|..|:|..|.....|::          ..|.::..|||       :|:     .|..|..:|:
  Fly   598 TTNDVPTSTEVSTFDLKTTDLSLQFTTLDGVDNLDINTGTCVYNNTLFIEGIREVNPQDCAGYIE 662

  Fly   196 CNNGCAEEFQCPSGLYFNTAIDDC-----DYWWNVDCTPTADGSTEIEG-PSGTTCSSQGECAGK 254
            |..|.|:|.:|.||.|||....:|     :.....|.|...|..|..|. |:.||  |....|..
  Fly   663 CFGGVAKELKCDSGRYFNETQRNCSVDVDEICLKSDKTIVLDLQTTTESTPNFTT--SVDPFAKC 725

  Fly   255 RDGYMIADP-NSNGFFVC------QCQCPIAMPCSEGLKFNETAQVCDWIKDTKSAIGSSAVQCY 312
            |||.:..|| |..||..|      :..||      .|..:|.|:..|  :.|.::.       |.
  Fly   726 RDGQLRLDPKNCAGFLKCVDGELKEEMCP------SGFFYNSTSSKC--MVDIRAT-------CV 775

  Fly   313 GDLVYNATLDQCDYPENYVPKVECNTTSTVCQNQPEGELFPV-EGKCNMFYKCNFNCAVEQYCPN 376
            .::.|.....:.:.|.|.....:|........|.|.|:.|.| |..|.|        .|.:.|
  Fly   776 TNIKYCIEGVREEDPNNCAGYRQCIRGLVQNLNCPLGQYFNVAERDCLM--------DVHKVC-- 830

  Fly   377 NLVYNPNTEECEYPQDYVCPWEYTPPSGPNAGP--------SGIACESNGRCMGQREGTYLKSTT 433
                 ..|||. |..|.|   ::.....|...|        :|:..:...:|   |||.:.....
  Fly   831 -----ARTEEV-YKSDEV---QHNDTGPPMTKPDESCIRDINGVCVDPLAKC---REGQHKLDPN 883

  Fly   434 NCSNYVVCQCECEVEMECADGLYWDESLQTCNYKNQVTC 472
            ||:.|:.||....:|..|.:|.|:|..::.|....:..|
  Fly   884 NCAGYLKCQNGELIEELCPNGFYYDFLMKICLVDRRGIC 922

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7252	NP_648527.1	CBM_14	30..79	CDD:279884	11/52 (21%)
		CBM_14	175..226	CDD:279884	18/67 (27%)
		CBM_14	251..296	CDD:279884	16/51 (31%)
		CBM_14	343..394	CDD:279884	15/51 (29%)
		CBM_14	420..471	CDD:279884	15/50 (30%)
CG31077	NP_733185.2	CBM_14	43..81	CDD:279884
		ChtBD2	<212..245	CDD:214696
		CBM_14	267..308	CDD:279884
		CBM_14	439..472	CDD:279884	7/33 (21%)
		CBM_14	733..769	CDD:279884	12/43 (28%)
		CBM_14	881..914	CDD:279884	10/32 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45472930
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D29657at33392
OrthoFinder	1	1.000	-	-		FOG0012713
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950